Company lists · Data refreshed September 2026

Top 25 Systems biology software companies based in the United States

RevenueBase identified 230 company matches for systems biology software companies associated with the United States as of September 2026 and tracks 6,771 professional contacts across them, including 3,528 with verified work emails. San Francisco is the largest hub.

This list covers company matches for systems biology software companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 29, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 29, 2026 How this list was built
230Companies
6,771Contacts tracked
3,528Verified emails
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The 25 largest systems biology software companies based in the United States

Ranked by team size
Top 25 of 230 company matches for systems biology software companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 29, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchRadnor, PA, United StatesHQ recorded Sep 29, 20261,001-5,0001,237 contacts →

Exact match

“Certara accelerates medicines using proprietary biosimulation software, technology and services to transform traditional drug discovery and development.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
2Exact matchNew York, NY, United StatesHQ recorded Sep 29, 2026501-1,000957 contacts →

Exact match

“Schrödinger’s industry-leading computational platform facilitates the research efforts of biopharmaceutical and industrial companies, academic institutions, and government…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
3Exact matchBoston, MA, United StatesHQ recorded Sep 29, 2026501-1,000405 contacts →

Exact match

“Dotmatics is the global leader in R&D scientific software that connects science, data, and decision-making.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
4Exact matchBoulder, CO, United StatesHQ recorded Sep 29, 202651-200228 contacts →

Exact match

“Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
5Exact matchPleasanton, CA, United StatesHQ recorded Sep 29, 2026201-500219 contacts →

Exact match

“Here's the deal.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
6Exact matchDurham, NC, United StatesHQ recorded Sep 29, 2026201-500182 contacts →

Exact match

“Simulations Plus is a leading provider of modeling and simulation software and consulting services supporting drug discovery, development research, and regulatory submissions.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
7Exact matchNewark, CA, United StatesHQ recorded Sep 29, 202651-200124 contacts →

Exact match

“Bio-Techne Spatial, a leader in applied spatial biology solutions, empowers scientists and clinicians around the world to push the boundaries of science and medicine.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
8Exact matchNewark, CA, United StatesHQ recorded Sep 29, 202651-200122 contacts →

Exact match

“ATUM is an industry-leading provider of life science tools and solutions.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
9Exact matchSanta Fe, NM, United StatesHQ recorded Sep 29, 202651-200121 contacts →

Exact match

“OpenEye, Cadence Molecular Sciences is an industry leader in computational molecular design based on decades of delivering rapid, robust, and scalable software, toolkits, and…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
10Exact matchBoston, MA, United StatesHQ recorded Sep 29, 202651-200105 contacts →

Exact match

“Asimov builds tools to program living cells.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
11Exact matchBoston, MA, United StatesHQ recorded Sep 29, 202651-20093 contacts →

Exact match

“Metrum Research Group, established in 2004, is a global leader in biomedical modeling and simulation.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
12Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 29, 202651-20091 contacts →

Exact match

“We help scientists solve disease, develop drugs, and extend healthspan by building tools that simplify R&D, simulate biology, and untangle the complexity of life.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
13Exact matchPalo Alto, United StatesHQ recorded Sep 29, 2026201-50072 contacts →

Exact match

“BioMap is an AI for life sciences company, unmasking nature’s rules to generate proteins for a wide range of therapeutic and industrial applications.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
14Exact matchNorcross, GA, United StatesHQ recorded Sep 29, 202651-20063 contacts →

Exact match

“RayBiotech is a leading life sciences company providing proteomic discovery tools to scientists in 85 countries worldwide.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
15Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 29, 202651-20059 contacts →

Exact match

“We are leveraging artificial intelligence to map the glycoprotein control points that orchestrate disease progression-the missing link that genomics and proteomics can't see.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
16Exact matchWaltham, MA, United StatesHQ recorded Sep 29, 202611-5050 contacts →

Exact match

“Orionis Biosciences is a life sciences company pioneering technological innovation in genome-scale drug discovery and tunable molecular design of novel therapeutic drug modalities.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
17Exact matchMadison, WI, United StatesHQ recorded Sep 29, 202651-20050 contacts →

Exact match

“Genome International is a Bio-IT company that provides innovative software products and services in clinical genomics and Information Technology.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
18Exact matchLansdale, VA, United StatesHQ recorded Sep 29, 202611-5044 contacts →

Exact match

“VivproAI offers a revolutionary biointelligence software platform and innovative services to make evidence-based clinical, regulatory, and business decisions at lightning speed…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
19Exact matchCambridge, MA, United StatesHQ recorded Sep 29, 202651-20044 contacts →

Exact match

“Receptor.AI is a TechBio drug discovery company that combines a multi-platform AI ecosystem with a modality-agnostic decision engine to define the right therapeutic strategy and…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
20Exact matchNew York, NY, United StatesHQ recorded Sep 29, 202611-5043 contacts →

Exact match

“VantAI pairs bleeding-edge machine learning techniques with deep systems biology expertise to build computational models that uncover hidden relationships between molecules…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
21Exact matchSuite 203, United StatesHQ recorded Sep 29, 202651-20041 contacts →

Exact match

“Scilligence is a leading innovator of cross-platform, mobile cheminformatics and bioinformatics software solutions.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
22Exact matchSan Jose, CA, United StatesHQ recorded Sep 29, 202611-5036 contacts →

Exact match

“At BioNex Solutions, we develop instrumentation and integrated systems that solve the most demanding applications in biopharmaceutical, biotech, and academic research.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
23Exact matchBrooklyn, United StatesHQ recorded Sep 29, 202611-5035 contacts →

Exact match

“Overview: AccutarBio employs artificial intelligence to revolutionize drug discovery.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
24Exact matchSeattle, WA, United StatesHQ recorded Sep 29, 2026n/a34 contacts →

Exact match

“AI shouldn’t just summarize research.”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase
25Exact matchChicago, IL, United StatesHQ recorded Sep 29, 202611-5029 contacts →

Exact match

“SimBioSys is a pioneering TechBio company leveraging artificial intelligence and biophysical modeling to harness the power of spatial biophysics to redefine precision medicine…”

Recorded in the RevenueBase company graph · Sep 29, 2026 · View company records in RevenueBase

Showing 25 of 230 systems biology software companies based in the United States

See the full list, filter by size, metro and specialty, and access 3,528 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Systems biology software companies based in the United States at a glance

As of Sep 29, 2026
52.1%Verified-email coverage
29.4Average contacts per company
1-10Median size (employees)
6.5%Largest-city concentration · San Francisco
Sep 29, 2026Page data refreshed

Companies by employee count

1-10
133
11-50
65
51-200
21
201-500
7
501-1,000
2
1,001-5,000
1
5,001-10,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 230 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “systems biology software companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 3,528 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 29, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “systems biology software companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many systems biology software companies are there based in the United States?

RevenueBase identified 230 company matches for systems biology software companies associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Certara tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most systems biology software companies?

San Francisco leads with 15 company records, followed by Boston (14) and Cambridge (12).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 3,528 professional contacts with verified work emails tracked across these 230 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 29, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.