Company lists · Data refreshed September 2026

Top 25 Prescription drug insurance companies based in the United States

RevenueBase identified 417 prescription drug insurance companies headquartered in the United States as of September 2026 and tracks 54,358 professional contacts across them, including 21,931 with verified work emails. New York is the largest hub.

This list covers prescription drug insurance companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 16, 2026 86% judged on-target in blind review
417Companies
54,358Contacts tracked
21,931Verified emails
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The 25 largest prescription drug insurance companies based in the United States

Ranked by team size
Top 25 of 417 prescription drug insurance companies based in the United States, ranked by team size, largest first. Data refreshed Sep 16, 2026. RevenueBase Smart Search rates how each company's information relates to prescription drug insurance companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceSt. Louis, MO, United StatesHQ checked Sep 16, 202610001+12,078 contacts →

Partial evidence

“Through Express Scripts Pharmacy Benefit Services, we create and manage innovative prescription benefit offerings to lower costs for members, health plans, employers, labor unions…”

Source: RevenueBase Database · checked Sep 16, 2026
2Indirect evidenceEagan, NE, United StatesHQ checked Sep 16, 20265,001-10,0005,822 contacts →

Indirect evidence

“Prime Therapeutics LLC (Prime) is a diversified pharmacy solutions organization.”

Source: RevenueBase Database · checked Sep 16, 2026
3Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 16, 202610001+5,277 contacts →

Indirect evidence

“At AmeriHealth Caritas, we’re passionate about helping people get care, stay well, and build healthy communities.”

Source: RevenueBase Database · checked Sep 16, 2026
4Strong evidenceSt. Louis, MO, United StatesHQ checked Sep 16, 20265,001-10,0004,965 contacts →

Strong evidence

“For more than 20 years, Wellcare has offered a range of Medicare products, including Medicare Advantage and Medicare Prescription Drug Plans (PDP), which offer affordable coverage…”

Source: RevenueBase Database · checked Sep 16, 2026
5Indirect evidencePittsburgh, PA, United StatesHQ checked Sep 16, 20261,001-5,0004,363 contacts →

Indirect evidence

“How can we best serve our members and the community?”

Source: RevenueBase Database · checked Sep 16, 2026
6Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 16, 20261,001-5,0001,802 contacts →

Indirect evidence

“MedImpact is the nation’s largest independent health solutions and pharmacy benefit company, serving commercial health plans, government programs, self insured/employer groups…”

Source: RevenueBase Database · checked Sep 16, 2026
7Indirect evidenceMadison, WI, United StatesHQ checked Sep 16, 20261,001-5,0001,498 contacts →

Indirect evidence

“Navitus Health Solutions is a pioneering pharmacy solutions provider, having launched one of the first transparent PBMs over 20 years ago.”

Source: RevenueBase Database · checked Sep 16, 2026
8Indirect evidenceSchaumburg, IL, United StatesHQ checked Sep 16, 20265,001-10,000748 contacts →

Indirect evidence

“Catamaran is now OptumRx.”

Source: RevenueBase Database · checked Sep 16, 2026
9Partial evidenceDaytona Beach, FL, United StatesHQ checked Sep 16, 20261,001-5,000551 contacts →

Partial evidence

“Florida Health Care Plans is more than an insurance company.”

Source: RevenueBase Database · checked Sep 16, 2026
10Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 16, 2026501-1,000497 contacts →

Indirect evidence

“Our mission is to reduce the cost and complexity of pharmacy benefits for America’s employers and patients.”

Source: RevenueBase Database · checked Sep 16, 2026
11Indirect evidenceRidgefield Park, NJ, United StatesHQ checked Sep 16, 20261,001-5,000465 contacts →

Indirect evidence

“Providing Excellence in Long-Term Care is Our Specialty.”

Source: RevenueBase Database · checked Sep 16, 2026
12Indirect evidenceFarmington, CT, United StatesHQ checked Sep 16, 2026501-1,000402 contacts →

Indirect evidence

“ConnectiCare is a leading health plan in the state of Connecticut.”

Source: RevenueBase Database · checked Sep 16, 2026
13Indirect evidenceCleveland, OH, United StatesHQ checked Sep 16, 2026501-1,000361 contacts →

Indirect evidence

“ExactCare, a pharmacy by AnewHealth, is a national medication management and pharmacy care provider that helps people with the most complex medical needs live healthier at home.”

Source: RevenueBase Database · checked Sep 16, 2026
14Indirect evidencePlano, TX, United StatesHQ checked Sep 16, 2026501-1,000361 contacts →

Indirect evidence

“Avita is committed to promoting health equities by providing comprehensive, compassionate, and inclusive care.”

Source: RevenueBase Database · checked Sep 16, 2026
15Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 16, 20261,001-5,000350 contacts →

Indirect evidence

“Elixir is a pharmacy benefits and services company with the scale, flexibility and expertise to help our clients achieve their unique business goals.”

Source: RevenueBase Database · checked Sep 16, 2026
16Partial evidenceCastle Rock, CO, United StatesHQ checked Sep 16, 202651-200329 contacts →

Partial evidence

“CVS Health Corporation is an American healthcare company that owns CVS Pharmacy, a retail pharmacy chain; CVS Caremark, a pharmacy benefits manager; and Aetna, a health insurance…”

Source: RevenueBase Database · checked Sep 16, 2026
17Indirect evidenceFargo, United StatesHQ checked Sep 16, 20261,001-5,000319 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 16, 2026
18Indirect evidenceBonita Springs, FL, United StatesHQ checked Sep 16, 2026201-500314 contacts →

Indirect evidence

“Redefining Pharmacy Benefits from the Very Beginning For more than four decades, our family-owned organization has challenged the status quo in pharmacy benefits.”

Source: RevenueBase Database · checked Sep 16, 2026
19Indirect evidencePa, United StatesHQ checked Sep 16, 2026201-500266 contacts →

Indirect evidence

“Formed in PerformRx, LLC is a URAC accredited pharmacy benefits manager servicing lines of business including Medicaid, Medicare, and Commercial markets.”

Source: RevenueBase Database · checked Sep 16, 2026
20Indirect evidenceMontvale, NJ, United StatesHQ checked Sep 16, 2026201-500264 contacts →

Indirect evidence

“EmpiRx Health is the leading clinically-driven pharmacy benefits management (PBM) company that puts the pharmacist at the center of its unique Medication Optimization operating…”

Source: RevenueBase Database · checked Sep 16, 2026
21Indirect evidenceConshohocken, PA, United StatesHQ checked Sep 16, 2026201-500257 contacts →

Indirect evidence

“PharmaForce is a leading provider of innovative pharmacy solutions, specializing in 340B Third Party Administration (TPA) and Pharmacy Benefit Management (PBM) solutions.”

Source: RevenueBase Database · checked Sep 16, 2026
22Indirect evidenceWashington, IN, United StatesHQ checked Sep 16, 2026201-500236 contacts →

Indirect evidence

“True Rx Health Strategists is a pharmacy benefits manager for employee benefit brokers and self-insured employers who refuse to accept the health care paradox: spending more on…”

Source: RevenueBase Database · checked Sep 16, 2026
23Indirect evidenceEast Syracuse, NY, United StatesHQ checked Sep 16, 20261,001-5,000224 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 16, 2026
24Indirect evidencePortland, OR, United StatesHQ checked Sep 16, 2026201-500199 contacts →

Indirect evidence

“The true cost of pharmacy is about much more than the price of the pills.”

Source: RevenueBase Database · checked Sep 16, 2026
25Indirect evidenceGainesville, United StatesHQ checked Sep 16, 2026201-500198 contacts →

Indirect evidence

“ProCare Rx, a privately held leader in pharmacy claims processing, pharmacy benefit management (PBM), and clinical program design, has been empowering healthcare organizations…”

Source: RevenueBase Database · checked Sep 16, 2026

Showing 25 of 417 prescription drug insurance companies based in the United States

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Prescription drug insurance companies based in the United States at a glance

As of Sep 16, 2026
40.3%Verified-email coverage
130.4Average contacts per company
11-50Median size (employees)
2.6%Largest-city concentration · New York
Sep 16, 2026Page data refreshed

Companies by employee count

1-10
163
11-50
142
51-200
56
201-500
26
501-1,000
6
1,001-5,000
14
5,001-10,000
3
10001+
3

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 417 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among prescription drug insurance companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “prescription drug insurance companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names prescription drug insurance companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among prescription drug insurance companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 21,931 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names prescription drug insurance companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many prescription drug insurance companies are there based in the United States?

RevenueBase identified 417 prescription drug insurance companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Express Scripts Pharmacy Benefit Services, headquartered in St. Louis, tops this list with the largest team on record.

Which city has the most prescription drug insurance companies?

New York leads with 11 headquartered companies, followed by Houston (6) and Las Vegas (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 21,931 verified decision-maker contacts tracked across these 417 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.