Company lists · Data refreshed September 2026

Top 25 Trial management software companies based in the United States

RevenueBase identified 1,163 trial management software companies headquartered in the United States as of September 2026 and tracks 136,893 professional contacts across them, including 64,709 with verified work emails and 33,997 with mobile numbers. New York is the largest hub.

This list covers trial management software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 6, 2026 86% judged on-target in blind review
1,163Companies
136,893Contacts tracked
64,709Verified emails
33,997Mobile numbers
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The 25 largest trial management software companies based in the United States

Ranked by team size
Top 25 of 1,163 trial management software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 6, 2026. RevenueBase Smart Search rates how each company's information relates to trial management software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceWaltham, MA, United StatesHQ checked Sep 6, 202610001+20,530 contacts →

“The PPD™ clinical research business of Thermo Fisher Scientific, the world leader in serving science, enables customers to accelerate innovation and drug development through…”

Source: company website · checked Sep 6, 2026
2Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 6, 202610001+19,257 contacts →

“Parexel is a leading global clinical research organization (CRO) providing insights-driven Clinical and Consulting solutions to the world’s life sciences industry.”

Source: company website · checked Sep 6, 2026
3Indirect evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 6, 202610001+10,632 contacts →

“Fortrea (Nasdaq: FTRE) is a leading global clinical research organization (CRO) dedicated to providing innovative clinical development solutions to the life sciences industry.”

Source: company website · checked Sep 6, 2026
4Indirect evidenceCincinnati, OH, United StatesHQ checked Sep 6, 20265,001-10,0005,960 contacts →

“Medpace is a scientifically-driven, global, full-service clinical contract research organization (CRO) providing Phase I-IV clinical development services to the biotechnology…”

Source: company website · checked Sep 6, 2026
5Indirect evidencePrinceton, NJ, United StatesHQ checked Sep 6, 202610001+5,220 contacts →

“As the drug development business of Laboratory Corporation of America Holdings (Labcorp) and the world’s most comprehensive drug development #CRO service company, we have helped…”

Source: company website · checked Sep 6, 2026
6Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 6, 202610001+4,708 contacts →

“PRA is now an ICON plc company.”

Source: company website · checked Sep 6, 2026
7Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 6, 20261,001-5,0003,790 contacts →

“Clario, part of Thermo Fisher Scientific, is a leading provider of endpoint data solutions to the life sciences industry.”

Source: company website · checked Sep 6, 2026
8Partial evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 6, 20261,001-5,0003,440 contacts →

“Worldwide Clinical Trials (Worldwide) is a global CRO serving development-driven biopharmaceutical companies, with more than 4,400 professionals operating across more than 70…”

Source: company website · checked Sep 6, 2026
9Partial evidenceNew York, NY, United StatesHQ checked Sep 6, 20261,001-5,0002,704 contacts →

“Medidata is powering smarter treatments and healthier people through digital solutions to support clinical trials.”

Source: company website · checked Sep 6, 2026
10Indirect evidenceMorrisville, NC, United StatesHQ checked Sep 6, 20261,001-5,0002,584 contacts →

“Premier Research International LLC (Premier) is a global leader in clinical research and consulting services with expertise in driving an efficient and effective path to market…”

Source: company website · checked Sep 6, 2026
11Indirect evidenceBlue Bell, PA, United StatesHQ checked Sep 6, 20261,001-5,0002,083 contacts →

“For 25+ years, Signant Health has been pioneering solutions and methodologies that propel clinical research programs toward regulatory success.”

Source: company website · checked Sep 6, 2026
12Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 6, 20261,001-5,0002,079 contacts →

“At ProPharma, we help pharmaceutical, biotechnology, and medical device companies bring life-changing therapies to market.”

Source: company website · checked Sep 6, 2026
13Indirect evidenceBethesda, MD, United StatesHQ checked Sep 6, 20261,001-5,0001,781 contacts →

“Precision for Medicine is an industry-leading global clinical research services organization, purpose-built to improve the clinical research and development process for new…”

Source: company website · checked Sep 6, 2026
14Strong evidenceCambridge, MA, United StatesHQ checked Sep 6, 20261,001-5,0001,580 contacts →

“Cytel is the world’s leading data-science CRO, driving advancements in human health through robust analytics and innovative clinical trial software.”

Source: company website · checked Sep 6, 2026
15Indirect evidencePrinceton, NJ, United StatesHQ checked Sep 6, 20261,001-5,0001,293 contacts →

“ERT, the global clinical endpoint technology leader, and Bioclinica, a technological and scientific leader in medical imaging, is now the combined company of Clario.”

Source: company website · checked Sep 6, 2026
16Partial evidenceConshohocken, PA, United StatesHQ checked Sep 6, 20261,001-5,0001,255 contacts →

“Suvoda is a global clinical trial technology company, now strengthened by our merger with Greenphire.”

Source: company website · checked Sep 6, 2026
17Indirect evidenceCary, NC, United StatesHQ checked Sep 6, 20261,001-5,0001,103 contacts →

“WCG is a true partner to research sponsors, CROs, sites and participants in navigating the clinical research journey.”

Source: company website · checked Sep 6, 2026
18Partial evidenceCovington, KY, United StatesHQ checked Sep 6, 20261,001-5,0001,043 contacts →

“CTI Clinical Trial and Consulting Services is a global, privately held, research service organization, delivering a complete spectrum of clinical trial and consulting services…”

Source: company website · checked Sep 6, 2026
19Partial evidenceGaithersburg, MD, United StatesHQ checked Sep 6, 20261,001-5,000990 contacts →

“Navitas Life Sciences is a global Clinical Research partner with over 35 years of expertise in Clinical, Regulatory, Safety, and Data Management solutions.”

Source: company website · checked Sep 6, 2026
20Indirect evidenceCary, NC, United StatesHQ checked Sep 6, 20261,001-5,000977 contacts →

“Allucent is on a mission to help bring new therapies to light by solving the distinct challenges of small and mid-sized biotech companies.”

Source: company website · checked Sep 6, 2026
21Indirect evidenceDurham, NC, United StatesHQ checked Sep 6, 20261,001-5,000971 contacts →

“Velocity is the world’s leading organization of fully integrated clinical research sites.”

Source: company website · checked Sep 6, 2026
22Partial evidenceRockville, MD, United StatesHQ checked Sep 6, 20261,001-5,000961 contacts →

“Emmes is a Contract Research Organization delivering complex clinical trials through therapeutic expertise, scientific rigor, and technology-enabled execution.”

Source: company website · checked Sep 6, 2026
23Indirect evidenceDeerfield, IL, United StatesHQ checked Sep 6, 2026501-1,000960 contacts →

“Advanced Clinical is a clinical development and strategic resourcing organization committed to providing a better clinical experience across the drug development journey.”

Source: company website · checked Sep 6, 2026
24Indirect evidenceDurham, NC, United StatesHQ checked Sep 6, 20261,001-5,000915 contacts →

“BioAgilytix is a leading global contract research organization focused on supporting pharmaceutical and biotech partners in all phases of drug development.”

Source: company website · checked Sep 6, 2026
25Indirect evidenceCanton, MI, United StatesHQ checked Sep 6, 2026501-1,000876 contacts →

“MMS Holdings (MMS) is an award-winning, data-focused clinical research organization (CRO) that supports the pharmaceutical and biotech industries with a proven, scientific…”

Source: company website · checked Sep 6, 2026

Showing 25 of 1,163 trial management software companies based in the United States

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Trial management software companies based in the United States at a glance

As of Sep 6, 2026
47.3%Verified-email coverage
24.8%Mobile-number coverage
117.7Average contacts per company
11-50Median size (employees)
3.3%Largest-city concentration · New York
Sep 6, 2026Page data refreshed

Companies by employee count

1-10
381
11-50
444
51-200
196
201-500
67
501-1,000
24
1,001-5,000
36
5,001-10,000
3
10001+
10

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among trial management software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “trial management software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names trial management software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among trial management software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 64,709 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 6, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names trial management software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many trial management software companies are there based in the United States?

RevenueBase identified 1,163 trial management software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

PPD, headquartered in Waltham, tops this list with the largest team on record.

Which city has the most trial management software companies?

New York leads with 38 headquartered companies, followed by San Francisco (34) and Boston (30).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 64,709 verified decision-maker contacts tracked across these 1,163 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.