Company lists · Data refreshed September 2026

Top 24 Defi protocol companies based in the United States

RevenueBase identified 73 company matches for defi protocol companies associated with the United States as of September 2026 and tracks 956 professional contacts across them, including 149 with verified work emails. San Francisco is the largest hub.

This list covers company matches for defi protocol companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 19, 2026 How this list was built
73Companies
956Contacts tracked
149Verified emails
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The 24 largest defi protocol companies based in the United States

Ranked by team size
Top 24 of 73 company matches for defi protocol companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 19, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchNew York, NY, United StatesHQ recorded Sep 19, 202651-200228 contacts →

Exact match

“Uniswap Labs builds products that help millions of people access DeFi simply and securely - from the Uniswap Web App and Wallet to crypto infrastructure like the Uniswap Trading…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
2Exact matchHoboken, NJ, United StatesHQ recorded Sep 19, 2026501-1,000125 contacts →

Exact match

“Celsius helps over a million customers worldwide to find the path towards financial independence through a compounding yield service and instant low-cost loans accessible via a…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
3Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-5053 contacts →

Exact match

“At Zerion, we are on a mission to empower more people around the world with efficient, transparent, and censorship-resistant financial services.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
4Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-5043 contacts →

Exact match

“Origin Protocol builds permissionless DeFi products for enhanced yield on ETH and stablecoins.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
5Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-5030 contacts →

Exact match

“Teller is a non-custodial lending book that facilitates DeFi loans on Ethereum and Polygon.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
6Exact matchNew York, NY, United StatesHQ recorded Sep 19, 20261-1027 contacts →

Exact match

“Ellipsis Labs is a venture-backed New York based startup building differentiated products in decentralized finance.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
7Exact matchNew York, NY, United StatesHQ recorded Sep 19, 202611-5022 contacts →

Exact match

“Magna is building a platform to turn DeFi investments into financial primitives.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
8Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-5016 contacts →

Exact match

“AlphaGrowth is a protocol management firm specializing in DeFi Operations, Business Development, and industry leading operational strategy.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
9Exact matchSheridan, WY, United StatesHQ recorded Sep 19, 202611-5016 contacts →

Exact match

“At Liqwid Labs our team of software engineers build Decentralized Finance products on Cardano.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
10Exact matchNew York, NY, United StatesHQ recorded Sep 19, 202611-5014 contacts →

Exact match

“Loopscale is building the next generation of credit markets on efficient, open networks.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
11Exact matchSan Mateo, CA, United StatesHQ recorded Sep 19, 202611-5013 contacts →

Exact match

“Cred is a decentralized global lending platform that facilitates open access to credit anywhere and anytime.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
12Exact matchNashville, TN, United StatesHQ recorded Sep 19, 202611-5010 contacts →

Exact match

“Number Group is a DeFi-focused venture studio with the mission of incubating and building successful Web3 products from concept to market.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
13Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-5010 contacts →

Exact match

“The legacy financial system is slow, inefficient, and constrained by intermediaries.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
14Exact matchChambersburg, United StatesHQ recorded Sep 19, 202611-507 contacts →

Exact match

“HLWGroup is a leading technology company exclusively dedicated to the pioneering fields of cryptocurrency and Decentralized Finance (DeFi).”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
15Exact matchSan Rafael, CA, United StatesHQ recorded Sep 19, 202611-507 contacts →

Exact match

“The Credora Network is powered by a Consensus Ratings Protocol, providing market participants and protocols vital risk information.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
16Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202651-2006 contacts →

Exact match

“TrustToken envisions a world where financial freedom is as accessible as the internet.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
17Exact matchTroy, MI, United StatesHQ recorded Sep 19, 20261-103 contacts →

Exact match

“Axis Technologies Group, Inc.(AXTG) is a holding company that promote decentralized finance business and business focus to make these innovations comes true.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
18Exact matchLos Angeles, CA, United StatesHQ recorded Sep 19, 20261-103 contacts →

Exact match

“Archimedes is an open source lending protocol enabling superior capital efficiency in DeFi through our flagship product: the Archimedes Vault.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
19Exact matchMiami, FL, United StatesHQ recorded Sep 19, 20261-102 contacts →

Exact match

“Savvy DeFi is a decentralized lending protocol that empowers crypto users to unlock their liquidity by giving an advance on future yield immediately, with non-liquidating…”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
20Exact matchMiami, FL, United StatesHQ recorded Sep 19, 202611-502 contacts →

Exact match

“OpulenceX stands as a multifaceted DeFi Protocol, offering an extensive array of cutting-edge products and services that redefine the landscape of decentralized finance.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
21Exact matchMountain View, CA, United StatesHQ recorded Sep 19, 202611-501 contacts →

Exact match

“WeTrust is a platform for decentralized financial apps, powered by blockchain technology.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
22Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-501 contacts →

Exact match

“Our vision is to provide world-class services through decentralized technology with special interest in the financial and video-gaming sectors.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
23Exact matchSan Francisco, CA, United StatesHQ recorded Sep 19, 202611-501 contacts →

Exact match

“Sharky aims to bridge the gap between on chain assets and DeFi protocols, by creating contracts for lenders and borrowers, increasing liquidity in the ecosystem.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase
24Exact matchNew York, NY, United StatesHQ recorded Sep 19, 20261-101 contacts →

Exact match

“DeFi borrowing made easy, for everyone.”

Recorded in the RevenueBase company graph · Sep 19, 2026 · View company records in RevenueBase

Showing 24 of 73 defi protocol companies based in the United States

See the full list, filter by size, metro and specialty, and access 149 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Defi protocol companies based in the United States at a glance

As of Sep 19, 2026
15.6%Verified-email coverage
13.1Average contacts per company
11-50Median size (employees)
28.8%Largest-city concentration · San Francisco
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
29
11-50
39
51-200
4
501-1,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 73 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “defi protocol companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 149 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “defi protocol companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many defi protocol companies are there based in the United States?

RevenueBase identified 73 company matches for defi protocol companies associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Uniswap tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most defi protocol companies?

San Francisco leads with 21 company records, followed by New York (11) and Miami (4).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 149 professional contacts with verified work emails tracked across these 73 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.