Company lists · Data refreshed September 2026

Top 25 Biotherapeutics companies based in Waltham, United States

Name: Biotherapeutics companies based in Waltham, United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 19, 2026 40 companies tracked

RevenueBase identified 40 biotherapeutics companies headquartered in Waltham, United States as of September 2026 and tracks 5,218 professional contacts across them, including 3,580 with verified work emails. Across the United States, San Diego is the largest hub for this category (187 companies); Waltham has 40.

This list covers biotherapeutics companies headquartered in Waltham, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review

40Companies

5,218Contacts tracked

3,580Verified emails

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The 25 largest biotherapeutics companies based in Waltham, United States

Ranked by team size

Top 25 of 40 biotherapeutics companies based in Waltham, United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to biotherapeutics companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Repligen Corporation	Strong evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	1,001-5,000	1,254 contacts →
	Strong evidence “Repligen, a global, bioprocessing-focused life sciences company, provides innovative solutions for the advancement of biotherapeutic manufacturing.” Source: RevenueBase Database · checked Sep 19, 2026
2	Apellis Pharmaceuticals	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	501-1,000	823 contacts →
	Indirect evidence “Apellis is now part of Biogen.” Source: RevenueBase Database · checked Sep 19, 2026
3	Ardelyx, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	201-500	497 contacts →
	Indirect evidence “Ardelyx is a commercial-stage biopharmaceutical company focused on the development and commercialization of innovative medicines that meet significant unmet medical needs.” Source: RevenueBase Database · checked Sep 19, 2026
4	Elevatebio	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	201-500	361 contacts →
	Indirect evidence “ElevateBio is a technology-driven advanced therapy contract development and manufacturing organization (CDMO) powering the creation of life-transforming therapies.” Source: RevenueBase Database · checked Sep 19, 2026
5	SOBI	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	201-500	326 contacts →
	Indirect evidence “Sobi is an international specialty healthcare company dedicated to developing treatments and extensive patient support networks for people with rare and difficult to treat…” Source: RevenueBase Database · checked Sep 19, 2026
6	Viridian Therapeutics, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	201-500	282 contacts →
	Indirect evidence “Viridian is a biopharmaceutical company focused on engineering and developing potential best-in-class medicines for patients with serious and rare diseases.” Source: RevenueBase Database · checked Sep 19, 2026
7	Tscan Therapeutics	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	190 contacts →
	Indirect evidence “TScan is dedicated to creating life-changing T cell therapies for patients by unleashing the untapped potential of the human immune system.” Source: RevenueBase Database · checked Sep 19, 2026
8	Zenas Biopharma	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	159 contacts →
	Indirect evidence “Zenas is a clinical-stage global biopharmaceutical company committed to becoming a leader in the development and commercialization of transformative therapies for patients living…” Source: RevenueBase Database · checked Sep 19, 2026
9	Visterra INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	146 contacts →
	Indirect evidence “Visterra is a clinical stage biotechnology company committed to developing innovative antibody-based therapies for the treatment of patients with kidney diseases and other…” Source: RevenueBase Database · checked Sep 19, 2026
10	Ventus Therapeutics	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	101 contacts →
	Indirect evidence “At Ventus, we are pioneering a unique approach to structure-based drug discovery to address biologically validated, but difficult-to-drug targets.” Source: RevenueBase Database · checked Sep 19, 2026
11	Spyre Therapeutics	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	96 contacts →
	Indirect evidence “Spyre Therapeutics is a clinical-stage biotechnology company that aims to create next-generation inflammatory bowel disease (IBD) and other immune-mediated disease products by…” Source: RevenueBase Database · checked Sep 19, 2026
12	Dragonfly Therapeutics, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	95 contacts →
	Indirect evidence “Dragonfly Therapeutics is a clinical-stage biopharmaceutical company committed to discovering, developing and commercializing therapies that use its novel multispecific antibody…” Source: RevenueBase Database · checked Sep 19, 2026
13	Xilio Therapeutics, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	89 contacts →
	Indirect evidence “Xilio is a Waltham, Massachusetts-based clinical-stage biopharmaceutical company focused on defeating cancer.” Source: RevenueBase Database · checked Sep 19, 2026
14	Upstream BIO	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	62 contacts →
	Indirect evidence “We are advancing verekitug, a clinical-stage monoclonal antibody targeting an upstream driver of inflammatory response.” Source: RevenueBase Database · checked Sep 19, 2026
15	Mural Oncology	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	57 contacts →
	Indirect evidence “We know that drug development is both an art and a science.” Source: RevenueBase Database · checked Sep 19, 2026
16	Paragon Therapeutics, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	53 contacts →
	Indirect evidence Source: RevenueBase Database · checked Sep 19, 2026
17	Mustang BIO	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	n/a	52 contacts →
	Indirect evidence “Mustang Bio, Inc.” Source: RevenueBase Database · checked Sep 19, 2026
18	Orionis Biosciences	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	50 contacts →
	Indirect evidence “Orionis Biosciences is a life sciences company pioneering technological innovation in genome-scale drug discovery and tunable molecular design of novel therapeutic drug modalities.” Source: RevenueBase Database · checked Sep 19, 2026
19	Crescent Biopharma	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	48 contacts →
	Indirect evidence “Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients.” Source: RevenueBase Database · checked Sep 19, 2026
20	Mythic Therapeutics, INC	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	39 contacts →
	Indirect evidence “Mythic Therapeutics is a product-platform company that is pioneering a powerful new approach to improving the effectiveness of antibody-drug conjugates (ADCs) and other…” Source: RevenueBase Database · checked Sep 19, 2026
21	Sironax	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	51-200	36 contacts →
	Indirect evidence “Sironax is a clinical-stage biotechnology company developing transformative therapies for neurodegenerative, inflammatory, immunologic, and metabolic diseases.” Source: RevenueBase Database · checked Sep 19, 2026
22	Dynamicure Biotechnology	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	29 contacts →
	Indirect evidence “Driven by science and passionate about advancing patient care, DynamiCure is translating breakthrough insights on immuno-normalization into a pipeline of innovative antibody…” Source: RevenueBase Database · checked Sep 19, 2026
23	Immunitas Therapeutics	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	29 contacts →
	Indirect evidence “Immunitas is committed to discovering and developing novel, differentiated therapeutics for patients with cancer and autoimmune diseases.” Source: RevenueBase Database · checked Sep 19, 2026
24	Bioverativ, A Sanofi Company	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	201-500	29 contacts →
	Indirect evidence “Bioverativ, a Sanofi company, is dedicated to transforming the lives of people with hemophilia and other rare blood disorders through world-class research, development, and…” Source: RevenueBase Database · checked Sep 19, 2026
25	Bonito Biosciences	Indirect evidence	Waltham, MA, United StatesHQ checked Sep 19, 2026	11-50	26 contacts →
	Indirect evidence “Bonito is building the data foundation for programmable oligotherapeutic delivery to any cell or tissue type.” Source: RevenueBase Database · checked Sep 19, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: biotherapeutics companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names biotherapeutics companies.
Partial evidence: Its own public description names part of biotherapeutics companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name biotherapeutics companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 40 biotherapeutics companies based in Waltham, United States

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Biotherapeutics companies based in Waltham, United States at a glance

As of Sep 19, 2026

68.6%Verified-email coverage

130.4Average contacts per company

51-200Median size (employees)

Sep 19, 2026Page data refreshed

Companies by employee count

1-10

11-50

51-200

201-500

501-1,000

1,001-5,000

Email recency for this list is measured across the whole United States list rather than for Waltham, so it is reported there. Company counts and contact totals on this page are exact for Waltham, over 40 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotherapeutics companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in Waltham, United States whose own description of what they do matches “biotherapeutics companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotherapeutics companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among biotherapeutics companies, and records with no verified work email. Companies headquartered outside Waltham are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 3,580 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Biotherapeutics companies by metro in the United States

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotherapeutics companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many biotherapeutics companies are there based in Waltham, United States?

RevenueBase identified 40 biotherapeutics companies headquartered in Waltham, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Repligen Corporation, headquartered in Waltham, tops this list with the largest team on record.

Which city in the United States has the most biotherapeutics companies?

San Diego leads the United States with 187 headquartered companies, followed by Cambridge (154) and Boston (111). Waltham has 40.

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 3,580 verified decision-maker contacts tracked across these 40 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.