Company lists · Data refreshed September 2026

Top 25 Defi protocol companies worldwide

RevenueBase identified 444 defi protocol companies worldwide as of September 2026 and tracks 3,111 professional contacts across them, including 443 with verified work emails. The United States is the largest market and San Francisco the largest hub.

This list covers defi protocol companies worldwide, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026. Country and city lists for defi protocol companies follow the table.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
444Companies
3,111Contacts tracked
443Verified emails
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The 25 largest defi protocol companies worldwide

Ranked by team size
Top 25 of 444 defi protocol companies worldwide, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to defi protocol companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 202651-200228 contacts →

Partial evidence

“Uniswap Labs builds products that help millions of people access DeFi simply and securely - from the Uniswap Web App and Wallet to crypto infrastructure like the Uniswap Trading…”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidenceHoboken, NJ, United StatesHQ checked Sep 19, 2026501-1,000125 contacts →

Indirect evidence

“Celsius helps over a million customers worldwide to find the path towards financial independence through a compounding yield service and instant low-cost loans accessible via a…”

Source: RevenueBase Database · checked Sep 19, 2026
3Partial evidenceBritish Virgin IslandsHQ checked Sep 19, 202651-200102 contacts →

Partial evidence

“Kyber Network makes DeFi easy, fast, and secure.”

Source: RevenueBase Database · checked Sep 19, 2026
4Indirect evidenceUnited StatesHQ checked Sep 19, 202651-20057 contacts →

Indirect evidence

“Building the largest sustainable hub for on-chain finance with core innovative pillars Mantle Network, mETHProtocol, and Ignition FBTC.”

Source: RevenueBase Database · checked Sep 19, 2026
5Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5053 contacts →

Indirect evidence

“At Zerion, we are on a mission to empower more people around the world with efficient, transparent, and censorship-resistant financial services.”

Source: RevenueBase Database · checked Sep 19, 2026
6Strong evidenceZug, SwitzerlandHQ checked Sep 19, 202611-5052 contacts →

Strong evidence

“An ecosystem of decentralized, open-source DeFi protocols that foster on-chain trading and liquidity.”

Source: RevenueBase Database · checked Sep 19, 2026
7Partial evidenceUnited StatesHQ checked Sep 19, 2026n/a47 contacts →

Partial evidence

“UniLend is a Multichain protocol for Lending & Borrowing all ERC20 tokens permissionlessly.”

Source: RevenueBase Database · checked Sep 19, 2026
8Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5043 contacts →

Strong evidence

“Origin Protocol builds permissionless DeFi products for enhanced yield on ETH and stablecoins.”

Source: RevenueBase Database · checked Sep 19, 2026
9Partial evidenceSingaporeHQ checked Sep 19, 202611-5040 contacts →

Partial evidence

“Kima is the fintech fixing DeFi’s interoperability problem.”

Source: RevenueBase Database · checked Sep 19, 2026
10Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5030 contacts →

Partial evidence

“Teller is a non-custodial lending book that facilitates DeFi loans on Ethereum and Polygon.”

Source: RevenueBase Database · checked Sep 19, 2026
11Partial evidenceLondon, United KingdomHQ checked Sep 19, 202611-5029 contacts →

Partial evidence

“Euler Labs is a talented, international, and fully remote team of professionals who believe in DeFi’s promise and egalitarian ethos.”

Source: RevenueBase Database · checked Sep 19, 2026
12Indirect evidenceUnited StatesHQ checked Sep 19, 202651-20028 contacts →

Indirect evidence

“Trade, borrow, and invest on a single decentralized platform, powered by blockchain technology.”

Source: RevenueBase Database · checked Sep 19, 2026
13Partial evidenceDecentralized, United StatesHQ checked Sep 19, 202611-5028 contacts →

Partial evidence

“Balancer’s mission is to accelerate innovation in DeFi by providing access to secure infrastructure for liquidity applications.”

Source: RevenueBase Database · checked Sep 19, 2026
14Indirect evidenceNew York, NY, United StatesHQ checked Sep 19, 20261-1027 contacts →

Indirect evidence

“Ellipsis Labs is a venture-backed New York based startup building differentiated products in decentralized finance.”

Source: RevenueBase Database · checked Sep 19, 2026
15Partial evidenceUnited StatesHQ checked Sep 19, 202611-5027 contacts →

Partial evidence

“Folks Finance is a pioneering DeFi platform that offers cross-chain lending, borrowing, staking and trading.”

Source: RevenueBase Database · checked Sep 19, 2026
16Indirect evidenceUnited StatesHQ checked Sep 19, 202611-5027 contacts →

Indirect evidence

“Institutional-grade investment opportunities for everyone.”

Source: RevenueBase Database · checked Sep 19, 2026
17Strong evidenceLondon, United KingdomHQ checked Sep 19, 202611-5024 contacts →

Strong evidence

“Arkis is a DeFi prime brokerage protocol for institutional borrowers and lenders to interact in a zero-trust environment.”

Source: RevenueBase Database · checked Sep 19, 2026
18Partial evidenceNew York, NY, United StatesHQ checked Sep 19, 202611-5022 contacts →

Partial evidence

“Magna is building a platform to turn DeFi investments into financial primitives.”

Source: RevenueBase Database · checked Sep 19, 2026
19Strong evidenceZug, SwitzerlandHQ checked Sep 19, 202611-5020 contacts →

Strong evidence

“Zap is a cross-chain multifunctional DeFi protocol.”

Source: RevenueBase Database · checked Sep 19, 2026
20Partial evidenceLat Yao, ThailandHQ checked Sep 19, 202611-5019 contacts →

Partial evidence

“ForwardX is a DeFi platform in the cryptocurrency ecosystem.”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidenceUnited StatesHQ checked Sep 19, 202611-5018 contacts →

Partial evidence

“Venus Protocol (“Venus”) is an algorithmic-based money market system designed to bring a complete decentralized finance-based lending and credit system onto Binance Smart Chain.”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceMadrid, SpainHQ checked Sep 19, 202611-5017 contacts →

Partial evidence

“Fintech & DeFi.”

Source: RevenueBase Database · checked Sep 19, 2026
23Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 19, 202611-5016 contacts →

Strong evidence

“AlphaGrowth is a protocol management firm specializing in DeFi Operations, Business Development, and industry leading operational strategy.”

Source: RevenueBase Database · checked Sep 19, 2026
24Indirect evidenceSheridan, WY, United StatesHQ checked Sep 19, 202611-5016 contacts →

Indirect evidence

“At Liqwid Labs our team of software engineers build Decentralized Finance products on Cardano.”

Source: RevenueBase Database · checked Sep 19, 2026
25Indirect evidenceUnited StatesHQ checked Sep 19, 202611-5016 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 444 defi protocol companies worldwide

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Defi protocol companies worldwide at a glance

As of Sep 19, 2026
14.2%Verified-email coverage
7.0Average contacts per company
1-10Median size (employees)
4.7%Largest-city concentration · San Francisco
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
233
11-50
186
51-200
17
201-500
5
501-1,000
1
10001+
1

Email recency is reported on each country list linked below.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among defi protocol companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
Coverage
Every country. Country and city lists for defi protocol companies are linked below.
What qualifies
Companies worldwide whose own description of what they do matches “defi protocol companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names defi protocol companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among defi protocol companies, and records with no verified work email.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 443 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Defi protocol companies by location

1 lists · largest first

Every Defi protocol companies list RevenueBase publishes, by country and city. Counts are matching companies in each list as of its own refresh date.

Countries

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names defi protocol companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many defi protocol companies are there worldwide?

RevenueBase identified 444 defi protocol companies worldwide as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Uniswap, headquartered in New York, tops this list with the largest team on record.

Which country has the most defi protocol companies?

The United States leads with 73 companies. Every defi protocol companies list by country and city is linked on this page.

Which city has the most defi protocol companies?

San Francisco leads with 21 headquartered companies, followed by London (17) and Singapore (13).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 443 verified decision-maker contacts tracked across these 444 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.