Company lists · Data refreshed September 2026

Top 25 Biotherapeutics companies based in South San Francisco, United States

Name: Biotherapeutics companies based in South San Francisco, United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 7, 2026 55 companies tracked

RevenueBase identified 55 biotherapeutics companies headquartered in South San Francisco, United States as of September 2026 and tracks 20,431 professional contacts across them, including 9,408 with verified work emails. San Diego is the largest hub.

This list covers biotherapeutics companies headquartered in South San Francisco, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 7, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 7, 2026 86% judged on-target in blind review

55Companies

20,431Contacts tracked

9,408Verified emails

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The 25 largest biotherapeutics companies based in South San Francisco, United States

Ranked by team size

Top 25 of 55 biotherapeutics companies based in South San Francisco, United States, ranked by team size, largest first. Data refreshed Sep 7, 2026. RevenueBase Smart Search rates how each company's information relates to biotherapeutics companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Genentech	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	10001+	17,217 contacts →
	“About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions.” Source: company website · checked Sep 7, 2026
2	Rigel Pharmaceuticals INC	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	291 contacts →
	“Rigel Pharmaceuticals, Inc, is a biotechnology company dedicated to discovering, developing and providing novel small molecule drugs that significantly improve the lives of…” Source: company website · checked Sep 7, 2026
3	Sutro Biopharma, INC	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	201-500	282 contacts →
	“Sutro Biopharma, Inc, is relentlessly focused on the discovery and development of precisely designed cancer therapeutics to transform what science can do for patients.” Source: company website · checked Sep 7, 2026
4	Onyx Pharmaceuticals, Inc., An Amgen Subsidiary	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	501-1,000	223 contacts →
	“Formerly based in South San Francisco, California, Onyx Pharmaceuticals was engaged in the development and commercialization of innovative therapies for improving the lives of…” Source: company website · checked Sep 7, 2026
5	Cellares	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	201-500	220 contacts →
	“Cellares is the first Integrated Development and Manufacturing Organization (IDMO), providing global cell therapy development and manufacturing services through an Industry 4.0…” Source: company website · checked Sep 7, 2026
6	Alumis	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	125 contacts →
	“At Alumis, our goal is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies.” Source: company website · checked Sep 7, 2026
7	Rapt Therapeutics	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	123 contacts →
	“RAPT is a clinical-stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing novel therapies for patients living with inflammatory…” Source: company website · checked Sep 7, 2026
8	NGM Biopharmaceuticals	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	116 contacts →
	“NGM Bio is a biopharmaceutical company focused on discovering and developing novel, life-changing medicines for people whose health and lives have been disrupted by disease.” Source: company website · checked Sep 7, 2026
9	Cytomx Therapeutics	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	100 contacts →
	“CytomX Therapeutics, Inc.” Source: company website · checked Sep 7, 2026
10	Circle Pharma, INC	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	75 contacts →
	“Circle Pharma initiated operations in June 2014 with seed funding from Pfizer, Inc.” Source: company website · checked Sep 7, 2026
11	Senti Biosciences	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	73 contacts →
	“Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable.” Source: company website · checked Sep 7, 2026
12	Trexbio	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	59 contacts →
	“TRexBio is a clinical-stage biotechnology company discovering and developing immunoregulatory medicines based on tissue Treg biology by leveraging cutting-edge computational…” Source: company website · checked Sep 7, 2026
13	ALX Oncology	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	58 contacts →
	“ALX Oncology (Nasdaq: ALXO) is a clinical-stage biotechnology company advancing therapies that boost the immune system to treat cancer and extend patients’ lives.” Source: company website · checked Sep 7, 2026
14	Portola Pharmaceuticals	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	201-500	47 contacts →
	“We are focused on the discovery, development and commercialization of novel therapeutics that could significantly advance the fields of thrombosis and other hematologic conditions.” Source: company website · checked Sep 7, 2026
15	Star Therapeutics	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	45 contacts →
	“Star Therapeutics is a biotechnology company focused on the discovery and development of life-changing therapies for diseases with significant unmet need.” Source: company website · checked Sep 7, 2026
16	Gordian Biotechnology	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	43 contacts →
	“Our mission is to cure age-related disease by moving successful therapeutics toward clinical trials within months, not years.#CreatingTime” Source: company website · checked Sep 7, 2026
17	Remegen Biosciences	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	36 contacts →
	“RemeGen Biosciences is a biopharmaceutical company, focusing on the discovery and development of innovative medicines for the treatment of cancer and autoimmune diseases, based in…” Source: company website · checked Sep 7, 2026
18	Centivax	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	34 contacts →
	“Smash the mutants” Source: company website · checked Sep 7, 2026
19	3t Biosciences	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	32 contacts →
	“3T is an immunotherapy company developing next-generation, transformative therapies for the treatment of solid tumors and other immune-mediated diseases in broad patient…” Source: company website · checked Sep 7, 2026
20	Lyterian Therapeutics	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	31 contacts →
	“Lyterian Therapeutics derives its name from the Greek word λυτήριος or lutḗrios, that defines the termination, healing, or end of disease.” Source: company website · checked Sep 7, 2026
21	Atreca, INC	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	29 contacts →
	“Atreca is a biotechnology company that develops novel therapeutics through a deep understanding of the human immune response, with a focus on innovative novel cancer…” Source: company website · checked Sep 7, 2026
22	Calithera Biosciences	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	51-200	28 contacts →
	“Calithera Biosciences is a clinical-stage biopharmaceutical company pioneering the discovery and development of targeted therapies that disrupt cellular metabolic pathways to…” Source: company website · checked Sep 7, 2026
23	Moonwalk Biosciences	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	25 contacts →
	“Moonwalk Biosciences is pioneering novel therapeutics in adipose biology and tissue, driven by deep genetic and epigenetic evidence and insights.” Source: company website · checked Sep 7, 2026
24	Tizona Therapeutics, INC	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	11-50	22 contacts →
	“Tizona Therapeutics, Inc, is an immunology company harnessing the power of the immune system to develop treatments for cancer and autoimmune diseases.” Source: company website · checked Sep 7, 2026
25	Apertor Pharmaceuticals	Indirect evidence	South San Francisco, CA, United StatesHQ checked Sep 7, 2026	1-10	18 contacts →
	“At Apertor we have developed a new class of therapeutics to address one of the toughest challenges in drug discovery, selective disruption of disease-causing protein-protein…” Source: company website · checked Sep 7, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: biotherapeutics companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names biotherapeutics companies.
Partial evidence: Its own public description names part of biotherapeutics companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name biotherapeutics companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 55 biotherapeutics companies based in South San Francisco, United States

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Biotherapeutics companies based in South San Francisco, United States at a glance

As of Sep 7, 2026

46.0%Verified-email coverage

371.5Average contacts per company

11-50Median size (employees)

321.8%Largest-city concentration · San Diego

Sep 7, 2026Page data refreshed

Companies by employee count

1-10

11-50

51-200

201-500

501-1,000

10001+

Email recency for this list is measured across the whole United States list rather than this city, so it is reported there. Company counts and contact totals on this page are exact for South San Francisco, over 55 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotherapeutics companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in South San Francisco, United States whose own description of what they do matches “biotherapeutics companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotherapeutics companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among biotherapeutics companies, and records with no verified work email. Companies headquartered outside South San Francisco are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 9,408 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 7, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Biotherapeutics companies by metro in the United States

Biotherapeutics companies in San Diego177
Biotherapeutics companies in Cambridge154
Biotherapeutics companies in Boston111
Biotherapeutics companies in New York83
Biotherapeutics companies in San Francisco61
Biotherapeutics companies in South San Francisco55
Biotherapeutics companies in Seattle47
Biotherapeutics companies in Houston46
Biotherapeutics companies in Waltham40
Biotherapeutics companies in Durham35
Biotherapeutics companies in Philadelphia35
Biotherapeutics companies in Chicago34
Biotherapeutics companies in Los Angeles30
Biotherapeutics companies in Rockville30

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotherapeutics companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many biotherapeutics companies are there based in South San Francisco, United States?

RevenueBase identified 55 biotherapeutics companies headquartered in South San Francisco, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Genentech, headquartered in South San Francisco, tops this list with the largest team on record.

Which city has the most biotherapeutics companies?

San Diego leads with 177 headquartered companies, followed by Cambridge (154) and Boston (111).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 9,408 verified decision-maker contacts tracked across these 55 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 7, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.