Company lists · Data refreshed September 2026

Top 25 Protein misfolding disorder companies based in the United States

RevenueBase identified 67 company matches for protein misfolding disorder companies associated with the United States as of September 2026 and tracks 972 professional contacts across them, including 589 with verified work emails. San Diego is the largest hub.

This list covers company matches for protein misfolding disorder companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 20, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 20, 2026 How this list was built
67Companies
972Contacts tracked
589Verified emails
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The 25 largest protein misfolding disorder companies based in the United States

Ranked by team size
Top 25 of 67 company matches for protein misfolding disorder companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 20, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 20, 202651-200192 contacts →

Exact match

“We are a late-stage clinical biotechnology company with a mission to make degenerative brain disorders history.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
2Exact matchCambridge, MA, United StatesHQ recorded Sep 20, 202651-20071 contacts →

Exact match

“At QurAlis, we are neuro pioneers on a quest to cure, boldly seeking to translate scientific breakthroughs into powerful precision medicines.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
3Exact matchBoston, VA, United StatesHQ recorded Sep 20, 202651-20062 contacts →

Exact match

“Acumen is forging a new path towards safe and effective treatments for Alzheimer’s disease and other neurodegenerative diseases through our focus on the biology of toxic soluble…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
4Exact matchSeattle, WA, United StatesHQ recorded Sep 20, 202611-5036 contacts →

Exact match

“AltPep develops early disease-modifying treatments and detection tools for amyloid diseases by targeting one of the earliest molecular triggers – toxic soluble oligomers.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
5Exact matchChicago, IL, United StatesHQ recorded Sep 20, 202611-5035 contacts →

Exact match

“Vanqua Bio is helping usher in a new era of hope for the millions of people living with neurodegenerative diseases.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
6Exact matchCambridge, MA, United StatesHQ recorded Sep 20, 202611-5034 contacts →

Exact match

“Sunbird Bio is enabling precision neurology through the development of SunbirdDx, a comprehensive blood-based diagnostic platform designed to support earlier, more accurate…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
7Exact matchBethesda, MD, United StatesHQ recorded Sep 20, 202611-5031 contacts →

Exact match

“Gain Therapeutics, Inc.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
8Exact matchRockville, MD, United StatesHQ recorded Sep 20, 202611-5028 contacts →

Exact match

“SciNeuro Pharmaceuticals is a clinical-stage biotechnology company focused on developing groundbreaking therapies for neurodegenerative diseases.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
9Exact matchFramingham, MA, United StatesHQ recorded Sep 20, 202611-5027 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
10Exact matchSan Carlos, CA, United StatesHQ recorded Sep 20, 20261-1024 contacts →

Exact match

“Glycomine is developing orphan drugs for serious rare disorders of metabolism and protein misfolding for which no other therapeutic options exist.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
11Exact matchSan Diego, CA, United StatesHQ recorded Sep 20, 202611-5024 contacts →

Exact match

“Protego Biopharma is a San Diego-based biotech company focused on developing small-molecule drugs that target protein misfolding pathways.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
12Exact matchBillerica, MA, United StatesHQ recorded Sep 20, 202651-20022 contacts →

Exact match

“Sengenics is a functional proteomics company that leverages its patented KREX protein folding technology to discover autoantibody biomarker signature for drug response prediction…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
13Exact matchCambridge, MA, United StatesHQ recorded Sep 20, 202611-5020 contacts →

Exact match

“ProMIS Neurosciences is a clinical-stage biotechnology company committed to the discovery and development of therapeutic antibodies selective for toxic oligomers associated with…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
14Exact matchNew York, NY, United StatesHQ recorded Sep 20, 202611-5020 contacts →

Exact match

“Seed Therapeutics is pioneering the science of improving human health by creating “molecular glues”: novel therapeutics that degrade disease-causing proteins that have heretofore…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
15Exact matchJupiter, FL, United StatesHQ recorded Sep 20, 202611-5018 contacts →

Exact match

“Expansion Therapeutics is a drug discovery and development company pursuing the vast potential of small molecule medicines for RNA-mediated diseases.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
16Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 20, 20261-1018 contacts →

Exact match

“At Apertor we have developed a new class of therapeutics to address one of the toughest challenges in drug discovery, selective disruption of disease-causing protein-protein…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
17Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 20, 20261-1018 contacts →

Exact match

“Acelot is treating functional protein misfolding diseases where the appropriate therapeutic mechanism is a restoration of the normal protein homeostasis.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
18Exact matchSan Carlos, CA, United StatesHQ recorded Sep 20, 202611-5017 contacts →

Exact match

“It’s time to think again about therapies for neurodegenerative disease.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
19Exact matchSunnyvale, CA, United StatesHQ recorded Sep 20, 202611-5016 contacts →

Exact match

“Cantabio Pharmaceuticals Inc.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
20Exact matchSouth San Francisco, CA, United StatesHQ recorded Sep 20, 202611-5015 contacts →

Exact match

“Initial Therapeutics is discovering and developing a new class of small-molecule medicines designed to halt pathogenic protein formation in the earliest stages.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
21Exact matchCambridge, MA, United StatesHQ recorded Sep 20, 202611-5014 contacts →

Exact match

“Aquinnah Pharmaceuticals is focused on a new area of research and development to modulate neurodegenerative stress granules, believed to be important in the pathology of…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
22Exact matchBoston, MA, United StatesHQ recorded Sep 20, 202611-5013 contacts →

Exact match

“Nereid Therapeutics, an ATP company, is discovering new disease treatments using proprietary state-of-the-art technologies for generating, visualizing, and measuring liquid-liquid…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
23Exact matchThousand Oaks, CA, United StatesHQ recorded Sep 20, 20261-1012 contacts →

Exact match

“Preclinical biotechnology company leveraging proprietary structure-based technology to develop small molecule disaggregators and inhibitors targeting previously undruggable…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
24Exact matchMalvern, PA, United StatesHQ recorded Sep 20, 20261-1011 contacts →

Exact match

“Annovis Bio (NYSE: ANVS) is a Phase 3 clinical-stage biotechnology company pioneering a new paradigm for treating chronic and acute neurodegenerative diseases, addressing one of…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
25Exact matchBoston, MA, United StatesHQ recorded Sep 20, 20261-1011 contacts →

Exact match

“WaveBreak is a biopharmaceutical company focused on transforming drug discovery for neurodegenerative diseases, targeting the fleeting protein intermediates central to many…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase

Showing 25 of 67 protein misfolding disorder companies based in the United States

See the full list, filter by size, metro and specialty, and access 589 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Protein misfolding disorder companies based in the United States at a glance

As of Sep 20, 2026
60.6%Verified-email coverage
14.5Average contacts per company
1-10Median size (employees)
7.5%Largest-city concentration · San Diego
Sep 20, 2026Page data refreshed

Companies by employee count

1-10
40
11-50
21
51-200
6

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 67 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “protein misfolding disorder companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 589 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “protein misfolding disorder companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many protein misfolding disorder companies are there based in the United States?

RevenueBase identified 67 company matches for protein misfolding disorder companies associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

Alector tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most protein misfolding disorder companies?

San Diego leads with 5 company records, followed by Boston (4) and Cambridge (4).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 589 professional contacts with verified work emails tracked across these 67 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.