Company lists · Data refreshed September 2026

Top 25 Ophthalmology software companies based in the United States

RevenueBase identified 528 ophthalmology software companies headquartered in the United States as of September 2026 and tracks 18,949 professional contacts across them, including 7,974 with verified work emails and 6,858 with mobile numbers. New York is the largest hub.

This list covers ophthalmology software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 5, 2026 86% judged on-target in blind review
528Companies
18,949Contacts tracked
7,974Verified emails
6,858Mobile numbers
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The 25 largest ophthalmology software companies based in the United States

Ranked by team size
Top 25 of 528 ophthalmology software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. RevenueBase Smart Search rates how each company's information relates to ophthalmology software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceJacksonville, FL, United StatesHQ checked Sep 5, 20265,001-10,0005,005 contacts →

“As a leader in eye health and part of Johnson & Johnson MedTech, we are driven by a bold ambition: Vision Made Possible™- paving the way for a new future of eye health to support…”

Source: company website · checked Sep 5, 2026
2Indirect evidenceAliso Viejo, CA, United StatesHQ checked Sep 5, 20261,001-5,0001,003 contacts →

“At Glaukos, our focus is to develop and lead the global ophthalmic market with novel therapies for the treatment of glaucoma, corneal disorders, and retinal diseases-therapies…”

Source: company website · checked Sep 5, 2026
3Indirect evidenceWaltham, MA, United StatesHQ checked Sep 5, 20261,001-5,000861 contacts →

“At BVI, we are at the forefront of innovation in ophthalmic surgery, delivering cutting-edge solutions that enhance patient care and improve vision outcomes.”

Source: company website · checked Sep 5, 2026
4Partial evidenceKirkwood, MO, United StatesHQ checked Sep 5, 2026201-500564 contacts →

“What began as Clarkson Eyecare in Missouri/Illinois, has now grown to more than 230 Optometry and Ophthalmology practices in 10 states including Missouri, Illinois, Ohio…”

Source: company website · checked Sep 5, 2026
5Indirect evidenceAndover, MA, United StatesHQ checked Sep 5, 2026201-500530 contacts →

“Ora is the world's leading full-service ophthalmic drug and device development firm with offices in the United States, United Kingdom, Australia, and Asia.”

Source: company website · checked Sep 5, 2026
6Indirect evidenceAliso Viejo, CA, United StatesHQ checked Sep 5, 202651-200390 contacts →

“RxSight® is an ophthalmic medical technology corporation headquartered in Aliso Viejo, California that has commercialized the world’s first and only adjustable intraocular lens…”

Source: company website · checked Sep 5, 2026
7Indirect evidenceTempe, AZ, United StatesHQ checked Sep 5, 20261,001-5,000382 contacts →

“American Vision Partners is one of the nation’s largest and fastest-growing eye care physician services organizations.”

Source: company website · checked Sep 5, 2026
8Partial evidenceTampa, FL, United StatesHQ checked Sep 5, 2026201-500303 contacts →

“The only technology partner solely focused on eyecare, Sightview offers ophthalmologists, optometrists, and opticians a single, end-to-end solution that addresses the needs and…”

Source: company website · checked Sep 5, 2026
9Partial evidenceNew Providence, NJ, United StatesHQ checked Sep 5, 20261,001-5,000287 contacts →

“PRISM Vision Group® is the largest vertically-integrated independent ophthalmology administrative services organization (ASO) operating exclusively on the east coast.”

Source: company website · checked Sep 5, 2026
10Indirect evidenceMarietta, GA, United StatesHQ checked Sep 5, 2026201-500249 contacts →

“Originally founded in 1967 by Dr.”

Source: company website · checked Sep 5, 2026
11Indirect evidenceMenlo Park, CA, United StatesHQ checked Sep 5, 2026201-500246 contacts →

“We are reimagining eyecare with transformative technology and an interventional mindset.”

Source: company website · checked Sep 5, 2026
12Indirect evidenceMansfield, MA, United StatesHQ checked Sep 5, 2026201-500234 contacts →

“Hilco Vision is a global eye care company that combines brands including Bruder® Healthcare dry eye products, M&S Technologies® visual acuity systems, OnGuard® prescription safety…”

Source: company website · checked Sep 5, 2026
13Partial evidenceHillsboro, OR, United StatesHQ checked Sep 5, 2026201-500220 contacts →

“How do you keep your optometry and ophthalmology exam lanes moving while managing compliance, costs, cash flow, and staff?”

Source: company website · checked Sep 5, 2026
14Indirect evidenceRancho Cordova, CA, United StatesHQ checked Sep 5, 2026201-500205 contacts →

“Deeply rooted in optometry and backed by VSP®, Eyefinity is the leading provider of practice management and electronic health record solutions, customized for the eye care…”

Source: company website · checked Sep 5, 2026
15Indirect evidenceBloomington, MN, United StatesHQ checked Sep 5, 2026201-500176 contacts →

“Sightpath Medical delivers custom access to advanced ophthalmic equipment and services.”

Source: company website · checked Sep 5, 2026
16Partial evidenceLake Success, NY, United StatesHQ checked Sep 5, 2026n/a166 contacts →

“DigitalOptometrics is a leading digital health platform and software technology company transforming the delivery of comprehensive eye exams.”

Source: company website · checked Sep 5, 2026
17Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 5, 202651-200160 contacts →

“LENZ Therapeutics is a pharmaceutical company developing innovative ophthalmic pharmaceutical products that improve vision.”

Source: company website · checked Sep 5, 2026
18Indirect evidenceThe Colony, TX, United StatesHQ checked Sep 5, 20261,001-5,000143 contacts →

“Nidek offers a wide array of equipment designed for the diagnosis and treatment of retinal diseases, glaucoma, and other vision-impairing afflictions.”

Source: company website · checked Sep 5, 2026
19Partial evidenceRichmond, VA, United StatesHQ checked Sep 5, 2026201-500134 contacts →

“Virginia Eye Institute (VEI) is a comprehensive eye care organization providing a wide range of ophthalmology, optometry, and optical services in 8 locations across Central…”

Source: company website · checked Sep 5, 2026
20Partial evidenceAnnapolis, MD, United StatesHQ checked Sep 5, 202651-200133 contacts →

“RXNT is a Maryland-based ambulatory healthcare software pioneer that empowers medical practices and healthcare organizations to succeed and scale through intuitive, data-backed…”

Source: company website · checked Sep 5, 2026
21Indirect evidenceHickory, NC, United StatesHQ checked Sep 5, 2026201-500127 contacts →

“Graystone Eye was founded in 1969 and now proudly serves patients from six office locations: Hickory, Lenoir, Lincolnton, Boone, North Wilkesboro, and our Retina Center.”

Source: company website · checked Sep 5, 2026
22Indirect evidenceDallas, TX, United StatesHQ checked Sep 5, 202651-200120 contacts →

“We offer speciality-based EHR, Practice Management, & Patient Engagement solutions to help physicians streamline clinical operations, enhance administrative activities, and…”

Source: company website · checked Sep 5, 2026
23Indirect evidenceLombard, IL, United StatesHQ checked Sep 5, 202651-200119 contacts →

“Visionix USA, as part of the global Visionix organization, serves as the exclusive sales, service, and training provider in the United States for Optovue OCT/OCT-A devices…”

Source: company website · checked Sep 5, 2026
24Indirect evidenceRosenberg, United StatesHQ checked Sep 5, 202651-200116 contacts →
Source: company website · checked Sep 5, 2026
25Partial evidenceDallas, TX, United StatesHQ checked Sep 5, 20261,001-5,000116 contacts →

“EyeCare Services Partners (ESP) provides ownership and practice management of ophthalmologic, optometric and ambulatory surgery centers nationwide.”

Source: company website · checked Sep 5, 2026

Showing 25 of 528 ophthalmology software companies based in the United States

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Ophthalmology software companies based in the United States at a glance

As of Sep 5, 2026
42.1%Verified-email coverage
36.2%Mobile-number coverage
35.9Average contacts per company
11-50Median size (employees)
2.3%Largest-city concentration · New York
Sep 5, 2026Page data refreshed

Companies by employee count

1-10
221
11-50
178
51-200
86
201-500
25
501-1,000
7
1,001-5,000
9
5,001-10,000
1
10001+
1

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among ophthalmology software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “ophthalmology software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names ophthalmology software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among ophthalmology software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 7,974 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names ophthalmology software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many ophthalmology software companies are there based in the United States?

RevenueBase identified 528 ophthalmology software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Johnson & Johnson Vision, headquartered in Jacksonville, tops this list with the largest team on record.

Which city has the most ophthalmology software companies?

New York leads with 12 headquartered companies, followed by Miami (10) and San Francisco (8).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 7,974 verified decision-maker contacts tracked across these 528 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.