Company lists · Data refreshed September 2026
Top 25 Research software companies based in the United States
RevenueBase identified 115 research software companies headquartered in the United States as of September 2026 and tracks 3,701 professional contacts across them, including 1,457 with verified work emails and 1,240 with mobile numbers. San Diego is the largest hub.
This list covers research software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest research software companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | JMPPartial evidence | 557 | |||
“Great software in the right hands can change the world.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 2 | WolframStrong evidence | 551 | |||
“Founded by Stephen Wolfram in 1987, Wolfram Research is one of the world's most respected computer, web, and cloud software companies-as well as a powerhouse of scientific and…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 3 | 450 | ||||
“SaaS Products & Services for R&D that drive discovery, accelerate studies, and advance your research.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 4 | 405 | ||||
“Dotmatics is the global leader in R&D scientific software that connects science, data, and decision-making.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 5 | IntellisurveyStrong evidence | 142 | |||
“IntelliSurvey provides software and services to help professional researchers make business decisions.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 6 | 106 | ||||
“Biosero develops science-centric software and laboratory automation solutions that help researchers orchestrate discovery.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 7 | 91 | ||||
“We help scientists solve disease, develop drugs, and extend healthspan by building tools that simplify R&D, simulate biology, and untangle the complexity of life.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 8 | 84 | ||||
“Founded in 2002, ROI Rocket provides full-service research, marketing and sales automation, and digital agency support to consultants, investors, corporate clients, and the…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 9 | 67 | ||||
“Research Metrics was founded in 2004 to develop mystery shopping software.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 10 | 59 | ||||
“Protein Metrics' vendor-neutral software allows scientists to use data generated on analytical instruments like mass spectrometers to quickly identify and report protein sequences…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 11 | Minerva Research SolutionsPartial evidence | 49 | |||
“A Research Solutions Company.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 12 | 46 | ||||
Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 13 | Ilab Operations Software, A Part Of Agilent TechnologiesPartial evidence | 41 | |||
“iLab Solutions, now a part of Agilent Technologies, provides scientific organizations with unique research management and product selection tools.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 14 | Mercury AnalyticsPartial evidence | 39 | |||
“At Mercury’s core, we are research experts who pride ourselves on creating advanced and innovative technologies for executing online research.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 15 | 33 | ||||
“Idea Elan specializes in applications and products that enhance lab productivity and management.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 16 | 32 | ||||
“We’re a team of highly experienced scientists, engineers, and entrepreneurs dedicated to accelerating your science.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 17 | 26 | ||||
“DNASTAR is a global software company that has been meeting the needs of life scientists for over 40 years by providing innovative and easy-to-use desktop software tools for…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 18 | 25 | ||||
“MetaCell is a life science-focused software company composed of scientists and software engineers with deep domain expertise in computational neuroscience, molecular biology, data…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 19 | 25 | ||||
“BioInformatics helps companies in the life science space navigate the dynamic life science industry with confidence.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 20 | 25 | ||||
“We’re building the operating system for biology.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 21 | 20 | ||||
“DeltaSoft has been providing scientific software and expert services for research companies since 1996.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 22 | Phoenix BioinformaticsPartial evidence | 20 | |||
“Phoenix Bioinformatics is the nonprofit home of trusted, community-led research tools, resources, & database solutions, including MorphoBank & TAIR.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 23 | FluorofinderPartial evidence | 18 | |||
“FluoroFinder is developing innovative cloud-based research tools for the search of fluorescent reagents and the design of medical experiments: accelerating the research…” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 24 | 17 | ||||
“We build and manage the software and data systems that keep modern laboratories running, connecting instruments, workflows, and analytics into one reliable flow of information.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
| 25 | 16 | ||||
“BioDiscovery, Inc.” Source: company website · checked Sep 5, 2026Thanks. The Data Team will review it. | |||||
Showing 25 of 115 research software companies based in the United States
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Research software companies based in the United States at a glance
As of Sep 5, 2026Companies by employee count
Verified emails by last verification
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among research software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “research software companies”. Matching reads each company's description, not its industry code or its name.
- What we exclude
- Companies whose own description does not clearly place them among research software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 1,457 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
How many research software companies are there based in the United States?
RevenueBase identified 115 research software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
JMP, headquartered in Cary, tops this list with the largest team on record.
Which city has the most research software companies?
San Diego leads with 9 headquartered companies, followed by Boston (6) and Madison (5).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,457 verified decision-maker contacts tracked across these 115 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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