Company lists · Data refreshed September 2026

Top 25 Rare pulmonary disease companies based in the United States

RevenueBase identified 141 rare pulmonary disease companies headquartered in the United States as of September 2026 and tracks 3,280 professional contacts across them, including 1,677 with verified work emails. San Diego is the largest hub.

This list covers rare pulmonary disease companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 21, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 21, 2026 86% judged on-target in blind review
141Companies
3,280Contacts tracked
1,677Verified emails
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The 25 largest rare pulmonary disease companies based in the United States

Ranked by team size
Top 25 of 141 rare pulmonary disease companies based in the United States, ranked by team size, largest first. Data refreshed Sep 21, 2026. RevenueBase Smart Search rates how each company's information relates to rare pulmonary disease companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceDanbury, CT, United StatesHQ checked Sep 21, 2026501-1,000732 contacts →

Partial evidence

“MannKind Corporation (Nasdaq: MNKD) is a biopharmaceutical company dedicated to transforming chronic disease care through innovative, patient-centric solutions.”

Source: RevenueBase Database · checked Sep 21, 2026
2Indirect evidenceRedwood City, CA, United StatesHQ checked Sep 21, 2026201-500280 contacts →

Indirect evidence

“Pulmonx has developed the Zephyr Endobronchial Valve, a minimally invasive treatment for COPD/emphysema.”

Source: RevenueBase Database · checked Sep 21, 2026
3Partial evidenceMorrisville, NC, United StatesHQ checked Sep 21, 202651-200221 contacts →

Partial evidence

“Liquidia Corporation is a biopharmaceutical company focused on the development and commercialization of products in pulmonary hypertension and other applications of its PRINT®…”

Source: RevenueBase Database · checked Sep 21, 2026
4Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 21, 202651-200165 contacts →

Partial evidence

“Theravance Biopharma aims to transform the treatment of specialty respiratory and neurologic diseases by delivering Medicines that Make a Difference® in patients’ and caregivers’…”

Source: RevenueBase Database · checked Sep 21, 2026
5Partial evidenceSan Diego, CA, United StatesHQ checked Sep 21, 202651-200164 contacts →

Partial evidence

“Gossamer Bio is a clinical-stage biopharmaceutical company focused on the development and commercialization of seralutinib for the treatment of pulmonary arterial hypertension…”

Source: RevenueBase Database · checked Sep 21, 2026
6Indirect evidenceWeston, FL, United StatesHQ checked Sep 21, 202651-20097 contacts →

Indirect evidence

“Transpire Bio Inc.”

Source: RevenueBase Database · checked Sep 21, 2026
7Strong evidenceUnited StatesHQ checked Sep 21, 202651-20090 contacts →

Strong evidence

“Savara is a clinical stage biopharmaceutical company focused on rare respiratory diseases.”

Source: RevenueBase Database · checked Sep 21, 2026
8Indirect evidenceEagan, MN, United StatesHQ checked Sep 21, 202651-20071 contacts →

Indirect evidence

“We’re a company built on the belief that we can improve the standard of care for people with compromised respiratory systems.”

Source: RevenueBase Database · checked Sep 21, 2026
9Indirect evidenceMiami, FL, United StatesHQ checked Sep 21, 202611-5070 contacts →

Indirect evidence

“The COPD Foundation is a nonprofit organization established to help millions of people live longer and healthier lives by advancing research, advocacy, and awareness to stop…”

Source: RevenueBase Database · checked Sep 21, 2026
10Indirect evidenceGarden City, NY, United StatesHQ checked Sep 21, 202651-20069 contacts →

Indirect evidence

“AIT Therapeutics, commencing June 26, 2019 is named Beyond Air®.”

Source: RevenueBase Database · checked Sep 21, 2026
11Indirect evidenceNovato, CA, United StatesHQ checked Sep 21, 20261,001-5,00067 contacts →

Indirect evidence

“Leading with purpose.”

Source: RevenueBase Database · checked Sep 21, 2026
12Partial evidenceAndover, MA, United StatesHQ checked Sep 21, 202651-20066 contacts →

Partial evidence

“For 30 years, ndd has been dedicated to transforming how the world detects, understands, and manages lung disease.”

Source: RevenueBase Database · checked Sep 21, 2026
13Indirect evidenceSan Jose, CA, United StatesHQ checked Sep 21, 202651-20059 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 21, 2026
14Strong evidenceJersey City, NJ, United StatesHQ checked Sep 21, 202611-5059 contacts →

Strong evidence

“At SCYNEXIS, we are committed to improving outcomes for patients living with severe, progressive, and underserved rare diseases.”

Source: RevenueBase Database · checked Sep 21, 2026
15Partial evidenceGoleta, CA, United StatesHQ checked Sep 21, 202611-5056 contacts →

Partial evidence

“Vascular BioSciences (VBS), a biomedical company with operations in Research Triangle, NC, San Diego, and Goleta, CA, makes interventional catheters to obtain pulmonary…”

Source: RevenueBase Database · checked Sep 21, 2026
16Strong evidenceDeer Park, IL, United StatesHQ checked Sep 21, 202651-20053 contacts →

Strong evidence

“Eton Pharmaceuticals is an innovative pharmaceutical company focused on developing and commercializing treatments for rare diseases.”

Source: RevenueBase Database · checked Sep 21, 2026
17Partial evidenceBoston, MA, United StatesHQ checked Sep 21, 202611-5051 contacts →

Partial evidence

“Avalyn is reimagining the future of pulmonary fibrosis treatment, with a pipeline of new inhaled formulations of approved medicines.”

Source: RevenueBase Database · checked Sep 21, 2026
18Strong evidenceWaltham, MA, United StatesHQ checked Sep 21, 202611-5047 contacts →

Strong evidence

“Pulmovant is a clinical-stage biotechnology company committed to transforming the lives of patients with pulmonary diseases and is a Roivant (Nasdaq: ROIV) company.”

Source: RevenueBase Database · checked Sep 21, 2026
19Indirect evidenceSan Diego, United StatesHQ checked Sep 21, 202611-5043 contacts →

Indirect evidence

“Endeavor BioMedicines is a clinical-stage biotechnology company developing medicines with the potential to deliver transformational clinical benefits to patients with…”

Source: RevenueBase Database · checked Sep 21, 2026
20Partial evidenceDurham, NC, United StatesHQ checked Sep 21, 202611-5029 contacts →

Partial evidence

“Polarean is a revenue-generating medical imaging technology company revolutionizing pulmonary medicine through direct visualization of lung function by introducing the power and…”

Source: RevenueBase Database · checked Sep 21, 2026
21Strong evidenceWilmington, DE, United StatesHQ checked Sep 21, 202611-5026 contacts →

Strong evidence

“We are a clinical-stage pharmaceutical company developing therapeutics to modify the course of cardiopulmonary diseases, namely, Pulmonary Arterial Hypertension (“PAH”), in which…”

Source: RevenueBase Database · checked Sep 21, 2026
22Partial evidenceOrange City, FL, United StatesHQ checked Sep 21, 202611-5021 contacts →

Partial evidence

Pulmonary Practice Associates, practice of P.T.”

Source: RevenueBase Database · checked Sep 21, 2026
23Indirect evidenceMaple Grove, MN, United StatesHQ checked Sep 21, 202651-20021 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 21, 2026
24Indirect evidenceChapel Hill, United StatesHQ checked Sep 21, 202611-5021 contacts →

Indirect evidence

“Tenax Therapeutics is a Phase 3, development-stage pharmaceutical company using clinical insights to develop novel cardiopulmonary therapies.”

Source: RevenueBase Database · checked Sep 21, 2026
25Indirect evidenceSan Mateo, CA, United StatesHQ checked Sep 21, 202611-5020 contacts →

Indirect evidence

“Aerogen Pharma is a US based clinical-stage specialty pharmaceutical company with a mission to develop inhaled drug/biologic and device combination that will transform the…”

Source: RevenueBase Database · checked Sep 21, 2026

Showing 25 of 141 rare pulmonary disease companies based in the United States

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Rare pulmonary disease companies based in the United States at a glance

As of Sep 21, 2026
51.1%Verified-email coverage
23.3Average contacts per company
11-50Median size (employees)
5.7%Largest-city concentration · San Diego
Sep 21, 2026Page data refreshed

Companies by employee count

1-10
66
11-50
53
51-200
19
201-500
1
501-1,000
1
1,001-5,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 141 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among rare pulmonary disease companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “rare pulmonary disease companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names rare pulmonary disease companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among rare pulmonary disease companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,677 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 21, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names rare pulmonary disease companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many rare pulmonary disease companies are there based in the United States?

RevenueBase identified 141 rare pulmonary disease companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Mannkind Corporation, headquartered in Danbury, tops this list with the largest team on record.

Which city has the most rare pulmonary disease companies?

San Diego leads with 8 headquartered companies, followed by Boston (6) and Houston (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,677 verified decision-maker contacts tracked across these 141 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 21, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.