Company lists · Data refreshed November 2026

Top 25 Small molecule drug developers based in the United States

RevenueBase identified 489 company matches for small molecule drug developers associated with the United States as of November 2026 and tracks 15,362 professional contacts across them, including 6,598 with verified work emails. San Diego is the largest hub.

This list covers company matches for small molecule drug developers associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed November 6, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Nov 6, 2026 How this list was built
489Companies
15,362Contacts tracked
6,598Verified emails
Explore this list → Free signup · no credit card · 500 free credits

The 25 largest small molecule drug developers based in the United States

Ranked by team size
Top 25 of 489 company matches for small molecule drug developers based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Nov 6, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchHayward, CA, United StatesHQ recorded Nov 6, 2026501-1,000647 contacts →

Exact match

“Arcus Biosciences is a rapidly growing, clinical-stage, global biopharmaceutical company developing differentiated molecules and combination medicines that may have the potential…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
2Exact matchDevens, MA, United StatesHQ recorded Nov 6, 2026501-1,000605 contacts →

Exact match

“Veranova is a global leader in process development and manufacturing of active pharmaceutical ingredients (APIs), with a focus on specialty and complex chemistry for small…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
3Exact matchSouthborough, MA, United StatesHQ recorded Nov 6, 2026501-1,000506 contacts →

Exact match

“Veristat is the science-first full-service drug and biologic CRO and consultancy that integrates strategic planning, regulatory expertise, and clinical trial execution to rapidly…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
4Exact matchPrinceton, NJ, United StatesHQ recorded Nov 6, 2026201-500413 contacts →

Exact match

“The mission of Taiho Oncology, Inc.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
5Exact matchMiami, NJ, United StatesHQ recorded Nov 6, 2026201-500356 contacts →

Exact match

“Summit Mission Statement: To build a viable, long-lasting health care organization that assumes full responsibility for designing, developing, trial execution and enrollment…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
6Exact matchPasadena, CA, United StatesHQ recorded Nov 6, 2026501-1,000352 contacts →

Exact match

“Arrowhead Pharmaceuticals is a clinical stage, Nasdaq listed (ticker ARWR) company developing medicines that treat intractable diseases by silencing the genes that cause them.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
7Exact matchSan Diego, CA, United StatesHQ recorded Nov 6, 20261,001-5,000304 contacts →

Exact match

“Crown Bioscience, a JSR Life Sciences company, is a global contract research organization (CRO) providing discovery, preclinical, and translational platforms to advance oncology…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
8Exact matchCambridge, MA, United StatesHQ recorded Nov 6, 202651-200298 contacts →

Exact match

“Nuvalent is creating precisely targeted therapies for patients with cancer designed to overcome the limitations of existing therapies for clinically proven kinase targets.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
9Exact matchSan Diego, CA, United StatesHQ recorded Nov 6, 2026201-500286 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
10Exact matchBend, OR, United StatesHQ recorded Nov 6, 2026201-500186 contacts →

Exact match

“At Serán, Our mission is to provide optimized drug development and manufacturing services for our clients, from discovery to the clinic.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
11Exact matchWatertown, MA, United StatesHQ recorded Nov 6, 202651-200176 contacts →

Exact match

“Treeline (or Treeline Biosciences) is a privately held, clinical-stage biopharma company that aspires to make medicines at the highest level.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
12Exact matchPasadena, CA, United StatesHQ recorded Nov 6, 202651-200144 contacts →

Exact match

“Terray is a biotechnology company with the technology, data, and mindset to radically change the way we discover and develop small molecule therapeutics.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
13Exact matchPrinceton, NJ, United StatesHQ recorded Nov 6, 202651-200143 contacts →

Exact match

“NJ Bio Inc.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
14Exact matchNewark, CA, United StatesHQ recorded Nov 6, 202651-200141 contacts →

Exact match

“Protagonist Therapeutics (Nasdaq: PTGX) is a biopharmaceutical company with a proprietary technology platform focused on discovering and developing peptide-based new chemical…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
15Exact matchMalvern, PA, United StatesHQ recorded Nov 6, 202651-200130 contacts →

Exact match

“Reaction Biology specializes in answering your complex scientific questions to accelerate the development of your breakthrough therapeutic candidates.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
16Exact matchCampbell, CA, United StatesHQ recorded Nov 6, 202611-50123 contacts →

Exact match

“With demonstrated clinical development and commercialization expertise, VIVUS is dedicated to addressing the therapeutic needs of patients with serious medical conditions and…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
17Exact matchCambridge, MA, United StatesHQ recorded Nov 6, 202651-200118 contacts →

Exact match

“Pioneering Medicines, Flagship Pioneering’s in house drug discovery and development unit, is dedicated to conceiving and developing a broad portfolio of life-changing treatments…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
18Exact matchSouth San Francisco, CA, United StatesHQ recorded Nov 6, 202611-50118 contacts →

Exact match

“NGM Bio is a biopharmaceutical company focused on discovering and developing novel, life-changing medicines for people whose health and lives have been disrupted by disease.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
19Exact matchBoston, MA, United StatesHQ recorded Nov 6, 202651-200110 contacts →

Exact match

“Nimbus Therapeutics is a clinical-stage, structure-based drug discovery company developing novel small molecule medicines designed to act against well-validated but…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
20Exact matchCypress, United StatesHQ recorded Nov 6, 2026201-500107 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
21Exact matchJupiter, FL, United StatesHQ recorded Nov 6, 202611-50106 contacts →

Exact match

“Ligand is a leading royalty aggregator, partnering with biopharmaceutical companies to finance and advance late-stage clinical development programs.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
22Exact matchBoston, MA, United StatesHQ recorded Nov 6, 202651-20092 contacts →

Exact match

“Jnana Therapeutics is a clinical-stage biotechnology company leveraging its next-generation chemoproteomics RAPID platform to discover medicines for highly validated…”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
23Exact matchWaltham, MA, United StatesHQ recorded Nov 6, 202611-5086 contacts →

Exact match

“At Ventus, we are pioneering a unique approach to structure-based drug discovery to address biologically validated, but difficult-to-drug targets.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
24Exact matchNewtown, PA, United StatesHQ recorded Nov 6, 202651-20082 contacts →

Exact match

“Founded in 2014, SynSmart has made its name in chemistry services for early-stage discovery projects as well as collaborative scale-up and manufacturing support services.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase
25Exact matchSouth San Francisco, CA, United StatesHQ recorded Nov 6, 202611-5078 contacts →

Exact match

“Circle Pharma initiated operations in June 2014 with seed funding from Pfizer, Inc.”

Recorded in the RevenueBase company graph · Nov 6, 2026 · View company records in RevenueBase

Showing 25 of 489 small molecule drug developers based in the United States

See the full list, filter by size, metro and specialty, and access 6,598 tracked professional contacts with verified work emails. Direct dials are available where recorded.

Free signup · no credit card

View the full list →

Small molecule drug developers based in the United States at a glance

As of Nov 6, 2026
43.0%Verified-email coverage
31.4Average contacts per company
11-50Median size (employees)
8.4%Largest-city concentration · San Diego
Nov 6, 2026Page data refreshed

Companies by employee count

1-10
243
11-50
160
51-200
53
201-500
15
501-1,000
12
1,001-5,000
6

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 489 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “small molecule drug developers” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 6,598 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on November 6, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Small molecule drug developers by metro

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “small molecule drug developers”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many small molecule drug developers are there based in the United States?

RevenueBase identified 489 company matches for small molecule drug developers associated with the United States as of November 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Arcus Biosciences tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most small molecule drug developers?

San Diego leads with 41 company records, followed by Cambridge (23) and New York (22).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 6,598 professional contacts with verified work emails tracked across these 489 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on November 6, 2026.

Ready to reach these companies? Verified emails and direct dials for all 489 small molecule drug developers based in the United States. Start with a free account, no credit card.

Download this list →

Related lists

About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.