Company lists · Data refreshed September 2026
Top 23 Venture capital firms focused on deep tech companies based in San Diego, United States
RevenueBase identified 41 venture capital firms focused on deep tech companies headquartered in San Diego, United States as of September 2026 and tracks 398 professional contacts across them, including 82 with verified work emails. Across the United States, San Francisco is the largest hub for this category (522 companies); San Diego has 41.
This list covers venture capital firms focused on deep tech companies headquartered in San Diego, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 29, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 23 largest venture capital firms focused on deep tech companies based in San Diego, United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 15 contacts → | ||||
Partial evidence “Harpoon is America’s venture firm.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 2 | 13 contacts → | ||||
Strong evidence “Avalon BioVentures is a biotech venture capital firm that builds on Avalon’s 40-year success in pursuing disruptive ideas to improve life.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 3 | 10 contacts → | ||||
Partial evidence “Our Mission: Is revolutionizing venture investing through the discipline of venture science.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 4 | 9 contacts → | ||||
Partial evidence “Recognized as a 2022 Emerging 50 VC and 2023 Top 25 Founder’s Choice VC, Spark Growth Ventures is a community oriented, early & mid stage, vertical-agnostic, technology venture…” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 5 | 9 contacts → | ||||
Strong evidence “Bold Brain is a leading venture capital firm focused on the AI revolution in healthcare.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 6 | 8 contacts → | ||||
Partial evidence “Analytics Ventures (AV) is a venture studio fund dedicated to the inception of new ventures harnessing innovations in Artificial Intelligence.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 7 | 7 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 8 | 6 contacts → | ||||
Strong evidence “FusionX Ventures is an early-stage investment fund focused on helping companies build the next generation of cloud-enabled Smart Machines.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 9 | 6 contacts → | ||||
Partial evidence “Early-stage, highly supportive tech investment partnership” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 10 | 5 contacts → | ||||
Indirect evidence “We build creator-founded businesses.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 11 | 5 contacts → | ||||
Strong evidence “Teal Ventures, LP, is an early stage venture capital fund focused on disruptive innovation in health technology.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 12 | 4 contacts → | ||||
Partial evidence “MedTech Innovation Hub (MIH) is a venture studio that transforms promising healthcare technologies from concept to reality.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 13 | 4 contacts → | ||||
Strong evidence “We fuel early stage life science startups that focus on R&D tools, platform technologies, and computational biology to solve today's roadblocks and allow for tomorrow's…” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 14 | 3 contacts → | ||||
Strong evidence “Symphonic Capital is an early stage Venture Capital firm specializing in companies building AI enabled technology companies closing access gaps in health, wealth and climate.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 15 | 3 contacts → | ||||
Indirect evidence “Our Northstar portfolio prioritizes value-based disrupters allowing us to invest in start ups delivering reimagined business operating models.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 16 | 2 contacts → | ||||
Strong evidence “We are a Venture Capital Fund supporting ideas and startups in early stages.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 17 | 2 contacts → | ||||
Strong evidence “About Us At Syndicate 708, our investment thesis and accelerator focus is early stage deep tech.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 18 | 2 contacts → | ||||
Strong evidence “Keshif Ventures, LLC is a private Angel Investing company that invests in early stage companies primarily in the High Tech sector, and generally in the San Diego, CA area.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 19 | 1 contacts → | ||||
Strong evidence “Bridgewest Ventures (BV) is the Venture Capital arm of the Bridgewest Group.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 20 | 1 contacts → | ||||
Partial evidence “Longley Capital invests in meaningful companies at the forefront of emerging technologies.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 21 | 1 contacts → | ||||
Indirect evidence “Investing in early-stage entrepreneurs.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 22 | 1 contacts → | ||||
Strong evidence “Blackwing is a California-based, founder-first venture capital firm backing rule-breakers building America’s next era of industrial strength and technological leadership, from…” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
| 23 | 1 contacts → | ||||
Partial evidence “DePrima Ventures, was founded in 2001.” Source: RevenueBase Database · checked Sep 29, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: venture capital firms focused on deep tech companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names venture capital firms focused on deep tech companies.
- Partial evidence
- Its own public description names part of venture capital firms focused on deep tech companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name venture capital firms focused on deep tech companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 23 of 41 venture capital firms focused on deep tech companies based in San Diego, United States
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Venture capital firms focused on deep tech companies based in San Diego, United States at a glance
As of Sep 29, 2026Companies by employee count
Email recency for this list is measured across the whole United States list rather than for San Diego, so it is reported there. Company counts and contact totals on this page are exact for San Diego, over 41 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among venture capital firms focused on deep tech companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in San Diego, United States whose own description of what they do matches “venture capital firms focused on deep tech companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names venture capital firms focused on deep tech companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among venture capital firms focused on deep tech companies, and records with no verified work email. Companies headquartered outside San Diego are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 82 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 29, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Venture capital firms focused on deep tech companies by metro in the United States
- Venture capital firms focused on deep tech companies in San Francisco522
- Venture capital firms focused on deep tech companies in New York517
- Venture capital firms focused on deep tech companies in Palo Alto183
- Venture capital firms focused on deep tech companies in Boston131
- Venture capital firms focused on deep tech companies in Los Angeles123
- Venture capital firms focused on deep tech companies in Menlo Park107
- Venture capital firms focused on deep tech companies in Austin83
- Venture capital firms focused on deep tech companies in Chicago79
- Venture capital firms focused on deep tech companies in Miami64
- Venture capital firms focused on deep tech companies in Washington49
- Venture capital firms focused on deep tech companies in Dallas44
- Venture capital firms focused on deep tech companies in Atlanta41
- Venture capital firms focused on deep tech companies in Cambridge41
- Venture capital firms focused on deep tech companies in Houston41
- Venture capital firms focused on deep tech companies in Seattle40
- Venture capital firms focused on deep tech companies in Denver28
- Venture capital firms focused on deep tech companies in Santa Monica27
- Venture capital firms focused on deep tech companies in San Jose26
- Venture capital firms focused on deep tech companies in San Mateo26
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names venture capital firms focused on deep tech companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many venture capital firms focused on deep tech companies are there based in San Diego, United States?
RevenueBase identified 41 venture capital firms focused on deep tech companies headquartered in San Diego, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Harpoon, headquartered in San Diego, tops this list with the largest team on record.
Which city in the United States has the most venture capital firms focused on deep tech companies?
San Francisco leads the United States with 522 headquartered companies, followed by New York (517) and Palo Alto (183). San Diego has 41.
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 82 verified decision-maker contacts tracked across these 41 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 29, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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