Company lists · Data refreshed September 2026
Top 25 Predictive digital twin software companies based in the United States
RevenueBase identified 165 predictive digital twin software companies headquartered in the United States as of September 2026 and tracks 59,980 professional contacts across them, including 28,911 with verified work emails. Houston is the largest hub.
This list covers predictive digital twin software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 27, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest predictive digital twin software companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 21,030 contacts → | ||||
Indirect evidence “Autodesk is changing how the world is designed and made.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 2 | 14,467 contacts → | ||||
Strong evidence “We help organizations of all sizes digitally transform using software, hardware and services from the Siemens Xcelerator business platform.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 3 | 11,702 contacts → | ||||
Strong evidence “Cadence is a market leader in AI and digital twins, pioneering the application of computational software to accelerate innovation in the engineering design of silicon to systems.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 4 | 3,306 contacts → | ||||
Partial evidence “AspenTech is a global software leader helping industries at the forefront of the world’s dual challenge meet the increasing demand for resources from a rapidly growing population…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 5 | 699 contacts → | ||||
Indirect evidence “In an era where the world is rapidly advancing towards a cleaner future through decarbonization, Energy Exemplar’s mission lies in ‘Empowering Transformative Energy Decisions’🪫…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 6 | 633 contacts → | ||||
Partial evidence “MSC Software, part of Cadence's physical systems simulation division, is one of the ten original software companies and a global leader in helping product manufacturers to advance…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 7 | 521 contacts → | ||||
Partial evidence “COMSOL develops mathematical modeling software for driving new breakthroughs in physics and engineering.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 8 | 513 contacts → | ||||
Indirect evidence “At Matterport, we're on a mission to unlock the full potential of properties for our customers.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 9 | 273 contacts → | ||||
Partial evidence “Hawk Ridge Systems helps engineers and manufacturers design and build better products with industry-leading software, 3D printing, 3D scanning, and expert services and training.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 10 | 247 contacts → | ||||
Indirect evidence “CD-adapco is a Siemens business focused on CFD engineering simulation with a unique vision for Multidisciplinary Design eXploration (MDX).” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 11 | 149 contacts → | ||||
Indirect evidence “inmind.ai is an AI innovation powerhouse driving the next frontier of Agentic Transformation across enterprises.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 12 | 148 contacts → | ||||
Indirect evidence “Eudia builds Enterprise Intelligence.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 13 | 145 contacts → | ||||
Indirect evidence “VIAS3D provides integrated engineering solutions using virtual design experience and data analytics in a variety of industries.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 14 | 112 contacts → | ||||
Indirect evidence “Established in Detechtion.AI helps upstream and midstream oil and gas operators, natural gas compression service providers, and energy companies manage complex assets.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 15 | 110 contacts → | ||||
Indirect evidence “Engineering is being outpaced by its own ambition.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 16 | 95 contacts → | ||||
Indirect evidence “Univa was acquired by Altair (Nasdaq: ALTR) in September 2020.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 17 | 92 contacts → | ||||
Partial evidence “Exa, part of SIMULIA a Dassault Systèmes brand, provides simulation and visualization software that predicts the real world performance of products early in the design process.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 18 | 69 contacts → | ||||
Partial evidence “Istari Digital is the agentic AI infrastructure for defense, aerospace, and other industries where failure is not an option.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 19 | 64 contacts → | ||||
Strong evidence “Engineering the digital twin infrastructure for human capital.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 20 | 55 contacts → | ||||
Indirect evidence “Voovio's simulation and productivity tools for industrial field operations save money, lower operational risk and reduce environmental impact.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 21 | 55 contacts → | ||||
Indirect evidence “At MN Engineering Solutions, we help manufacturers unlock smarter ways to design, operate, and optimize.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 22 | 53 contacts → | ||||
Partial evidence “Third Wave Systems develops and sells premier materials-based modeling software and services for machining solutions.” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 23 | 49 contacts → | ||||
Strong evidence “edgeTI helps customers sustain situational awareness and accelerate action with its real-time digital operations software, edgeCore™ that unites multiple software applications and…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 24 | 47 contacts → | ||||
Strong evidence “Designed by industrial automation and digital manufacturing pioneers, TwinThread's digital twin based cloud native Industrial Cloud Platform is purpose-built to help industrial…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
| 25 | 41 contacts → | ||||
Indirect evidence “FS Studio builds product solutions designed to simulate your robotic platform, autonomous devices, IIoT (Industrial Internet of Things) devices, complex systems, autonomous…” Source: RevenueBase Database · checked Sep 27, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: predictive digital twin software companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names predictive digital twin software companies.
- Partial evidence
- Its own public description names part of predictive digital twin software companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name predictive digital twin software companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 165 predictive digital twin software companies based in the United States
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Predictive digital twin software companies based in the United States at a glance
As of Sep 27, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 165 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among predictive digital twin software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “predictive digital twin software companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names predictive digital twin software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among predictive digital twin software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 28,911 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 27, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names predictive digital twin software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many predictive digital twin software companies are there based in the United States?
RevenueBase identified 165 predictive digital twin software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Autodesk, headquartered in San Francisco, tops this list with the largest team on record.
Which city has the most predictive digital twin software companies?
Houston leads with 9 headquartered companies, followed by New York (8) and San Francisco (7).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 28,911 verified decision-maker contacts tracked across these 165 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 27, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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