Company lists · Data refreshed September 2026

Top 19 Specialty healthcare software companies based in South Africa

RevenueBase identified 49 specialty healthcare software companies headquartered in South Africa as of September 2026 and tracks 1,053 professional contacts across them, including 294 with verified work emails and 42 with mobile numbers. Johannesburg is the largest hub.

This list covers specialty healthcare software companies headquartered in South Africa, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 6, 2026 86% judged on-target in blind review
49Companies
1,053Contacts tracked
294Verified emails
42Mobile numbers
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The 19 largest specialty healthcare software companies based in South Africa

Ranked by team size
Top 19 of 49 specialty healthcare software companies based in South Africa, ranked by team size, largest first. Data refreshed Sep 6, 2026. RevenueBase Smart Search rates how each company's information relates to specialty healthcare software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceJohannesburg, South AfricaHQ checked Sep 6, 202651-200252 contacts →

“Our comprehensive suite of solutions includes medical billing and clinical software, bureau services, and value-added services that free up valuable time for practitioners to…”

Source: company website · checked Sep 6, 2026
2Indirect evidenceJohannesburg, South AfricaHQ checked Sep 6, 202651-20079 contacts →

“First Care Solutions is a medical administration and services company founded in 2007.”

Source: company website · checked Sep 6, 2026
3Indirect evidenceCentury City, South AfricaHQ checked Sep 6, 202651-20051 contacts →

“CGM recognises the extra in the ordinary; the little things that transform the ordinary into something remarkable.”

Source: company website · checked Sep 6, 2026
4Partial evidenceCenturion, South AfricaHQ checked Sep 6, 202651-20037 contacts →

“At SpesNet, we're at the forefront of healthcare solutions for providers, insurers, administrators, and managed care organisations.”

Source: company website · checked Sep 6, 2026
5Partial evidencePretoria, South AfricaHQ checked Sep 6, 202651-20033 contacts →

“At Allegra, we believe in the power of technology to improve efficiencies for healthcare providers.”

Source: company website · checked Sep 6, 2026
6Strong evidencePretoria, South AfricaHQ checked Sep 6, 202651-20025 contacts →

“TriFour provides specialist Information Technology (IT) solutions and services to the healthcare market that improves patient outcomes and enhances cash flows.”

Source: company website · checked Sep 6, 2026
7Indirect evidenceCape Town, South AfricaHQ checked Sep 6, 202611-5019 contacts →

“PBT Insurance Technologies was established in 1998 with its prime focus on the health administration sector.”

Source: company website · checked Sep 6, 2026
8Indirect evidenceGreenstone, South AfricaHQ checked Sep 6, 202611-5013 contacts →

“Revolutionising Radiology: At Continuum Systems, we are dedicated to transforming the radiology journey for patients and stakeholders alike.”

Source: company website · checked Sep 6, 2026
9Partial evidencePretoria, South AfricaHQ checked Sep 6, 202611-5012 contacts →

“Vertice Mobile Healthcare is a leading provider of comprehensive healthcare solutions, serving both public and private sectors with a focus on radiology, mobile and alternative…”

Source: company website · checked Sep 6, 2026
10Partial evidenceMargate, South AfricaHQ checked Sep 6, 202651-20010 contacts →

“The founders of Medical EDI Services have been developing medical billing and practice management software for the medical fraternity for the past twenty years.”

Source: company website · checked Sep 6, 2026
11Strong evidenceHout Bay, South AfricaHQ checked Sep 6, 20261-107 contacts →

“Boost Your Medical Practice Efficiency and Online Visibility with Bookem’s All-in-One Integrated Healthcare Solution Bookem’s practice management and EHR software streamlines…”

Source: company website · checked Sep 6, 2026
12Indirect evidenceCenturion, South AfricaHQ checked Sep 6, 202651-2007 contacts →

“Brand Our philosophy is to provide systems and service which exceed the requirements of our clients and their customers, enabling them to operate efficiently and successfully.”

Source: company website · checked Sep 6, 2026
13Strong evidencePretoria, South AfricaHQ checked Sep 6, 202611-507 contacts →

Healthcare Framework HCF is a cloud-based healthcare software application which is used to capture clinical data, manage patient workflow, electronic medical records (EMR) and…”

Source: company website · checked Sep 6, 2026
14Partial evidenceCape Town, South AfricaHQ checked Sep 6, 20261-106 contacts →

“HealthWare Medical Technology provides a complete software solution to manage the clinical, administrative and financial requirements of any care home facility or hospital.”

Source: company website · checked Sep 6, 2026
15Partial evidenceFourways, South AfricaHQ checked Sep 6, 20261-105 contacts →

“KITRIN is a company focused on assisting business owners, including healthcare practitioners in private practice, with their operational business functions so that they can…”

Source: company website · checked Sep 6, 2026
16Strong evidenceCape Town, South AfricaHQ checked Sep 6, 20261-105 contacts →

“We redefine healthcare interactions with specialized Practice Management solutions, including patient onboarding, billing, and integrated payments.”

Source: company website · checked Sep 6, 2026
17Strong evidencePretoria, South AfricaHQ checked Sep 6, 202611-504 contacts →

“Our primary focus is to develop, deploy and support software in the healthcare industry.”

Source: company website · checked Sep 6, 2026
18Partial evidenceJohannesburg, South AfricaHQ checked Sep 6, 202611-503 contacts →

“IKAT G3 Advanced PMA Software is dedicated to helping medical practitioners transform their administration into an efficient and profitable business process.”

Source: company website · checked Sep 6, 2026
19Indirect evidenceJohannesburg, South AfricaHQ checked Sep 6, 202611-502 contacts →

“Welcome to ZTI Health & Technology - Your Partner in Process Engineering and Health Tech Solutions ZTI Health & Technology is your premier destination for innovative Process…”

Source: company website · checked Sep 6, 2026

Showing 19 of 49 specialty healthcare software companies based in South Africa

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Specialty healthcare software companies based in South Africa at a glance

As of Sep 6, 2026
27.9%Verified-email coverage
4.0%Mobile-number coverage
21.5Average contacts per company
11-50Median size (employees)
26.5%Largest-city concentration · Johannesburg
Sep 6, 2026Page data refreshed

Companies by employee count

1-10
19
11-50
15
51-200
13
201-500
2

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among specialty healthcare software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in South Africa whose own description of what they do matches “specialty healthcare software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names specialty healthcare software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among specialty healthcare software companies, and records with no verified work email. Companies headquartered outside South Africa are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 294 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 6, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names specialty healthcare software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many specialty healthcare software companies are there based in South Africa?

RevenueBase identified 49 specialty healthcare software companies headquartered in South Africa as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Healthbridge, headquartered in Johannesburg, tops this list with the largest team on record.

Which city has the most specialty healthcare software companies?

Johannesburg leads with 13 headquartered companies, followed by Cape Town (8) and Pretoria (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 294 verified decision-maker contacts tracked across these 49 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 6, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.