Company lists · Data refreshed September 2026

Top 25 Prior authorization software companies based in the United States

RevenueBase identified 132 prior authorization software companies headquartered in the United States as of September 2026 and tracks 5,574 professional contacts across them, including 2,650 with verified work emails and 2,824 with mobile numbers. San Francisco is the largest hub.

This list covers prior authorization software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
132Companies
5,574Contacts tracked
2,650Verified emails
2,824Mobile numbers
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The 25 largest prior authorization software companies based in the United States

Ranked by team size
Top 25 of 132 prior authorization software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names prior authorization software companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#CompanyHeadquartersEmployeesContacts
1
WaystarPartial evidence
Louisville, KY, United StatesHQ checked Sep 5, 20261,001-5,0001,586

“Waystar’s enterprise-grade software is purpose-built to simplify healthcare payments.”

Source: company website · checked Sep 5, 2026
2Teaneck, NJ, United StatesHQ checked Sep 5, 202610001+968

“Cognizant (Nasdaq-100: CTSH) is one of the world's leading professional services companies, transforming clients' business, operating and technology models for the digital era.”

Source: company website · checked Sep 5, 2026
3Tempe, AZ, United StatesHQ checked Sep 5, 20261,001-5,000614

“Centauri Health Solutions aims to attract and retain the industry’s top talent as we continue to create and deliver the most flexible and innovative tools in the market.”

Source: company website · checked Sep 5, 2026
4
MHKIndirect evidence
Tampa, FL, United StatesHQ checked Sep 5, 2026201-500270

“MHK, part of the Hearst Health network, improves compliance, efficiency and quality for health plans, pharmacy benefit managers and other managed care organizations.”

Source: company website · checked Sep 5, 2026
5
AgadiaIndirect evidence
Parsippany, NJ, United StatesHQ checked Sep 5, 202651-200116

“Agadia is a leading healthcare management technology company addressing the evolving needs of the managed care market with a suite of utilization management solutions in…”

Source: company website · checked Sep 5, 2026
6
Md-StaffPartial evidence
Temecula, CA, United StatesHQ checked Sep 5, 202651-200102

“Founded in 1982 and headquartered in Temecula, CA, Applied Statistics & Management, Inc.(ASM) is dedicated to the development and support of software solutions that leverage the…”

Source: company website · checked Sep 5, 2026
7
DosespotIndirect evidence
Boston, MA, United StatesHQ checked Sep 5, 202651-20087

“DoseSpot delivers best-in-class e-prescribing, insurance verification, and revenue cycle management solutions for healthcare providers, improving price transparency and outcomes…”

Source: company website · checked Sep 5, 2026
8
Plexis Healthcare SystemsIndirect evidence
Medford, OR, United StatesHQ checked Sep 5, 202651-20087

“PLEXIS Healthcare Systems is a leading payer technology company delivering trusted enterprise core administration and claims management solutions to healthcare payers and delivery…”

Source: company website · checked Sep 5, 2026
9
Humata HealthStrong evidence
Winter Park, FL, United StatesHQ checked Sep 5, 202651-20081

“At Humata, we’re expanding the definition of “prior authorization” and solving for the full clinical clearance lifecycle – so that patients can get the care they need and deserve…”

Source: company website · checked Sep 5, 2026
10
RialticIndirect evidence
Atlanta, GA, United StatesHQ checked Sep 5, 202651-20076

“We’re on a mission to make healthcare more efficient.”

Source: company website · checked Sep 5, 2026
11Phoenix, AZ, United StatesHQ checked Sep 5, 202651-20073

“Founded in 1981, Eldorado is an industry leader in payer platform innovation and enterprise automation as evidence by our 80+ HEALTHpac and Javelina clients nationwide.”

Source: company website · checked Sep 5, 2026
12
Santech Solution, INCIndirect evidence
Princeton, NJ, United StatesHQ checked Sep 5, 202651-20068

“Santech is a Delaware Corporation headquartered in New Jersey.”

Source: company website · checked Sep 5, 2026
13Waltham, MA, United StatesHQ checked Sep 5, 202651-20066

“Commure Care (formerly known as PatientKeeper Clinical Workflow Solutions) and Commure Perform (formerly known as PatientKeeper Revenue Integrity Solution) are now part of…”

Source: company website · checked Sep 5, 2026
14
EcaresoftIndirect evidence
Austin, TX, United StatesHQ checked Sep 5, 202651-20061

“At Ecaresoft Inc.”

Source: company website · checked Sep 5, 2026
15
LatentIndirect evidence
San Francisco, CA, United StatesHQ checked Sep 5, 202651-20059

“Latent is the leading Enterprise Pharmacy Intelligence platform, powered by a clinical agentic engine enables health systems to serve more patients, grow their pharmacy operation…”

Source: company website · checked Sep 5, 2026
16
RHYMEStrong evidence
Columbus, OH, United StatesHQ checked Sep 5, 202651-20059

“Rhyme makes prior authorizations fully touchless.”

Source: company website · checked Sep 5, 2026
17Boca Raton, FL, United StatesHQ checked Sep 5, 202651-20048

“Ringmaster is a cloud-based healthcare solutions provider created to simplify and enhance administrative processes by utilizing cutting edge technologies.”

Source: company website · checked Sep 5, 2026
18
Ingenia HealthPartial evidence
Boston, MA, United StatesHQ checked Sep 5, 202651-20046

“We revolutionize your operations with our innovative healthcare software solutions, empowering payers and providers to conduct fact-based operations, effectively manage members…”

Source: company website · checked Sep 5, 2026
19
SamacareStrong evidence
San Francisco, CA, United StatesHQ checked Sep 5, 202651-20045

“We've built a Script-to-Therapy platform to streamline the prior authorization process for for life-changing specialty medications.”

Source: company website · checked Sep 5, 2026
20
Banjo HealthStrong evidence
Washington, DC, United StatesHQ checked Sep 5, 202611-5041

“Banjo Health is a prior authorization decision support platform for health plans and pharmacy benefit managers (collectively “payers”).”

Source: company website · checked Sep 5, 2026
21
SILNAIndirect evidence
New York, NY, United StatesHQ checked Sep 5, 202651-20036

“Introducing the industry's first Care Readiness Platform.”

Source: company website · checked Sep 5, 2026
22
Parx SolutionsStrong evidence
Burlington, MA, United StatesHQ checked Sep 5, 202611-5031

Prior Authorization Support System Improving and simplifing the prior authorization process for providers, office staff and patients.”

Source: company website · checked Sep 5, 2026
23
5-Tek MedicalIndirect evidence
Washington, DC, United StatesHQ checked Sep 5, 202611-5031

“Welcome to 5-Tek Medical, a leading healthcare technology company dedicated to optimizing providers’ back offices and ensuring their success.”

Source: company website · checked Sep 5, 2026
24
CenterxIndirect evidence
Madison, WI, United StatesHQ checked Sep 5, 202611-5027

“CenterX, which is a part of Cencora, offers complete prescription decision support solutions that help health systems reduce spend, increase revenue, and improve medication…”

Source: company website · checked Sep 5, 2026
25
EthermedStrong evidence
Philadelphia, PA, United StatesHQ checked Sep 5, 202611-5026

“Ethermed is solving prior authorization and stitching together the healthcare ecosystem.”

Source: company website · checked Sep 5, 2026

Showing 25 of 132 prior authorization software companies based in the United States

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Prior authorization software companies based in the United States at a glance

As of Sep 5, 2026
11-50Median size (employees)
San FranciscoLargest hub · 9 HQs
2,824Contacts with mobile numbers
Sep 5, 2026Data refreshed

Companies by employee count

1-10
46
11-50
48
51-200
31
201-500
2
1,001-5,000
3
10001+
2

Verified emails by last verification

0–30
2,488
31–60
143
61–90
1
90–180
1
180+
17

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among prior authorization software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “prior authorization software companies”. Matching reads each company's description, not its industry code or its name.
What we exclude
Companies whose own description does not clearly place them among prior authorization software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 2,650 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

How many prior authorization software companies are there based in the United States?

RevenueBase identified 132 prior authorization software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Waystar, headquartered in Louisville, tops this list with the largest team on record.

Which city has the most prior authorization software companies?

San Francisco leads with 9 headquartered companies, followed by New York (6) and Boston (4).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 2,650 verified decision-maker contacts tracked across these 132 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.