Company lists · Data refreshed September 2026

Top 25 Enzyme replacement therapy companies worldwide

RevenueBase identified 219 enzyme replacement therapy companies worldwide as of September 2026 and tracks 3,676 professional contacts across them, including 1,249 with verified work emails. The United States is the largest market and Boca Raton the largest hub.

This list covers enzyme replacement therapy companies worldwide, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026. Country and city lists for enzyme replacement therapy companies follow the table.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
219Companies
3,676Contacts tracked
1,249Verified emails
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The 25 largest enzyme replacement therapy companies worldwide

Ranked by team size
Top 25 of 219 enzyme replacement therapy companies worldwide, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to enzyme replacement therapy companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceMonaco, United StatesHQ checked Sep 19, 20261,001-5,000838 contacts →

Indirect evidence

“At Besins Healthcare, we put patients at the centre of everything we do, every single day.”

Source: RevenueBase Database · checked Sep 19, 2026
2Indirect evidencePleasant Hill, CA, United StatesHQ checked Sep 19, 202651-200389 contacts →

Indirect evidence

“New U Life® is THE hormone health company!”

Source: RevenueBase Database · checked Sep 19, 2026
3Indirect evidenceWaltham, MA, United StatesHQ checked Sep 19, 2026201-500326 contacts →

Indirect evidence

“Sobi is an international specialty healthcare company dedicated to developing treatments and extensive patient support networks for people with rare and difficult to treat…”

Source: RevenueBase Database · checked Sep 19, 2026
4Partial evidenceBeccar, ArgentinaHQ checked Sep 19, 2026201-500217 contacts →

Partial evidence

“Focused on complex therapies and orphan diseases, Varifarma is a company which is devoted to improving the patients' quality of life.”

Source: RevenueBase Database · checked Sep 19, 2026
5Indirect evidenceBoca Raton, FL, United StatesHQ checked Sep 19, 2026n/a162 contacts →

Indirect evidence

“As a central aspect of men’s and women’s health, hormones play a key role in balanced emotions, energy, metabolism, and more especially as we age.”

Source: RevenueBase Database · checked Sep 19, 2026
6Strong evidenceWaltham, MA, United StatesHQ checked Sep 19, 202651-20083 contacts →

Strong evidence

“Alcresta Therapeutics is dedicated to developing and commercializing novel, enzyme-based products designed to address challenges faced by people living with gastrointestinal…”

Source: RevenueBase Database · checked Sep 19, 2026
7Indirect evidenceAustin, TX, United StatesHQ checked Sep 19, 202611-5074 contacts →

Indirect evidence

“Doctor prescribed treatments for menopause symptoms.”

Source: RevenueBase Database · checked Sep 19, 2026
8Strong evidenceTromsø, NorwayHQ checked Sep 19, 202651-20048 contacts →

Strong evidence

“ArcticZymes Technologies ASA (OSE: AZT): Enzymes Engineered for Breakthroughs, We deliver high-performance enzymes that power molecular diagnostics, gene therapy, and vaccine…”

Source: RevenueBase Database · checked Sep 19, 2026
9Partial evidenceBoston, MA, United StatesHQ checked Sep 19, 202611-5048 contacts →

Partial evidence

“We are a biopharmaceutical company specializing in the development of novel therapeutics to treat rare metabolic diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
10Indirect evidenceCary, NC, United StatesHQ checked Sep 19, 202611-5034 contacts →

Indirect evidence

“Most people are told their labs are normal while they're still exhausted, foggy, and feeling like a stranger in their own body.”

Source: RevenueBase Database · checked Sep 19, 2026
11Partial evidenceNatick, MA, United StatesHQ checked Sep 19, 202611-5026 contacts →

Partial evidence

“Anagram is a clinical stage company leveraging proprietary enzyme technologies and expertise in gastrointestinal diseases to solve complex problems and advance a pipeline of…”

Source: RevenueBase Database · checked Sep 19, 2026
12Strong evidenceJupiter, FL, United StatesHQ checked Sep 19, 202651-20025 contacts →

Strong evidence

“Renew Vitality is a nationwide leader in hormone replacement therapy, peptide therapy, weight loss programs, sexual health, and performance supplements.”

Source: RevenueBase Database · checked Sep 19, 2026
13Indirect evidenceAustin, TX, United StatesHQ checked Sep 19, 20261-1025 contacts →

Indirect evidence

“We help men boost their testosterone up to a healthy, normal level using testosterone cream.”

Source: RevenueBase Database · checked Sep 19, 2026
14Partial evidenceSan Carlos, CA, United StatesHQ checked Sep 19, 20261-1024 contacts →

Partial evidence

“Glycomine is developing orphan drugs for serious rare disorders of metabolism and protein misfolding for which no other therapeutic options exist.”

Source: RevenueBase Database · checked Sep 19, 2026
15Indirect evidenceUnited StatesHQ checked Sep 19, 202611-5020 contacts →

Indirect evidence

“At The HRT Club we make hormone treatments affordable and accessible to all.”

Source: RevenueBase Database · checked Sep 19, 2026
16Strong evidenceSt Louis, MO, United StatesHQ checked Sep 19, 20261-1018 contacts →

Strong evidence

“M6P Therapeutics is developing the next-generation enzyme replacement and gene therapies for lysosomal storage disorders.”

Source: RevenueBase Database · checked Sep 19, 2026
17Indirect evidenceUtrecht, NetherlandsHQ checked Sep 19, 202611-5016 contacts →

Indirect evidence

“AM-Pharma’s purpose is to save and improve the lives of patients confronted with severe medical conditions.”

Source: RevenueBase Database · checked Sep 19, 2026
18Strong evidencePlano, TX, United StatesHQ checked Sep 19, 202611-5016 contacts →

Strong evidence

“Purepell is a premier provider of turnkey Bioidentical Hormone Replacement Therapy (BHRT) solutions for medical practices.”

Source: RevenueBase Database · checked Sep 19, 2026
19Indirect evidenceWest Palm Beach, FL, United StatesHQ checked Sep 19, 202611-5015 contacts →

Indirect evidence

“At Hormone Logics we have one combined goal, to get you looking your best and feeling in your 20s again using bio identical hormones.”

Source: RevenueBase Database · checked Sep 19, 2026
20Strong evidenceHudson, FL, United StatesHQ checked Sep 19, 202611-5015 contacts →

Strong evidence

“Hormone Replacement Therapy for both Men and Women through the ease of TeleMedicine.”

Source: RevenueBase Database · checked Sep 19, 2026
21Partial evidenceUnited StatesHQ checked Sep 19, 202611-5015 contacts →

Partial evidence

“Bionourisso was founded in 2012 by healthcare professionals who visualized the need for a laboratory in Mexico to meet the growing need for natural hormone replacement products…”

Source: RevenueBase Database · checked Sep 19, 2026
22Partial evidenceFitchburg, WI, United StatesHQ checked Sep 19, 20261-1014 contacts →

Partial evidence

“JangoBio is developing regenerative therapies to reverse hormone imbalances associated with aging and thereby mitigate the risk of developing a wide range of age-related diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
23Indirect evidenceUnited StatesHQ checked Sep 19, 202651-20012 contacts →

Indirect evidence

“RLC Labs is a pioneer and industry leader in the field of hypothyroid treatment.”

Source: RevenueBase Database · checked Sep 19, 2026
24Indirect evidenceJupiter, FL, United StatesHQ checked Sep 19, 202611-5011 contacts →

Indirect evidence

“At LifeXMD we take pride in providing you with personalized, high quality services designed to help you achieve your unique health and fitness goals.”

Source: RevenueBase Database · checked Sep 19, 2026
25Strong evidenceTigard, OR, United StatesHQ checked Sep 19, 202611-5011 contacts →

Strong evidence

“Full Potential HRT Clinic provides Portland, Oregon and Seattle, Washington with unrivaled state-of-the-art testosterone replacement therapy (TRT), human growth hormone (HGH)…”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 219 enzyme replacement therapy companies worldwide

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Enzyme replacement therapy companies worldwide at a glance

As of Sep 19, 2026
34.0%Verified-email coverage
16.8Average contacts per company
1-10Median size (employees)
1.8%Largest-city concentration · Boca Raton
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
115
11-50
75
51-200
21
201-500
4
501-1,000
1
1,001-5,000
1
10001+
1

Email recency is reported on each country list linked below.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among enzyme replacement therapy companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
Coverage
Every country. Country and city lists for enzyme replacement therapy companies are linked below.
What qualifies
Companies worldwide whose own description of what they do matches “enzyme replacement therapy companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names enzyme replacement therapy companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among enzyme replacement therapy companies, and records with no verified work email.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,249 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Enzyme replacement therapy companies by location

1 lists · largest first

Every Enzyme replacement therapy companies list RevenueBase publishes, by country and city. Counts are matching companies in each list as of its own refresh date.

Countries

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names enzyme replacement therapy companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many enzyme replacement therapy companies are there worldwide?

RevenueBase identified 219 enzyme replacement therapy companies worldwide as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Besins Healthcare, headquartered in Worldwide, tops this list with the largest team on record.

Which country has the most enzyme replacement therapy companies?

The United States leads with 133 companies. Every enzyme replacement therapy companies list by country and city is linked on this page.

Which city has the most enzyme replacement therapy companies?

Boca Raton leads with 4 headquartered companies, followed by Austin (3) and Boston (3).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,249 verified decision-maker contacts tracked across these 219 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.