Company lists · Data refreshed September 2026

Top 25 Synthetic biology venture capital companies based in the United States

RevenueBase identified 280 synthetic biology venture capital companies headquartered in the United States as of September 2026 and tracks 6,915 professional contacts across them, including 3,987 with verified work emails and 3,211 with mobile numbers. San Francisco is the largest hub.

This list covers synthetic biology venture capital companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 6, 2026 86% judged on-target in blind review
280Companies
6,915Contacts tracked
3,987Verified emails
3,211Mobile numbers
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The 25 largest synthetic biology venture capital companies based in the United States

Ranked by team size
Top 25 of 280 synthetic biology venture capital companies based in the United States, ranked by team size, largest first. Data refreshed Sep 6, 2026. RevenueBase Smart Search rates how each company's information relates to synthetic biology venture capital companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 6, 2026501-1,0001,230 contacts →

“Twist Bioscience is a synthetic biology company based in South San Francisco, California.”

Source: company website · checked Sep 6, 2026
2Partial evidenceBoston, MA, United StatesHQ checked Sep 6, 2026501-1,000787 contacts →

“Ginkgo Bioworks builds the tools that make biology easier to engineer for everyone.”

Source: company website · checked Sep 6, 2026
3Indirect evidenceCambridge, MA, United StatesHQ checked Sep 6, 2026501-1,000753 contacts →

“Flagship Pioneering is a biotechnology company that invents and builds platform companies, each with the potential for multiple transformative human health and sustainability…”

Source: company website · checked Sep 6, 2026
4Partial evidenceSomerville, MA, United StatesHQ checked Sep 6, 2026201-500339 contacts →

“Pioneering generative biology to create breakthrough therapeutics.”

Source: company website · checked Sep 6, 2026
5Partial evidenceBoston, MA, United StatesHQ checked Sep 6, 2026201-500251 contacts →

“Founded in 2004, RA Capital Management is an active, multi-stage investment manager dedicated to evidence-based, science-led investing in public and private healthcare, life…”

Source: company website · checked Sep 6, 2026
6Strong evidenceCambridge, MA, United StatesHQ checked Sep 6, 202611-50123 contacts →

“Atlas Venture is a leading biotech venture capital firm.”

Source: company website · checked Sep 6, 2026
7Indirect evidenceNewark, CA, United StatesHQ checked Sep 6, 202651-200122 contacts →

“ATUM is an industry-leading provider of life science tools and solutions.”

Source: company website · checked Sep 6, 2026
8Indirect evidenceNew York, NY, United StatesHQ checked Sep 6, 202651-200116 contacts →

“RTW is a life sciences investment and innovation firm.”

Source: company website · checked Sep 6, 2026
9Indirect evidenceBoston, MA, United StatesHQ checked Sep 6, 202651-200113 contacts →

“We discover, launch and build great companies based on bold ideas that meet at the intersection of science, strategy, business and medicine – where transformational science meets…”

Source: company website · checked Sep 6, 2026
10Indirect evidenceBoston, MA, United StatesHQ checked Sep 6, 202651-200105 contacts →

“Asimov builds tools to program living cells.”

Source: company website · checked Sep 6, 2026
11Indirect evidenceBoston, MA, United StatesHQ checked Sep 6, 202611-5095 contacts →

“MPM BioImpact is a world-leading biotechnology investment firm with nearly three decades of experience creating and investing in companies that seek to translate scientific…”

Source: company website · checked Sep 6, 2026
12Strong evidenceSan Carlos, CA, United StatesHQ checked Sep 6, 202651-20087 contacts →

“We are now at the dawn of the synthetic biology revolution, which will spawn new applications, markets, and business models, improving human lives in countless ways.”

Source: company website · checked Sep 6, 2026
13Strong evidenceNew York, NY, United StatesHQ checked Sep 6, 202611-5082 contacts →

“Lux Capital is a venture capital firm investing in emerging science and technology at the outermost edges of what is possible.”

Source: company website · checked Sep 6, 2026
14Strong evidenceSeattle, WA, United StatesHQ checked Sep 6, 202651-20079 contacts →

“Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…”

Source: company website · checked Sep 6, 2026
15Indirect evidenceSouth San Francisco, CA, United StatesHQ checked Sep 6, 202651-20073 contacts →

“Our mission is to create a new generation of smarter medicines that outmaneuver complex diseases in ways previously inconceivable.”

Source: company website · checked Sep 6, 2026
16Indirect evidenceLebanon, NH, United StatesHQ checked Sep 6, 202651-20063 contacts →

“Mascoma, as one of Lallemand’s research and development centers, creates new industrial biotechnology products for the global marketplace that enable the efficient and sustainable…”

Source: company website · checked Sep 6, 2026
17Strong evidenceSan Diego, CA, United StatesHQ checked Sep 6, 202651-20061 contacts →

“Telesis Bio is empowering researchers to accelerate the creation of novel synthetic biology solutions to address some of humanity’s greatest challenges.”

Source: company website · checked Sep 6, 2026
18Indirect evidenceDurham, NC, United StatesHQ checked Sep 6, 202611-5054 contacts →

“DMC is a U.S.”

Source: company website · checked Sep 6, 2026
19Indirect evidenceOakland, CA, United StatesHQ checked Sep 6, 202651-20050 contacts →

“Aditum Bio, from the Latin word for “access”, was founded on a simple mission: to give patients access to medicines that may not otherwise be developed.”

Source: company website · checked Sep 6, 2026
20Strong evidenceCambridge, MA, United StatesHQ checked Sep 6, 202611-5047 contacts →

“GC Therapeutics Inc.(GCTx) uses synthetic biology to program patient-derived stem cells into any cell type with best-in-class efficiency (up to 10X), speed (up to 100X) and…”

Source: company website · checked Sep 6, 2026
21Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 6, 2026n/a45 contacts →

“IndieBio is now known as SOSV NY and SOSV SF.”

Source: company website · checked Sep 6, 2026
22Partial evidenceBoston, MA, United StatesHQ checked Sep 6, 202611-5044 contacts →

“Superluminal Medicines is a Boston-based generative biology and chemistry company developing a differentiated pipeline and revolutionizing the speed and accuracy of how medicine…”

Source: company website · checked Sep 6, 2026
23Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 6, 202611-5043 contacts →

“5AM was founded in 2002 and pursues investments in advanced life science innovations, and seeks to be diversified across the biopharmaceutical therapeutics, and platform…”

Source: company website · checked Sep 6, 2026
24Indirect evidenceBoston, CA, United StatesHQ checked Sep 6, 202651-20042 contacts →

“Inscripta merged with Manus in April 2025 to establish a unique end-to-end platform for scalable development, biomanufacturing, and commercialization of bioalternative products.”

Source: company website · checked Sep 6, 2026
25Indirect evidenceBoston, MA, United StatesHQ checked Sep 6, 202611-5040 contacts →

“Pillar VC is with you from the beginning.”

Source: company website · checked Sep 6, 2026

Showing 25 of 280 synthetic biology venture capital companies based in the United States

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Synthetic biology venture capital companies based in the United States at a glance

As of Sep 6, 2026
57.7%Verified-email coverage
46.4%Mobile-number coverage
24.7Average contacts per company
1-10Median size (employees)
10.4%Largest-city concentration · San Francisco
Sep 6, 2026Page data refreshed

Companies by employee count

1-10
163
11-50
87
51-200
22
201-500
3
501-1,000
4

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among synthetic biology venture capital companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “synthetic biology venture capital companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names synthetic biology venture capital companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among synthetic biology venture capital companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 3,987 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 6, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Synthetic biology venture capital companies by metro

  • Synthetic biology venture capital companies in San Francisco29

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names synthetic biology venture capital companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many synthetic biology venture capital companies are there based in the United States?

RevenueBase identified 280 synthetic biology venture capital companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Twist Bioscience, headquartered in South San Francisco, tops this list with the largest team on record.

Which city has the most synthetic biology venture capital companies?

San Francisco leads with 29 headquartered companies, followed by Boston (23) and New York (19).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 3,987 verified decision-maker contacts tracked across these 280 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.