Company lists · Data refreshed September 2026

Top 25 Patient adherence software companies based in the United States

RevenueBase identified 107 patient adherence software companies headquartered in the United States as of September 2026 and tracks 2,132 professional contacts across them, including 795 with verified work emails and 805 with mobile numbers. Boston is the largest hub.

This list covers patient adherence software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
107Companies
2,132Contacts tracked
795Verified emails
805Mobile numbers
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The 25 largest patient adherence software companies based in the United States

Ranked by team size
Top 25 of 107 patient adherence software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names patient adherence software companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#CompanyHeadquartersEmployeesContacts
1
Drfirst, INCPartial evidence
Arlington, VA, United StatesHQ checked Sep 5, 2026201-500430

“DrFirst has been transforming medication management for 25 years, helping providers and patients navigate a complex and often fragmented healthcare system.”

Source: company website · checked Sep 5, 2026
2
Adherehealth, LLCPartial evidence
Franklin, TN, United StatesHQ checked Sep 5, 2026501-1,000198

“AdhereHealth is a healthcare technology solutions leader supporting health plans, self-insured employers, and other risk-bearing entities for medication adherence insights and…”

Source: company website · checked Sep 5, 2026
3
BrightinsightPartial evidence
San Jose, CA, United StatesHQ checked Sep 5, 2026201-500162

“BrightInsight is the patient persistence solution for the world's top pharma and biotech companies.”

Source: company website · checked Sep 5, 2026
4
Atlantis HealthPartial evidence
Summit, NJ, United StatesHQ checked Sep 5, 202651-200157

“Atlantis Health helps pharma and healthcare organizations improve patient experience, outcomes and impact with patient engagement strategies and solutions based on what drives…”

Source: company website · checked Sep 5, 2026
5
DivvydoseIndirect evidence
Moline, IL, United StatesHQ checked Sep 5, 2026501-1,000147

“Our vision is to fix and reimagine healthcare for everyone.”

Source: company website · checked Sep 5, 2026
6
WellthIndirect evidence
Los Angeles, CA, United StatesHQ checked Sep 5, 202651-20094

“Wellth is the daily member relationship platform, proven across millions of members.”

Source: company website · checked Sep 5, 2026
7
Medicine-On-TimePartial evidence
Thonotosassa, FL, United StatesHQ checked Sep 5, 202611-5089

“Medicine-On-Time, a division of Clarest Health, is a leader in personalized medication adherence solutions, empowering pharmacies and healthcare providers to optimize medication…”

Source: company website · checked Sep 5, 2026
8
MedisafePartial evidence
Boston, MA, United StatesHQ checked Sep 5, 202651-20085

“Medisafe is the leading enterprise patient engagement platform redefining how pharmaceutical companies support patients across the treatment journey.”

Source: company website · checked Sep 5, 2026
9Morrisville, NC, United StatesHQ checked Sep 5, 202651-20057

“Spencer Health Solutions is transforming healthcare by moving care delivery to the home through the company’s spencer® medication adherence and engagement platform.”

Source: company website · checked Sep 5, 2026
10
Scene HealthIndirect evidence
Brooklandville, MD, United StatesHQ checked Sep 5, 202651-20050

“Scene Health (formerly emocha Health) is solving the decades-old problem of medication nonadherence by leveraging the power of people, science, and technology.”

Source: company website · checked Sep 5, 2026
11
Caretrack HealthStrong evidence
Carrollton, GA, United StatesHQ checked Sep 5, 202651-20042

“CareTrack’s adherence system enables primary care physicians to monitor critically and chronically ill patient care plan adherence to proactively identify and escalate earlier…”

Source: company website · checked Sep 5, 2026
12
AdheretechPartial evidence
Summit, NJ, United StatesHQ checked Sep 5, 202611-5035

“Founded in 2011, AdhereTech is a privately held digital health company headquartered in Summit, NJ, and is the leading provider and pioneer of real-time medication adherence…”

Source: company website · checked Sep 5, 2026
13
HealthyrIndirect evidence
Prospect, KY, United StatesHQ checked Sep 5, 202611-5034

“The most expensive problem in healthcare isn’t disease.”

Source: company website · checked Sep 5, 2026
14
PT PALPartial evidence
Dallas, United StatesHQ checked Sep 5, 202611-5033

“Pt Pal tracks patients' tasks and enables surveys to be taken easily by the patient.”

Source: company website · checked Sep 5, 2026
15West Lafayette, IN, United StatesHQ checked Sep 5, 202611-5019

“Concordance Health Solutions offers products and services to improve patient medication adherence in partnership with pharmacists and other healthcare providers.”

Source: company website · checked Sep 5, 2026
16
Medicasafe, INCPartial evidence
New York, NY, United StatesHQ checked Sep 5, 202611-5016

“MedicaSafe creates innovative technologies for guiding patients through high-stakes outpatient medication therapies.”

Source: company website · checked Sep 5, 2026
17
CarezoneIndirect evidence
San Francisco, CA, United StatesHQ checked Sep 5, 202651-20016

“CareZone was acquired by Walmart in 2020.] CareZone makes it easy to manage multiple medications and organize health information from your smartphone.”

Source: company website · checked Sep 5, 2026
18Bakersfield, CA, United StatesHQ checked Sep 5, 202611-5016

“SPAC) International has developed innovative software and mHealth applications to keep physicians and patients engaged from the time a script is initiated through the entire…”

Source: company website · checked Sep 5, 2026
19
ŌmcarePartial evidence
Bloomington, MN, United StatesHQ checked Sep 5, 202611-5015

“Ōmcare is a digital health company that aims to change the way the world cares by extending the reach of caregivers, increasing medication adherence, and improving treatment…”

Source: company website · checked Sep 5, 2026
20
Lifescience TechnologiesIndirect evidence
Leawood, KS, United StatesHQ checked Sep 5, 202611-5012

“Lifescience Technologies is a mHealth company located at 5251 W.”

Source: company website · checked Sep 5, 2026
21
Aprexis Health SolutionsPartial evidence
Burlington, VT, United StatesHQ checked Sep 5, 202611-5010

“Aprexis Health Solutions is the premier company empowering pharmacist and provider- led medication adherence.”

Source: company website · checked Sep 5, 2026
22
EverydosePartial evidence
Chicago, IL, United StatesHQ checked Sep 5, 202611-509

“EveryDose is a digital health company committed to improving medication adherence through best-in-class technology.”

Source: company website · checked Sep 5, 2026
23
PatchrxIndirect evidence
New York, OK, United StatesHQ checked Sep 5, 202611-509

“PatchRx is now a part of Custom Health (July 2025).”

Source: company website · checked Sep 5, 2026
24
HealthprizeIndirect evidence
Norwalk, CT, United StatesHQ checked Sep 5, 202611-507

“HealthPrize works with pharma, health plans, employers and health systems to enable people with one or more chronic conditions to take control of their treatment plan, reduce…”

Source: company website · checked Sep 5, 2026
25Washington, DC, United StatesHQ checked Sep 5, 20261-107

“Welcome to Montuno Software.”

Source: company website · checked Sep 5, 2026

Showing 25 of 107 patient adherence software companies based in the United States

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Patient adherence software companies based in the United States at a glance

As of Sep 5, 2026
1-10Median size (employees)
BostonLargest hub · 5 HQs
805Contacts with mobile numbers
Sep 5, 2026Data refreshed

Companies by employee count

1-10
56
11-50
30
51-200
14
201-500
3
501-1,000
2
1,001-5,000
1
10001+
1

Verified emails by last verification

0–30
736
31–60
44
61–90
1
90–180
0
180+
14

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among patient adherence software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “patient adherence software companies”. Matching reads each company's description, not its industry code or its name.
What we exclude
Companies whose own description does not clearly place them among patient adherence software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 795 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

How many patient adherence software companies are there based in the United States?

RevenueBase identified 107 patient adherence software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Drfirst, INC, headquartered in Arlington, tops this list with the largest team on record.

Which city has the most patient adherence software companies?

Boston leads with 5 headquartered companies, followed by San Francisco (4) and Atlanta (3).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 795 verified decision-maker contacts tracked across these 107 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.