Company lists · Data refreshed September 2026

Top 25 Prescription compliance software companies based in the United States

RevenueBase identified 208 prescription compliance software companies headquartered in the United States as of September 2026 and tracks 7,697 professional contacts across them, including 3,074 with verified work emails and 3,832 with mobile numbers. Columbus is the largest hub.

This list covers prescription compliance software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
208Companies
7,697Contacts tracked
3,074Verified emails
3,832Mobile numbers
Unlock all 208 companies Free signup · no credit card · 500 free credits

The 25 largest prescription compliance software companies based in the United States

Ranked by team size
Top 25 of 208 prescription compliance software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names prescription compliance software companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#CompanyHeadquartersEmployeesContacts
1
CovermymedsIndirect evidence
Columbus, OH, United StatesHQ checked Sep 5, 20261,001-5,0001,656

“CoverMyMeds, part of McKesson Corporation, is a medication access company committed to helping people get the medicine they need to live healthier lives.”

Source: company website · checked Sep 5, 2026
2
Specialtyrx, INCIndirect evidence
Ridgefield Park, NJ, United StatesHQ checked Sep 5, 20261,001-5,000465

“Providing Excellence in Long-Term Care is Our Specialty.”

Source: company website · checked Sep 5, 2026
3
Drfirst, INCIndirect evidence
Arlington, VA, United StatesHQ checked Sep 5, 2026201-500430

“DrFirst has been transforming medication management for 25 years, helping providers and patients navigate a complex and often fragmented healthcare system.”

Source: company website · checked Sep 5, 2026
4
Parata SystemsIndirect evidence
Durham, NC, United StatesHQ checked Sep 5, 202610001+395

“At Parata, a BD company, we power pharmacies to help people lead healthier lives.”

Source: company website · checked Sep 5, 2026
5
Redsail TechnologiesIndirect evidence
Spartanburg, SC, United StatesHQ checked Sep 5, 2026501-1,000341

“RedSail Technologies builds the technology that independent and long-term care pharmacies need to succeed.”

Source: company website · checked Sep 5, 2026
6
AlixarxIndirect evidence
Plano, TX, United StatesHQ checked Sep 5, 2026501-1,000229

“AlixaRx provides advanced pharmacy services to post‐acute healthcare facilities through a new model that leverages technology to deliver medication therapy management.”

Source: company website · checked Sep 5, 2026
7
Pdx, INCIndirect evidence
Fort Worth, TX, United StatesHQ checked Sep 5, 2026501-1,000225

“A leading provider of healthcare technology for over 30 years to nearly pharmacies nationwide, our 650 person team of developers, design architects, and customer support…”

Source: company website · checked Sep 5, 2026
8
Consonus PharmacyIndirect evidence
Portland, OR, United StatesHQ checked Sep 5, 2026201-500199

“The true cost of pharmacy is about much more than the price of the pills.”

Source: company website · checked Sep 5, 2026
9Irving, TX, United StatesHQ checked Sep 5, 2026201-500172

“PioneerRx Pharmacy Software has a deep understanding of the challenges faced by independent pharmacies.”

Source: company website · checked Sep 5, 2026
10
Transaction Data SystemsIndirect evidence
Orlando, FL, United StatesHQ checked Sep 5, 2026501-1,000165

“For the past 45 years, TDS has been dedicated to the success of independent pharmacy.”

Source: company website · checked Sep 5, 2026
11
ArxiumIndirect evidence
Buffalo Grove, IL, United StatesHQ checked Sep 5, 2026201-500148

“ARxIUM is shaped by innovation and strengthened through partnership to advance pharmacy solutions globally.”

Source: company website · checked Sep 5, 2026
12
Verity SolutionsPartial evidence
Bloomfield, CT, United StatesHQ checked Sep 5, 202651-200137

“Verity Solutions is an award-winning leader in software and services that optimize pharmacy supply chain outcomes for better financial results and patient care.”

Source: company website · checked Sep 5, 2026
13
CodonicsPartial evidence
Cleveland, OH, United StatesHQ checked Sep 5, 202651-200119

“In today’s fast-paced healthcare environment, medication errors, compliance risks, and workflow inefficiencies put patients and providers at risk.”

Source: company website · checked Sep 5, 2026
14
Macro HelixPartial evidence
Atlanta, GA, United StatesHQ checked Sep 5, 2026201-500109

“Macro Helix is focused on assisting pharmacy providers as they strive to improve financial performance, increase operating efficiencies, and maintain regulatory compliance.”

Source: company website · checked Sep 5, 2026
15
Liberty SoftwarePartial evidence
Southlake, TX, United StatesHQ checked Sep 5, 202651-200109

“Liberty Software began as an independent computer service company serving the computer needs of community pharmacies across the South.”

Source: company website · checked Sep 5, 2026
16
3am Technologies, LLCIndirect evidence
Joelton, TN, United StatesHQ checked Sep 5, 202611-50108

“3AM Technologies presents ServeRx and SimServeRx ServeRx™ is a complete medication management system that provides a unique closed loop solution for medication management from…”

Source: company website · checked Sep 5, 2026
17
IntelliguardIndirect evidence
Columbus, OH, United StatesHQ checked Sep 5, 202651-200105

“Intelliguard is a purpose-built healthcare technology company transforming how hospitals manage medications.”

Source: company website · checked Sep 5, 2026
18
primerx.ioIndirect evidence
Uniondale, NY, United StatesHQ checked Sep 5, 202651-20095

“As pharmacists play an increasingly important role in patient care, the need has never been greater for technology-based solutions that add efficiency to operations and facilitate…”

Source: company website · checked Sep 5, 2026
19
DosespotIndirect evidence
Boston, MA, United StatesHQ checked Sep 5, 202651-20087

“DoseSpot delivers best-in-class e-prescribing, insurance verification, and revenue cycle management solutions for healthcare providers, improving price transparency and outcomes…”

Source: company website · checked Sep 5, 2026
20
LspediaStrong evidence
Farmington Hills, MI, United StatesHQ checked Sep 5, 202651-20080

“LSPedia is the leading provider of turnkey FDA (DSCSA) compliance solutions and supply chain software solutions to the pharmaceutical industry.”

Source: company website · checked Sep 5, 2026
21
KeycentrixPartial evidence
Wichita, KS, United StatesHQ checked Sep 5, 202651-20064

“Keycentrix™ is a premier provider of business-enhancing software and technology for pharmacies.”

Source: company website · checked Sep 5, 2026
22
In Touch PharmaceuticalsIndirect evidence
Valparaiso, IN, United StatesHQ checked Sep 5, 202651-20050

“Privately owned long term care pharmacy in 2004, In Touch Pharmaceuticals pioneered the unit dose short-cycle, and our technological innovations, help clients improve performance…”

Source: company website · checked Sep 5, 2026
23
Millennium Pharmacy SystemsIndirect evidence
Oak Brook, IL, United StatesHQ checked Sep 5, 2026501-1,00050

“Millennium replaces frustration, inefficiency, and waste with responsiveness, efficiency, and cost savings.”

Source: company website · checked Sep 5, 2026
24
TalystIndirect evidence
Kirkland, WA, United StatesHQ checked Sep 5, 202651-20049

“Talyst’s purpose is to improve patient safety in all care environments.”

Source: company website · checked Sep 5, 2026
25
Levrx Technology INCStrong evidence
Troy, NY, United StatesHQ checked Sep 5, 202611-5048

“Levrx is a robust software development company that is hyper-focused on transforming how individuals’ shop, save, and manage their prescriptions.”

Source: company website · checked Sep 5, 2026

Showing 25 of 208 prescription compliance software companies based in the United States

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Prescription compliance software companies based in the United States at a glance

As of Sep 5, 2026
11-50Median size (employees)
ColumbusLargest hub · 5 HQs
3,832Contacts with mobile numbers
Sep 5, 2026Data refreshed

Companies by employee count

1-10
78
11-50
77
51-200
31
201-500
12
501-1,000
6
1,001-5,000
3
10001+
1

Verified emails by last verification

0–30
2,873
31–60
182
61–90
2
90–180
4
180+
13

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among prescription compliance software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “prescription compliance software companies”. Matching reads each company's description, not its industry code or its name.
What we exclude
Companies whose own description does not clearly place them among prescription compliance software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 3,074 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

How many prescription compliance software companies are there based in the United States?

RevenueBase identified 208 prescription compliance software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Covermymeds, headquartered in Columbus, tops this list with the largest team on record.

Which city has the most prescription compliance software companies?

Columbus leads with 5 headquartered companies, followed by Houston (5) and Los Angeles (5).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 3,074 verified decision-maker contacts tracked across these 208 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.