Company lists · Data refreshed September 2026
Top 25 Practice management software systems based in the United States
RevenueBase identified 746 practice management software systems headquartered in the United States as of September 2026 and tracks 48,874 professional contacts across them, including 21,021 with verified work emails. New York is the largest hub.
This list covers practice management software systems headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 21, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest practice management software systems based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 8,486 contacts → | ||||
Partial evidence “athenahealth strives to cure complexity and simplify the practice of healthcare.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 2 | 5,260 contacts → | ||||
Strong evidence “eClinicalWorks is a privately held leader in healthcare IT, providing comprehensive Electronic Health Record (EHR) and Practice Management (PM) solutions used by more than medical…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 3 | 4,149 contacts → | ||||
Indirect evidence “Allscripts is now Veradigm.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 4 | 2,970 contacts → | ||||
Partial evidence “NextGen Healthcare is the technology partner for diverse ambulatory practices with evolving business needs.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 5 | 1,760 contacts → | ||||
Partial evidence “At ModMed, we empower medical practices to grow and scale by delivering better patient experiences with cloud, data and AI technologies.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 6 | 1,729 contacts → | ||||
Indirect evidence “Join CureMD – Innovating Healthcare, Empowering People At CureMD, we are at the forefront of healthcare innovation, driven by a passion for creating a better future.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 7 | 1,676 contacts → | ||||
Indirect evidence “Phreesia was founded in 2005 to help patients take an active role in their care.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 8 | 1,090 contacts → | ||||
Indirect evidence “Weave is the all-in-one experience platform for small- and medium-sized healthcare businesses.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 9 | 968 contacts → | ||||
Indirect evidence “Cognizant (Nasdaq-100: CTSH) is one of the world's leading professional services companies, transforming clients' business, operating and technology models for the digital era.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 10 | 884 contacts → | ||||
Strong evidence “Zotec Partners (Zotec) is the country’s largest, privately held provider of patient engagement, revenue cycle and practice management solutions for healthcare practices and their…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 11 | 700 contacts → | ||||
Indirect evidence “Empowering our clients with cutting edge technology to meet future healthcare needs today.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 12 | 669 contacts → | ||||
Partial evidence “AdvancedMD is how private healthcare practices move care forward.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 13 | 622 contacts → | ||||
Partial evidence “We are Tebra, the complete operating system for modern healthcare.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 14 | 619 contacts → | ||||
Partial evidence “Join over Health and Wellness professionals in growing their private practice with SimplePractice.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 15 | 479 contacts → | ||||
Strong evidence “For 30 years, Surgical Information Systems (SIS) has empowered surgical providers to Operate Smart™ by delivering innovative software and services that drive clinical, financial…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 16 | 477 contacts → | ||||
Indirect evidence “CompuGroup Medical is a leading provider of healthy solutions for healthy patients and healthy providers.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 17 | 462 contacts → | ||||
Partial evidence “PrognoCIS, developed by Bizmatics, is a leading cloud-based EHR and healthcare technology platform that helps medical practices, physician groups, and multi-specialty…” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 18 | 406 contacts → | ||||
Partial evidence “Medico is a 20+ year old healthcare services, technology and management company.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 19 | 357 contacts → | ||||
Indirect evidence “For those looking to do meaningful work that matters, this could be the place for you.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 20 | 354 contacts → | ||||
Indirect evidence “Rectangle Health simplifies patient and payer payments so healthcare organizations can collect more, grow more, and serve more patients.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 21 | 332 contacts → | ||||
Indirect evidence “PerfectServe accelerates speed to care by optimizing provider schedules, streamlining clinical communication, and engaging patients and their families in the care experience.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 22 | 306 contacts → | ||||
Strong evidence “TherapyNotes® is an online practice management system for behavioral health, featuring robust notes, scheduling, and billing features.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 23 | 302 contacts → | ||||
Strong evidence “Dental software designed to help practices integrate calls, texts, emails, patient forms, online scheduling, analytics, reviews, and payments in one place.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 24 | 220 contacts → | ||||
Indirect evidence “How do you keep your optometry and ophthalmology exam lanes moving while managing compliance, costs, cash flow, and staff?” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
| 25 | 216 contacts → | ||||
Partial evidence “NexHealth connects practices, developers, and patients.” Source: RevenueBase Database · checked Sep 21, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: practice management software systems. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names practice management software systems.
- Partial evidence
- Its own public description names part of practice management software systems, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name practice management software systems. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 746 practice management software systems based in the United States
See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 21,021 reachable decision-makers.
Free signup · no credit card
Practice management software systems based in the United States at a glance
As of Sep 21, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 746 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among practice management software systems, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “practice management software systems”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names practice management software systems), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among practice management software systems, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 21,021 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 21, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names practice management software systems, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many practice management software systems are there based in the United States?
RevenueBase identified 746 practice management software systems headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Athenahealth, headquartered in Boston, tops this list with the largest team on record.
Which city has the most practice management software systems?
New York leads with 21 headquartered companies, followed by Houston (18) and Austin (16).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 21,021 verified decision-maker contacts tracked across these 746 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 21, 2026.
Ready to reach these companies? Verified emails and direct dials for all 746 practice management software systems based in the United States. Start with a free account, no credit card.
Download this list →Related lists
Practice management software systems by geography
- Practice management software systems based in Australia
- Practice management software systems based in Brazil
- Practice management software systems based in Canada
- Practice management software systems based in France
- Practice management software systems based in Germany
- Practice management software systems based in India
- Practice management software systems based in the Netherlands
- Practice management software systems based in South Africa
- Practice management software systems based in Switzerland
- Practice management software systems based in the United Kingdom
About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
More company lists
- All company lists
- Lists by location
- Lists A-Z
- New lists
- Practice management software systems based in Australia
- Practice management software systems based in Brazil
- Practice management software systems based in Canada
- Practice management software systems based in France
- Practice management software systems based in Germany
- Practice management software systems based in India