Company lists · Data refreshed September 2026

Top 25 Prescription drug insurance plans based in the United States

RevenueBase identified 212 prescription drug insurance plans headquartered in the United States as of September 2026 and tracks 26,535 professional contacts across them, including 11,662 with verified work emails. New York is the largest hub.

This list covers prescription drug insurance plans headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 17, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 17, 2026 86% judged on-target in blind review
212Companies
26,535Contacts tracked
11,662Verified emails
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The 25 largest prescription drug insurance plans based in the United States

Ranked by team size
Top 25 of 212 prescription drug insurance plans based in the United States, ranked by team size, largest first. Data refreshed Sep 17, 2026. RevenueBase Smart Search rates how each company's information relates to prescription drug insurance plans: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Strong evidenceSt. Louis, MO, United StatesHQ checked Sep 17, 202610001+12,078 contacts →

Strong evidence

“Through Express Scripts Pharmacy Benefit Services, we create and manage innovative prescription benefit offerings to lower costs for members, health plans, employers, labor unions…”

Source: RevenueBase Database · checked Sep 17, 2026
2Indirect evidenceEagan, NE, United StatesHQ checked Sep 17, 20265,001-10,0005,822 contacts →

Indirect evidence

“Prime Therapeutics LLC (Prime) is a diversified pharmacy solutions organization.”

Source: RevenueBase Database · checked Sep 17, 2026
3Partial evidenceSan Diego, CA, United StatesHQ checked Sep 17, 20261,001-5,0001,802 contacts →

Partial evidence

“MedImpact is the nation’s largest independent health solutions and pharmacy benefit company, serving commercial health plans, government programs, self insured/employer groups…”

Source: RevenueBase Database · checked Sep 17, 2026
4Partial evidenceSanta Monica, United StatesHQ checked Sep 17, 2026501-1,000989 contacts →

Partial evidence

“GoodRx started in 2011 to make prescription pricing more transparent.”

Source: RevenueBase Database · checked Sep 17, 2026
5Indirect evidenceSchaumburg, IL, United StatesHQ checked Sep 17, 20265,001-10,000748 contacts →

Indirect evidence

“Catamaran is now OptumRx.”

Source: RevenueBase Database · checked Sep 17, 2026
6Indirect evidencePlano, TX, United StatesHQ checked Sep 17, 2026501-1,000361 contacts →

Indirect evidence

“Avita is committed to promoting health equities by providing comprehensive, compassionate, and inclusive care.”

Source: RevenueBase Database · checked Sep 17, 2026
7Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 17, 20261,001-5,000350 contacts →

Indirect evidence

“Elixir is a pharmacy benefits and services company with the scale, flexibility and expertise to help our clients achieve their unique business goals.”

Source: RevenueBase Database · checked Sep 17, 2026
8Indirect evidencePa, United StatesHQ checked Sep 17, 2026201-500266 contacts →

Indirect evidence

“Formed in PerformRx, LLC is a URAC accredited pharmacy benefits manager servicing lines of business including Medicaid, Medicare, and Commercial markets.”

Source: RevenueBase Database · checked Sep 17, 2026
9Indirect evidenceMontvale, NJ, United StatesHQ checked Sep 17, 2026201-500264 contacts →

Indirect evidence

“EmpiRx Health is the leading clinically-driven pharmacy benefits management (PBM) company that puts the pharmacist at the center of its unique Medication Optimization operating…”

Source: RevenueBase Database · checked Sep 17, 2026
10Indirect evidenceWashington, IN, United StatesHQ checked Sep 17, 2026201-500236 contacts →

Indirect evidence

“True Rx Health Strategists is a pharmacy benefits manager for employee benefit brokers and self-insured employers who refuse to accept the health care paradox: spending more on…”

Source: RevenueBase Database · checked Sep 17, 2026
11Indirect evidencePortland, OR, United StatesHQ checked Sep 17, 2026201-500199 contacts →

Indirect evidence

“The true cost of pharmacy is about much more than the price of the pills.”

Source: RevenueBase Database · checked Sep 17, 2026
12Indirect evidenceGainesville, United StatesHQ checked Sep 17, 2026201-500198 contacts →

Indirect evidence

“ProCare Rx, a privately held leader in pharmacy claims processing, pharmacy benefit management (PBM), and clinical program design, has been empowering healthcare organizations…”

Source: RevenueBase Database · checked Sep 17, 2026
13Partial evidenceDubuque, IA, United StatesHQ checked Sep 17, 202651-200122 contacts →

Partial evidence

“MedOne unlocks the most appropriate prescription at the most affordable price for organizations and their health plan members nationwide.”

Source: RevenueBase Database · checked Sep 17, 2026
14Indirect evidenceWashington, IN, United StatesHQ checked Sep 17, 202651-200119 contacts →

Indirect evidence

“TrueScripts Management Services is a pharmacist-founded, fully-transparent PBM that has focused on revolutionizing the pharmacy benefit management industry since our beginning in…”

Source: RevenueBase Database · checked Sep 17, 2026
15Strong evidenceEast Syracuse, NY, United StatesHQ checked Sep 17, 20261,001-5,000108 contacts →

Strong evidence

“At ProAct, we strive to produce innovative, affordable and flexible prescription drug benefit solutions for the client by combining industry leading client service with the latest…”

Source: RevenueBase Database · checked Sep 17, 2026
16Partial evidenceOrlando, FL, United StatesHQ checked Sep 17, 20261,001-5,000102 contacts →

Partial evidence

“We provide total drug management, combining innovative tools and Pharmacy Benefit Management (PBM) expertise, with the capabilities and experience of a comprehensive specialty…”

Source: RevenueBase Database · checked Sep 17, 2026
17Indirect evidenceKansas City, MO, United StatesHQ checked Sep 17, 202651-20097 contacts →

Indirect evidence

“Tria Health, a Stellus Rx company, provides personalized, pharmacist-led support that helps people get the most from their medications and achieve better health.”

Source: RevenueBase Database · checked Sep 17, 2026
18Indirect evidenceSt Louis, MO, United StatesHQ checked Sep 17, 202651-20081 contacts →

Indirect evidence

“SHARx (pronounced “sharks”) was designed to serve the uninsured and underinsured populations that are struggling to afford life-altering and lifesaving medications.”

Source: RevenueBase Database · checked Sep 17, 2026
19Indirect evidenceBuffalo, NY, United StatesHQ checked Sep 17, 202651-20078 contacts →

Indirect evidence

“At Pharmacy Benefits Dimensions, we understand the complexities of managing pharmacy benefits while prioritizing cost savings, high-quality care, and a seamless experience for our…”

Source: RevenueBase Database · checked Sep 17, 2026
20Indirect evidenceBeaumont, TX, United StatesHQ checked Sep 17, 202651-20075 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 17, 2026
21Partial evidenceFresno, CA, United StatesHQ checked Sep 17, 202651-20065 contacts →

Partial evidence

“US Script provides clinically sound and fiscally responsible prescription benefit programs that enhance quality of care.”

Source: RevenueBase Database · checked Sep 17, 2026
22Indirect evidenceBoca Raton, FL, United StatesHQ checked Sep 17, 202651-20060 contacts →

Indirect evidence

“SlateRx has been listening to what employers, plan sponsors, and brokers have been saying about traditional pharmacy benefit management-it’s time for something new.”

Source: RevenueBase Database · checked Sep 17, 2026
23Partial evidenceAustin, TX, United StatesHQ checked Sep 17, 202651-20056 contacts →

Partial evidence

Prescription Lifeline is a prescription advocacy company that helps low-income, uninsured Americans obtain their expensive prescription medication directly through pharmaceutical…”

Source: RevenueBase Database · checked Sep 17, 2026
24Strong evidenceWashington, United StatesHQ checked Sep 17, 202611-5049 contacts →

Strong evidence

“The Pharmaceutical Care Management Association (PCMA) is the national association representing America’s pharmacy benefit companies (PBCs) PBCs administer prescription drug plans…”

Source: RevenueBase Database · checked Sep 17, 2026
25Strong evidenceDallas, TX, United StatesHQ checked Sep 17, 2026201-50048 contacts →

Strong evidence

“VerusRx is an industry leading pharmacy benefits manager focused on helping employers manage their prescription drug costs while improving health outcomes for their employees.”

Source: RevenueBase Database · checked Sep 17, 2026

Showing 25 of 212 prescription drug insurance plans based in the United States

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Prescription drug insurance plans based in the United States at a glance

As of Sep 17, 2026
43.9%Verified-email coverage
125.2Average contacts per company
11-50Median size (employees)
2.8%Largest-city concentration · New York
Sep 17, 2026Page data refreshed

Companies by employee count

1-10
76
11-50
83
51-200
26
201-500
12
501-1,000
3
1,001-5,000
7
5,001-10,000
2
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 212 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among prescription drug insurance plans, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “prescription drug insurance plans”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names prescription drug insurance plans), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among prescription drug insurance plans, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 11,662 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 17, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names prescription drug insurance plans, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many prescription drug insurance plans are there based in the United States?

RevenueBase identified 212 prescription drug insurance plans headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Express Scripts Pharmacy Benefit Services, headquartered in St. Louis, tops this list with the largest team on record.

Which city has the most prescription drug insurance plans?

New York leads with 6 headquartered companies, followed by Austin (5) and Las Vegas (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 11,662 verified decision-maker contacts tracked across these 212 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 17, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.