Company lists · Data refreshed November 2026

Top 25 Enzyme replacement therapy companies worldwide

RevenueBase identified 299 company matches for enzyme replacement therapy companies worldwide as of November 2026 and tracks 22,184 professional contacts across them, including 10,054 with verified work emails. The United States is the largest market and Boca Raton the largest hub.

This list covers company matches for enzyme replacement therapy companies worldwide, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed November 6, 2026. Country and city lists for enzyme replacement therapy companies follow the table.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Nov 6, 2026 How this list was built
299Companies
22,184Contacts tracked
10,054Verified emails
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The 25 largest enzyme replacement therapy companies worldwide

Ranked by team size
Top 25 of 299 company matches for enzyme replacement therapy companies worldwide, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Nov 6, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchBoston, MA, United StatesHQ recorded Nov 6, 20261,001-5,0006,399 contacts →

Exact match

“Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
2Exact matchBridgewater Township, NJ, United StatesHQ recorded Nov 6, 20261,001-5,0001,700 contacts →

Exact match

“Insmed is a people-rst global biopharmaceutical company striving to deliver rst- and best-in-class therapies to transform the lives of patients facing serious diseases.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
3Exact matchNovato, United StatesHQ recorded Nov 6, 20261,001-5,0001,639 contacts →

Exact match

“Leading with purpose.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
4Exact matchPalo Alto, CA, United StatesHQ recorded Nov 6, 2026501-1,0001,021 contacts →

Exact match

“We exist to bring transformative medicines to people living with genetic conditions.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
5Exact matchMonaco, United StatesHQ recorded Nov 6, 20261,001-5,000917 contacts →

Exact match

“At Besins Healthcare, we put patients at the centre of everything we do, every single day.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
6Exact matchPrinceton, NJ, United StatesHQ recorded Nov 6, 2026501-1,000582 contacts →

Exact match

“Amicus Therapeutics is now part of BioMarin Pharmaceutical Inc, a leading, global rare disease biotechnology company focused on delivering medicines for people living with…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
7Exact matchSan Diego, CA, United StatesHQ recorded Nov 6, 2026201-500536 contacts →

Exact match

“Our mission is to identify, develop and deliver life-changing therapies to people living with rare disease.#InRareForLife Community Guidelines…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
8Exact matchFoster City, CA, United StatesHQ recorded Nov 6, 2026201-500431 contacts →

Exact match

“Mirum Pharmaceuticals is a leading rare disease company with a global footprint of approved products and a broad pipeline of investigational medicines.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
9Exact matchPleasant Hill, CA, United StatesHQ recorded Nov 6, 202651-200403 contacts →

Exact match

“New U Life® is THE hormone health company!”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
10Exact matchWaltham, MA, United StatesHQ recorded Nov 6, 2026201-500336 contacts →

Exact match

“Sobi is an international specialty healthcare company dedicated to developing treatments and extensive patient support networks for people with rare and difficult to treat…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
11Exact matchBeccar, ArgentinaHQ recorded Nov 6, 2026201-500234 contacts →

Exact match

“Focused on complex therapies and orphan diseases, Varifarma is a company which is devoted to improving the patients' quality of life.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
12Exact matchCambridge, United KingdomHQ recorded Nov 6, 202651-200229 contacts →

Exact match

“We’re committed to supporting patients and their caregivers in every way we can.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
13Exact matchMilan, ItalyHQ recorded Nov 6, 2026201-500196 contacts →

Exact match

“Founded in 1996, the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) is a joint venture between Fondazione Telethon, a major Italian charity funding research on rare…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
14Exact matchCoral Gables, FL, United StatesHQ recorded Nov 6, 202651-200179 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
15Exact matchBoca Raton, FL, United StatesHQ recorded Nov 6, 2026n/a168 contacts →

Exact match

“As a central aspect of men’s and women’s health, hormones play a key role in balanced emotions, energy, metabolism, and more especially as we age.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
16Exact matchParamus, NJ, United StatesHQ recorded Nov 6, 202651-200163 contacts →

Exact match

“NS Pharma, Inc.(NSP) is a biopharmaceutical leader in delivering life-changing care to people living with complex, rare diseases, backed by over 100 years of Nippon Shinyaku Co.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
17Exact matchWaltham, MA, United StatesHQ recorded Nov 6, 202651-200101 contacts →

Exact match

“Alcresta Therapeutics is dedicated to developing and commercializing novel, enzyme-based products designed to address challenges faced by people living with gastrointestinal…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
18Exact matchBoston, MA, United StatesHQ recorded Nov 6, 202651-20089 contacts →

Exact match

“We are a fully integrated, commercial-stage biopharmaceutical company driving progress for people living with rare immune disorders.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
19Exact matchAustin, TX, United StatesHQ recorded Nov 6, 202611-5088 contacts →

Exact match

“Doctor prescribed treatments for menopause symptoms.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
20Exact matchBogotá, ColombiaHQ recorded Nov 6, 202651-20079 contacts →

Exact match

“Valentech is a specialized Latin American healthcare company focused on enabling patient access to innovative therapies for high‑burden rare diseases across Central and South…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
21Exact matchConcord, MA, United StatesHQ recorded Nov 6, 202651-20073 contacts →

Exact match

“ITF Therapeutics is the US-based rare disease division of Italfarmaco S.p.A.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
22Exact matchPhiladelphia, PA, United StatesHQ recorded Nov 6, 202651-20070 contacts →

Exact match

“GEMMABio, a new therapeutics company, will serve as the research and innovation arm to speed the research of and global access to life-changing advanced therapies for those living…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
23Exact matchMadrid, SpainHQ recorded Nov 6, 202651-20061 contacts →

Exact match

“Sobi es una compañía biofarmacéutica internacional que trabaja cada día para ofrecer terapias y servicios innovadores que mejoren la vida de las personas con enfermedades raras y…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
24Exact matchLake Forest, IL, United StatesHQ recorded Nov 6, 202651-20052 contacts →

Exact match

“Jaguar Gene Therapy, LLC is dedicated to accelerating breakthroughs in gene therapy for patients suffering from severe genetic diseases including those that impact sizeable…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
25Exact matchAmsterdam, NetherlandsHQ recorded Nov 6, 202611-5041 contacts →

Exact match

“Scenic Biotech's lead program addresses lysosomal storage disorders and neurodegeneration.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase

Showing 25 of 299 enzyme replacement therapy companies worldwide

See the full list, filter by size, metro and specialty, and access 10,054 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Enzyme replacement therapy companies worldwide at a glance

As of Nov 6, 2026
45.3%Verified-email coverage
74.2Average contacts per company
11-50Median size (employees)
2.0%Largest-city concentration · Boca Raton
Nov 6, 2026Page data refreshed

Companies by employee count

1-10
136
11-50
104
51-200
33
201-500
11
501-1,000
4
1,001-5,000
8
10001+
1

Email recency is reported on each country list linked below.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
Coverage
Every country. Country and city lists for enzyme replacement therapy companies are linked below.
What qualifies
Company records worldwide whose business descriptions match “enzyme replacement therapy companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 10,054 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on November 6, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Enzyme replacement therapy companies by location

1 lists · largest first

Every Enzyme replacement therapy companies list RevenueBase publishes, by country and city. Counts are matching companies in each list as of its own refresh date.

Countries

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “enzyme replacement therapy companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many enzyme replacement therapy companies are there worldwide?

RevenueBase identified 299 company matches for enzyme replacement therapy companies worldwide as of November 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Alexion Pharmaceuticals, INC tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which country has the most enzyme replacement therapy companies?

The United States leads with 171 companies. Every enzyme replacement therapy companies list by country and city is linked on this page.

Which city has the most enzyme replacement therapy companies?

Boca Raton leads with 6 company records, followed by Boston (5) and Plano (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 10,054 professional contacts with verified work emails tracked across these 299 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on November 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.