Company lists · Data refreshed September 2026

Top 25 Patient adherence software companies based in the United States

RevenueBase identified 107 patient adherence software companies headquartered in the United States as of September 2026 and tracks 2,132 professional contacts across them, including 795 with verified work emails and 805 with mobile numbers. Boston is the largest hub.

This list covers patient adherence software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
107Companies
2,132Contacts tracked
795Verified emails
805Mobile numbers
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The 25 largest patient adherence software companies based in the United States

Ranked by team size
Top 25 of 107 patient adherence software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. RevenueBase Smart Search rates how each company's information relates to patient adherence software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceArlington, VA, United StatesHQ checked Sep 5, 2026201-500430 contacts →

Partial evidence

“DrFirst has been transforming medication management for 25 years, helping providers and patients navigate a complex and often fragmented healthcare system.”

Source: RevenueBase Database · checked Sep 5, 2026
2Partial evidenceFranklin, TN, United StatesHQ checked Sep 5, 2026501-1,000198 contacts →

Partial evidence

“AdhereHealth is a healthcare technology solutions leader supporting health plans, self-insured employers, and other risk-bearing entities for medication adherence insights and…”

Source: RevenueBase Database · checked Sep 5, 2026
3Partial evidenceSan Jose, CA, United StatesHQ checked Sep 5, 2026201-500162 contacts →

Partial evidence

“BrightInsight is the patient persistence solution for the world's top pharma and biotech companies.”

Source: RevenueBase Database · checked Sep 5, 2026
4Partial evidenceSummit, NJ, United StatesHQ checked Sep 5, 202651-200157 contacts →

Partial evidence

“Atlantis Health helps pharma and healthcare organizations improve patient experience, outcomes and impact with patient engagement strategies and solutions based on what drives…”

Source: RevenueBase Database · checked Sep 5, 2026
5Indirect evidenceMoline, IL, United StatesHQ checked Sep 5, 2026501-1,000147 contacts →

Indirect evidence

“Our vision is to fix and reimagine healthcare for everyone.”

Source: RevenueBase Database · checked Sep 5, 2026
6Indirect evidenceLos Angeles, CA, United StatesHQ checked Sep 5, 202651-20094 contacts →

Indirect evidence

“Wellth is the daily member relationship platform, proven across millions of members.”

Source: RevenueBase Database · checked Sep 5, 2026
7Partial evidenceThonotosassa, FL, United StatesHQ checked Sep 5, 202611-5089 contacts →

Partial evidence

“Medicine-On-Time, a division of Clarest Health, is a leader in personalized medication adherence solutions, empowering pharmacies and healthcare providers to optimize medication…”

Source: RevenueBase Database · checked Sep 5, 2026
8Partial evidenceBoston, MA, United StatesHQ checked Sep 5, 202651-20085 contacts →

Partial evidence

“Medisafe is the leading enterprise patient engagement platform redefining how pharmaceutical companies support patients across the treatment journey.”

Source: RevenueBase Database · checked Sep 5, 2026
9Partial evidenceMorrisville, NC, United StatesHQ checked Sep 5, 202651-20057 contacts →

Partial evidence

“Spencer Health Solutions is transforming healthcare by moving care delivery to the home through the company’s spencer® medication adherence and engagement platform.”

Source: RevenueBase Database · checked Sep 5, 2026
10Indirect evidenceBrooklandville, MD, United StatesHQ checked Sep 5, 202651-20050 contacts →

Indirect evidence

“Scene Health (formerly emocha Health) is solving the decades-old problem of medication nonadherence by leveraging the power of people, science, and technology.”

Source: RevenueBase Database · checked Sep 5, 2026
11Strong evidenceCarrollton, GA, United StatesHQ checked Sep 5, 202651-20042 contacts →

Strong evidence

“CareTrack’s adherence system enables primary care physicians to monitor critically and chronically ill patient care plan adherence to proactively identify and escalate earlier…”

Source: RevenueBase Database · checked Sep 5, 2026
12Partial evidenceSummit, NJ, United StatesHQ checked Sep 5, 202611-5035 contacts →

Partial evidence

“Founded in 2011, AdhereTech is a privately held digital health company headquartered in Summit, NJ, and is the leading provider and pioneer of real-time medication adherence…”

Source: RevenueBase Database · checked Sep 5, 2026
13Indirect evidenceProspect, KY, United StatesHQ checked Sep 5, 202611-5034 contacts →

Indirect evidence

“The most expensive problem in healthcare isn’t disease.”

Source: RevenueBase Database · checked Sep 5, 2026
14Partial evidenceDallas, United StatesHQ checked Sep 5, 202611-5033 contacts →

Partial evidence

“Pt Pal tracks patients' tasks and enables surveys to be taken easily by the patient.”

Source: RevenueBase Database · checked Sep 5, 2026
15Strong evidenceWest Lafayette, IN, United StatesHQ checked Sep 5, 202611-5019 contacts →

Strong evidence

“Concordance Health Solutions offers products and services to improve patient medication adherence in partnership with pharmacists and other healthcare providers.”

Source: RevenueBase Database · checked Sep 5, 2026
16Partial evidenceNew York, NY, United StatesHQ checked Sep 5, 202611-5016 contacts →

Partial evidence

“MedicaSafe creates innovative technologies for guiding patients through high-stakes outpatient medication therapies.”

Source: RevenueBase Database · checked Sep 5, 2026
17Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 5, 202651-20016 contacts →

Indirect evidence

“CareZone was acquired by Walmart in 2020.] CareZone makes it easy to manage multiple medications and organize health information from your smartphone.”

Source: RevenueBase Database · checked Sep 5, 2026
18Strong evidenceBakersfield, CA, United StatesHQ checked Sep 5, 202611-5016 contacts →

Strong evidence

“SPAC) International has developed innovative software and mHealth applications to keep physicians and patients engaged from the time a script is initiated through the entire…”

Source: RevenueBase Database · checked Sep 5, 2026
19Partial evidenceBloomington, MN, United StatesHQ checked Sep 5, 202611-5015 contacts →

Partial evidence

“Ōmcare is a digital health company that aims to change the way the world cares by extending the reach of caregivers, increasing medication adherence, and improving treatment…”

Source: RevenueBase Database · checked Sep 5, 2026
20Indirect evidenceLeawood, KS, United StatesHQ checked Sep 5, 202611-5012 contacts →

Indirect evidence

“Lifescience Technologies is a mHealth company located at 5251 W.”

Source: RevenueBase Database · checked Sep 5, 2026
21Partial evidenceBurlington, VT, United StatesHQ checked Sep 5, 202611-5010 contacts →

Partial evidence

“Aprexis Health Solutions is the premier company empowering pharmacist and provider- led medication adherence.”

Source: RevenueBase Database · checked Sep 5, 2026
22Partial evidenceChicago, IL, United StatesHQ checked Sep 5, 202611-509 contacts →

Partial evidence

“EveryDose is a digital health company committed to improving medication adherence through best-in-class technology.”

Source: RevenueBase Database · checked Sep 5, 2026
23Indirect evidenceNew York, OK, United StatesHQ checked Sep 5, 202611-509 contacts →

Indirect evidence

“PatchRx is now a part of Custom Health (July 2025).”

Source: RevenueBase Database · checked Sep 5, 2026
24Indirect evidenceNorwalk, CT, United StatesHQ checked Sep 5, 202611-507 contacts →

Indirect evidence

“HealthPrize works with pharma, health plans, employers and health systems to enable people with one or more chronic conditions to take control of their treatment plan, reduce…”

Source: RevenueBase Database · checked Sep 5, 2026
25Partial evidenceWashington, DC, United StatesHQ checked Sep 5, 20261-107 contacts →

Partial evidence

“Welcome to Montuno Software.”

Source: RevenueBase Database · checked Sep 5, 2026

Showing 25 of 107 patient adherence software companies based in the United States

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Patient adherence software companies based in the United States at a glance

As of Sep 5, 2026
37.3%Verified-email coverage
37.8%Mobile-number coverage
19.9Average contacts per company
1-10Median size (employees)
4.7%Largest-city concentration · Boston
Sep 5, 2026Page data refreshed

Companies by employee count

1-10
56
11-50
30
51-200
14
201-500
3
501-1,000
2
1,001-5,000
1
10001+
1

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among patient adherence software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “patient adherence software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names patient adherence software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among patient adherence software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 795 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names patient adherence software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many patient adherence software companies are there based in the United States?

RevenueBase identified 107 patient adherence software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Drfirst, INC, headquartered in Arlington, tops this list with the largest team on record.

Which city has the most patient adherence software companies?

Boston leads with 5 headquartered companies, followed by San Francisco (4) and Atlanta (3).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 795 verified decision-maker contacts tracked across these 107 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.