Company lists · Data refreshed September 2026

Top 15 Biotech startups based in Boston, United States

RevenueBase identified 41 biotech startups headquartered in Boston, United States as of September 2026 and tracks 876 professional contacts across them, including 164 with verified work emails. San Francisco is the largest hub.

This list covers biotech startups headquartered in Boston, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
41Companies
876Contacts tracked
164Verified emails
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The 15 largest biotech startups based in Boston, United States

Ranked by team size
Top 15 of 41 biotech startups based in Boston, United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to biotech startups: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceBoston, United StatesHQ checked Sep 16, 202651-200424 contacts →

Partial evidence

“Nucleate is a free, trainee-led 501(c)(3) non-profit organization dedicated to empowering the next generation of biotech leaders.”

Source: RevenueBase Database · checked Sep 16, 2026
2Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5095 contacts →

Partial evidence

“MPM BioImpact is a world-leading biotechnology investment firm with nearly three decades of experience creating and investing in companies that seek to translate scientific…”

Source: RevenueBase Database · checked Sep 16, 2026
3Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5055 contacts →

Indirect evidence

“Spear Bio, founded in 2021, is a well-funded and rapidly growing start-up headquartered in Woburn, Massachusetts.”

Source: RevenueBase Database · checked Sep 16, 2026
4Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5039 contacts →

Partial evidence

“Boston-based AI Proteins is a biotech company on a mission to re-imagine protein therapeutics with a novel approach for designing entirely new proteins.”

Source: RevenueBase Database · checked Sep 16, 2026
5Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5032 contacts →

Partial evidence

“We work with biotech innovators at all stages of growth and development, whether they are launching anew or advancing a potentially transformative medicine through regulatory…”

Source: RevenueBase Database · checked Sep 16, 2026
6Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5021 contacts →

Indirect evidence

“The first chapter of Nucleate.”

Source: RevenueBase Database · checked Sep 16, 2026
7Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-109 contacts →

Partial evidence

“Xontogeny (zon-TOJ-uh-nee) is a biotech aggregator with a differentiated business model to support the accelerated development of life science technologies in the pursuit of…”

Source: RevenueBase Database · checked Sep 16, 2026
8Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-106 contacts →

Partial evidence

“Multi-stage venture capital firm building and investing in disruptive biotechnology companies.”

Source: RevenueBase Database · checked Sep 16, 2026
9Strong evidenceBoston, MA, United StatesHQ checked Sep 16, 202651-2005 contacts →

Strong evidence

“A novel and effective investment vehicle aimed at bridging the infamous biotech startup “valley of death” and generating high returns, while furthering the development of medical…”

Source: RevenueBase Database · checked Sep 16, 2026
10Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-105 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 16, 2026
11Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-103 contacts →

Partial evidence

“Our goal at Twinning Edge is to enable start-ups and small businesses in the high-tech, biotech, health-tech, medtech and non-profit spaces to achieve their potential by creating…”

Source: RevenueBase Database · checked Sep 16, 2026
12Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-103 contacts →

Partial evidence

“Polaris is a startup recruitment platform bridging various early-stage ventures and business graduate students who are interested in joining startups.”

Source: RevenueBase Database · checked Sep 16, 2026
13Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 20261-103 contacts →

Partial evidence

“Petri is a new approach for funding formation-stage startups at the intersection of biology and engineering.”

Source: RevenueBase Database · checked Sep 16, 2026
14Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-502 contacts →

Indirect evidence

“Home of Tufts Launchpad | Biolabs, Eisai Innovation Center | Biolabs and BioLabs Watertown.”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidenceBoston, MA, United StatesHQ checked Sep 16, 202651-2001 contacts →

Indirect evidence

“Manus is the world’s leading bioalternatives scale-up platform.”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 15 of 41 biotech startups based in Boston, United States

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Biotech startups based in Boston, United States at a glance

As of Sep 16, 2026
18.7%Verified-email coverage
21.4Average contacts per company
11-50Median size (employees)
112.2%Largest-city concentration · San Francisco
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
20
11-50
16
51-200
3
201-500
2

Email recency for this list is measured across the whole United States list rather than for Boston, so it is reported there. Company counts and contact totals on this page are exact for Boston, over 41 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among biotech startups, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in Boston, United States whose own description of what they do matches “biotech startups”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names biotech startups), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among biotech startups, and records with no verified work email. Companies headquartered outside Boston are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 164 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Biotech startups by metro in the United States

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names biotech startups, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many biotech startups are there based in Boston, United States?

RevenueBase identified 41 biotech startups headquartered in Boston, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Nucleate, headquartered in Boston, tops this list with the largest team on record.

Which city has the most biotech startups?

San Francisco leads with 46 headquartered companies, followed by Boston (41) and New York (33).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 164 verified decision-maker contacts tracked across these 41 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.