Company lists · Data refreshed September 2026

Top 25 Quality management software companies based in the United States

RevenueBase identified 172 quality management software companies headquartered in the United States as of September 2026 and tracks 4,199 professional contacts across them, including 1,219 with verified work emails and 1,110 with mobile numbers. Houston is the largest hub.

This list covers quality management software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
172Companies
4,199Contacts tracked
1,219Verified emails
1,110Mobile numbers
Explore all 172 companies → Free signup · no credit card · 500 free credits

The 25 largest quality management software companies based in the United States

Ranked by team size
Top 25 of 172 quality management software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names quality management software companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#CompanyHeadquartersEmployeesContacts
1
Caliber TechnologiesStrong evidence
Pittsburgh, PA, United StatesHQ checked Sep 5, 2026501-1,000860

“For over 25 years, Caliber has helped regulated industries modernize quality, laboratory, and manufacturing operations through software built for regulatory compliance.”

Source: company website · checked Sep 5, 2026
2
ILABStrong evidence
Indianapolis, IN, United StatesHQ checked Sep 5, 2026501-1,000417

“iLAB specializes in Software Quality Assurance services, providing global solutions to our customers.”

Source: company website · checked Sep 5, 2026
3
ETQStrong evidence
Burlington, MA, United StatesHQ checked Sep 5, 2026201-500254

“Octave Reliance (formerly ETQ Reliance) is the leading Quality, EHS, Food Safety and Compliance management software for identifying, mitigating and preventing high-risk events…”

Source: company website · checked Sep 5, 2026
4
DOT CompliancePartial evidence
Phoenix, AZ, United StatesHQ checked Sep 5, 2026201-500202

“Dot Compliance offers an AI-powered, Salesforce-native eQMS featuring the industry’s first AI specifically built to deliver safe, reliable decision guidance for critical quality…”

Source: company website · checked Sep 5, 2026
5
Greenlight GuruIndirect evidence
Indianapolis, IN, United StatesHQ checked Sep 5, 2026201-500139

“Greenlight Guru is the #1 provider of modern cloud-based QMS & EDC solutions for the MedTech industry, helping companies bring life-changing products to market faster, more…”

Source: company website · checked Sep 5, 2026
6
QualioStrong evidence
San Francisco, CA, United StatesHQ checked Sep 5, 202651-200119

Qualio is a unified quality and compliance management platform that helps regulated organizations get products to market faster with reduced risk.”

Source: company website · checked Sep 5, 2026
7North Olmsted, OH, United StatesHQ checked Sep 5, 2026201-500100

“Building on 30+ years of experience, IQS is modern, enterprise-grade quality management software designed to help our customers ensure compliance and bring the highest quality…”

Source: company website · checked Sep 5, 2026
8
ZenqmsStrong evidence
Ardmore, PA, United StatesHQ checked Sep 5, 202651-20098

“ZenQMS is on a mission to elevate the role of Quality in the Life Sciences and support Quality professionals with easy-to-use digital process management.”

Source: company website · checked Sep 5, 2026
9
Cmx1 CompliancemetrixIndirect evidence
San Diego, CA, United StatesHQ checked Sep 5, 202651-20078

“We power everyday excellence at the world's most trusted brands.”

Source: company website · checked Sep 5, 2026
10
SEMBIStrong evidence
Austin, TX, United StatesHQ checked Sep 5, 2026201-50077

“Sembi empowers organizations with world-class solutions for product quality and security management.”

Source: company website · checked Sep 5, 2026
11
Atser Systems, INCStrong evidence
Houston, TX, United StatesHQ checked Sep 5, 202651-20077

“In the early 1990’s, ATSER pioneered the use of an electronic software solution for Quality Assurance verification and compliance oversight for use in the Civil Engineering…”

Source: company website · checked Sep 5, 2026
12
IntellectPartial evidence
Los Angeles, CA, United StatesHQ checked Sep 5, 202651-20075

“Intellect is an AI-powered enterprise platform that helps manufacturers and life sciences organizations improve quality, compliance, and supply chain visibility.”

Source: company website · checked Sep 5, 2026
13
Qualityze INCStrong evidence
Tampa, FL, United StatesHQ checked Sep 5, 202651-20075

Qualityze is a leading provider of AI-powered, cloud-based Quality Management System (QMS) software for Life Sciences and Manufacturing organizations.”

Source: company website · checked Sep 5, 2026
14
Aces Quality ManagementStrong evidence
Denver, CO, United StatesHQ checked Sep 5, 202651-20073

“ACES Quality Management is the leading provider of enterprise quality management and control software for the financial services industry.”

Source: company website · checked Sep 5, 2026
15
AssurxStrong evidence
Reno, NV, United StatesHQ checked Sep 5, 202651-20046

“With decades of expertise built into our quality management software and regulatory compliance software platforms, AssurX helps companies maintain quality and compliance…”

Source: company website · checked Sep 5, 2026
16
Quality Auditing LLCStrong evidence
Minneapolis, MN, United StatesHQ checked Sep 5, 202611-5043

Quality Auditing LLC is the industry leader in Quality Management System Auditing & Consulting for clients in highly-regulated industries, including Medical Device…”

Source: company website · checked Sep 5, 2026
17
High QAPartial evidence
Hazlet, NJ, United StatesHQ checked Sep 5, 202611-5041

“Is your manufacturing quality process up to standard?”

Source: company website · checked Sep 5, 2026
18Tampa, FL, United StatesHQ checked Sep 5, 202651-20036

“Pilgrim Quality Solutions, an IQVIA company, is the leader in quality and compliance management software and services for the life sciences industry.”

Source: company website · checked Sep 5, 2026
19
SG Systems GlobalIndirect evidence
Dallas, TX, United StatesHQ checked Sep 5, 202651-20036

“V5 MES & QMS: The Ultimate Compliance & Traceability Solution for Regulated Manufacturing At SG Systems Global, we provide cutting-edge Manufacturing Execution Systems (MES) and…”

Source: company website · checked Sep 5, 2026
20
Qameta SoftwareStrong evidence
Fairfax, VA, United StatesHQ checked Sep 5, 202611-5034

“Here at Qameta Software, we work hard to deliver the best software quality solutions for professionals.”

Source: company website · checked Sep 5, 2026
21Dayton, OH, United StatesHQ checked Sep 5, 202611-5031

“Lighthouse, an Inc.”

Source: company website · checked Sep 5, 2026
22
Epsilon3Partial evidence
Los Angeles, CA, United StatesHQ checked Sep 5, 202611-5029

“Every piece of hardware is powered by software, built with software, operated by software.”

Source: company website · checked Sep 5, 2026
23
Enlil, INCIndirect evidence
Campbell, CA, United StatesHQ checked Sep 5, 202611-5026

“Enlil enables MedTech incubators and product companies to ideate, build, and commercialize their regulated innovations faster.”

Source: company website · checked Sep 5, 2026
24Houston, TX, United StatesHQ checked Sep 5, 202611-5026

“We are a software development company specializing in creating management systems that comply with standards such as ISO ISO and AS 9100.”

Source: company website · checked Sep 5, 2026
25
PQ SystemsPartial evidence
Dayton, OH, United StatesHQ checked Sep 5, 202611-5024

“Since 1984, PQ Systems has been providing solutions to help organizations implement quality improvement programs and demonstrate proof of their quality performance.”

Source: company website · checked Sep 5, 2026

Showing 25 of 172 quality management software companies based in the United States

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Quality management software companies based in the United States at a glance

As of Sep 5, 2026
11-50Median size (employees)
HoustonLargest hub · 4 HQs
1,110Contacts with mobile numbers
Sep 5, 2026Data refreshed

Companies by employee count

1-10
82
11-50
59
51-200
19
201-500
6
501-1,000
5
5,001-10,000
1

Verified emails by last verification

0–30
1,144
31–60
68
61–90
2
90–180
1
180+
4

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among quality management software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “quality management software companies”. Matching reads each company's description, not its industry code or its name.
What we exclude
Companies whose own description does not clearly place them among quality management software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,219 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

How many quality management software companies are there based in the United States?

RevenueBase identified 172 quality management software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Caliber Technologies, headquartered in Pittsburgh, tops this list with the largest team on record.

Which city has the most quality management software companies?

Houston leads with 4 headquartered companies, followed by Indianapolis (4) and Los Angeles (4).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,219 verified decision-maker contacts tracked across these 172 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.