Company lists · Data refreshed September 2026

Top 25 Protein engineering companies based in the United States

RevenueBase identified 159 protein engineering companies headquartered in the United States as of September 2026 and tracks 3,746 professional contacts across them, including 1,980 with verified work emails. San Diego is the largest hub.

This list covers protein engineering companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
159Companies
3,746Contacts tracked
1,980Verified emails
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The 25 largest protein engineering companies based in the United States

Ranked by team size
Top 25 of 159 protein engineering companies based in the United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to protein engineering companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceBethlehem, PA, United StatesHQ checked Sep 16, 2026501-1,000430 contacts →

Indirect evidence

“ABEC engineered solutions and services for biotech manufacturing Since 1974, ABEC has been a global leader in delivering integrated process solutions and services for…”

Source: RevenueBase Database · checked Sep 16, 2026
2Indirect evidenceBoulder, CO, United StatesHQ checked Sep 16, 202651-200228 contacts →

Indirect evidence

“Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.”

Source: RevenueBase Database · checked Sep 16, 2026
3Partial evidenceLebanon, NH, United StatesHQ checked Sep 16, 202651-200150 contacts →

Partial evidence

“Adimab is the most successful antibody discovery and engineering company in the industry and the partner of choice for biopharma.”

Source: RevenueBase Database · checked Sep 16, 2026
4Indirect evidenceNewark, CA, United StatesHQ checked Sep 16, 2026201-500140 contacts →

Indirect evidence

“Vector Laboratories serves and partners with scientists and industry teams developing the next generation of diagnostics, therapeutics, and biological insights.”

Source: RevenueBase Database · checked Sep 16, 2026
5Partial evidencePhiladelphia, PA, United StatesHQ checked Sep 16, 202651-200138 contacts →

Partial evidence

“Integral Molecular is a research-driven biotechnology company specializing in antibodies, viruses, and membrane proteins.”

Source: RevenueBase Database · checked Sep 16, 2026
6Indirect evidenceNewark, CA, United StatesHQ checked Sep 16, 202651-200122 contacts →

Indirect evidence

“ATUM is an industry-leading provider of life science tools and solutions.”

Source: RevenueBase Database · checked Sep 16, 2026
7Indirect evidenceFremont, CA, United StatesHQ checked Sep 16, 202651-20096 contacts →

Indirect evidence

“AnaSpec, a subsidiary of Kaneka Eurogentec, is a globally recognized biotechnology company that manufactures and sells custom and catalog Peptides, Fluorogenic and FRET Assay…”

Source: RevenueBase Database · checked Sep 16, 2026
8Partial evidenceSeattle, WA, United StatesHQ checked Sep 16, 202651-20079 contacts →

Partial evidence

“Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…”

Source: RevenueBase Database · checked Sep 16, 2026
9Partial evidenceBoston, MA, United StatesHQ checked Sep 16, 202611-5039 contacts →

Partial evidence

“Boston-based AI Proteins is a biotech company on a mission to re-imagine protein therapeutics with a novel approach for designing entirely new proteins.”

Source: RevenueBase Database · checked Sep 16, 2026
10Indirect evidenceLakewood, NJ, United StatesHQ checked Sep 16, 202651-20036 contacts →

Indirect evidence

“Worthington is a privately owned, ISO9001 Certified.”

Source: RevenueBase Database · checked Sep 16, 2026
11Indirect evidenceBerkeley, CA, United StatesHQ checked Sep 16, 202611-5035 contacts →

Indirect evidence

“We envision a world where we continuously, sustainably, and affordably improve human life with biocatalysis.”

Source: RevenueBase Database · checked Sep 16, 2026
12Partial evidenceNew York, NY, United StatesHQ checked Sep 16, 202611-5032 contacts →

Partial evidence

“At Neochromosome, we enable biological engineering at a genome-scale.”

Source: RevenueBase Database · checked Sep 16, 2026
13Partial evidenceSeattle, WA, United StatesHQ checked Sep 16, 202611-5031 contacts →

Partial evidence

“Monod Bio is a pioneer company in the design of de novo protein biosensors.”

Source: RevenueBase Database · checked Sep 16, 2026
14Indirect evidenceJupiter, FL, United StatesHQ checked Sep 16, 202611-5029 contacts →

Indirect evidence

“Alphazyme was founded in 2018 by Christopher Benoit, Stephana Petrino and Chad Decker.”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidenceNew York, NY, United StatesHQ checked Sep 16, 202611-5026 contacts →

Indirect evidence

“Ordaōs is a human-enabled, machine-driven drug design company.”

Source: RevenueBase Database · checked Sep 16, 2026
16Indirect evidenceAthens, United StatesHQ checked Sep 16, 202611-5025 contacts →

Indirect evidence

“Athens Research and Technology, Inc.(ART) is a dynamic life science company and recipient of the Globe Award as Georgia’s 2022 Exporter of the Year.”

Source: RevenueBase Database · checked Sep 16, 2026
17Partial evidenceSeattle, WA, United StatesHQ checked Sep 16, 202611-5024 contacts →

Partial evidence

“Archon is a biotechnology company developing computationally designed proteins to unlock powerful therapeutic targets that lie beyond the reach of existing modalities and to…”

Source: RevenueBase Database · checked Sep 16, 2026
18Partial evidenceSeattle, WA, United StatesHQ checked Sep 16, 202611-5024 contacts →

Partial evidence

“Cyrus Biotechnology is a pre-clinical-stage biotech company combining protein design and screening to create novel biologics for serious unmet medical needs.”

Source: RevenueBase Database · checked Sep 16, 2026
19Indirect evidenceSan Leandro, CA, United StatesHQ checked Sep 16, 20261-1023 contacts →

Indirect evidence

“Geltor is the biodesign company that audaciously imagines and deeply explores all the possibilities that the tree of life has to offer.”

Source: RevenueBase Database · checked Sep 16, 2026
20Indirect evidenceAnn Arbor, MI, United StatesHQ checked Sep 16, 202611-5022 contacts →

Indirect evidence

“At Ambient Biosciences, we are dedicated to being a true partner in your success.”

Source: RevenueBase Database · checked Sep 16, 2026
21Indirect evidence​columbus, GA, United StatesHQ checked Sep 16, 202651-20022 contacts →

Indirect evidence

“HPPE produces the next generation of high performance and cost competitive biopolymer-based products.”

Source: RevenueBase Database · checked Sep 16, 2026
22Partial evidenceDenver, CO, United StatesHQ checked Sep 16, 202611-5021 contacts →

Partial evidence

“Ascent Protein is the new benchmark in protein purity.”

Source: RevenueBase Database · checked Sep 16, 2026
23Indirect evidenceMilwaukee, WI, United StatesHQ checked Sep 16, 202651-20017 contacts →

Indirect evidence

“Founded in 1985 in Milwaukee, Wisconsin, Molecular Biology Resources, Inc.(MBR) has earned the reputation as a world leader in biochemical manufacturing.”

Source: RevenueBase Database · checked Sep 16, 2026
24Partial evidenceSouth San Francisco​, CA, United StatesHQ checked Sep 16, 20261-1017 contacts →

Partial evidence

“CHO Plus is creating regulatory compliant genetically engineered mammalian cells to be used by biopharmaceutical companies for therapeutic protein manufacturing.”

Source: RevenueBase Database · checked Sep 16, 2026
25Partial evidencePalo Alto, CA, United StatesHQ checked Sep 16, 202611-5016 contacts →

Partial evidence

“Avenue Biosciences is a biotechnology company dedicated to accelerating the discovery and development of protein biologics, so that no life-saving therapy goes unrealized because…”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 159 protein engineering companies based in the United States

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Protein engineering companies based in the United States at a glance

As of Sep 16, 2026
52.9%Verified-email coverage
23.6Average contacts per company
1-10Median size (employees)
5.0%Largest-city concentration · San Diego
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
84
11-50
50
51-200
14
201-500
7
501-1,000
4

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 159 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among protein engineering companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “protein engineering companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names protein engineering companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among protein engineering companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 1,980 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names protein engineering companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many protein engineering companies are there based in the United States?

RevenueBase identified 159 protein engineering companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

ABEC, headquartered in Bethlehem, tops this list with the largest team on record.

Which city has the most protein engineering companies?

San Diego leads with 8 headquartered companies, followed by Boston (7) and Seattle (7).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,980 verified decision-maker contacts tracked across these 159 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.