Company lists · Data refreshed September 2026

Top 25 Neurodegenerative disorder gene therapy companies based in the United States

RevenueBase identified 405 neurodegenerative disorder gene therapy companies headquartered in the United States as of September 2026 and tracks 14,836 professional contacts across them, including 7,612 with verified work emails. Cambridge is the largest hub.

This list covers neurodegenerative disorder gene therapy companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 19, 2026 86% judged on-target in blind review
405Companies
14,836Contacts tracked
7,612Verified emails
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The 25 largest neurodegenerative disorder gene therapy companies based in the United States

Ranked by team size
Top 25 of 405 neurodegenerative disorder gene therapy companies based in the United States, ranked by team size, largest first. Data refreshed Sep 19, 2026. RevenueBase Smart Search rates how each company's information relates to neurodegenerative disorder gene therapy companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceCambridge, MA, United StatesHQ checked Sep 19, 2026501-1,0001,359 contacts →

Partial evidence

“Sarepta Therapeutics, headquartered in Cambridge, Massachusetts, is a global biotechnology company on an urgent mission: engineer precision genetic medicine for rare diseases that…”

Source: RevenueBase Database · checked Sep 19, 2026
2Strong evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 19, 2026501-1,000510 contacts →

Strong evidence

“AskBio Inc, a wholly owned and independently operated subsidiary of Bayer AG, is a fully integrated gene therapy company dedicated to developing life-saving medicines and changing…”

Source: RevenueBase Database · checked Sep 19, 2026
3Partial evidenceCambridge, MA, United StatesHQ checked Sep 19, 2026201-500499 contacts →

Partial evidence

“BlueRock Therapeutics is a clinical stage cell therapy company focused on creating cellular medicines to treat devastating diseases.”

Source: RevenueBase Database · checked Sep 19, 2026
4Strong evidenceColumbus, OH, United StatesHQ checked Sep 19, 2026201-500456 contacts →

Strong evidence

“Forge, a member of Ajinomoto Bio-Pharma Services, is a gene therapy development engine, focused on enabling access to life changing gene therapies and helping bring them from idea…”

Source: RevenueBase Database · checked Sep 19, 2026
5Strong evidenceRockville, MD, United StatesHQ checked Sep 19, 2026201-500393 contacts →

Strong evidence

“REGENXBIO is a leading clinical-stage biotechnology company seeking to improve lives through the curative potential of gene therapy.”

Source: RevenueBase Database · checked Sep 19, 2026
6Strong evidenceCambridge, MA, United StatesHQ checked Sep 19, 2026n/a346 contacts →

Strong evidence

“Sage Therapeutics is a biopharmaceutical company committed to developing novel therapies with the potential to transform the lives of people with debilitating disorders of the…”

Source: RevenueBase Database · checked Sep 19, 2026
7Indirect evidenceSeattle, WA, United StatesHQ checked Sep 19, 2026201-500287 contacts →

Indirect evidence

“Sana Biotechnology is focused on utilizing engineered cells as medicines for patients.”

Source: RevenueBase Database · checked Sep 19, 2026
8Strong evidenceCranbury, NJ, United StatesHQ checked Sep 19, 2026201-500258 contacts →

Strong evidence

“Rocket Pharma (NASDAQ: RCKT) is a fully-integrated, clinical-stage company seeking gene therapy cures.”

Source: RevenueBase Database · checked Sep 19, 2026
9Partial evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-200239 contacts →

Partial evidence

“Headquartered in Boston’s Seaport community, Entrada Therapeutics is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new…”

Source: RevenueBase Database · checked Sep 19, 2026
10Partial evidenceEmeryville, CA, United StatesHQ checked Sep 19, 202651-200236 contacts →

Partial evidence

“4DMT is a leading late-stage biotechnology company advancing durable and disease-targeted therapeutics with potential to transform treatment paradigms and provide unprecedented…”

Source: RevenueBase Database · checked Sep 19, 2026
11Partial evidencePearl River, NY, United StatesHQ checked Sep 19, 2026201-500229 contacts →

Partial evidence

“Acorda Therapeutics is a publicly traded (NASDAQ: ACOR) biotechnology company whose mission is to develop therapies that restore neurological function and improve the lives of…”

Source: RevenueBase Database · checked Sep 19, 2026
12Indirect evidenceMorrisville, NC, United StatesHQ checked Sep 19, 202651-200211 contacts →

Indirect evidence

“Our mission is to revolutionize medicine, with the ultimate goal of eliminating human suffering and enabling people to live without the burden of disease.”

Source: RevenueBase Database · checked Sep 19, 2026
13Partial evidenceLexington, MA, United StatesHQ checked Sep 19, 202651-200208 contacts →

Partial evidence

“Voyager Therapeutics, Inc.(Nasdaq: VYGR) is a biotechnology company dedicated to leveraging the power of human genetics to modify the course of – and ultimately cure –…”

Source: RevenueBase Database · checked Sep 19, 2026
14Partial evidenceCleveland, OH, United StatesHQ checked Sep 19, 2026201-500207 contacts →

Partial evidence

“Abeona Therapeutics Inc.”

Source: RevenueBase Database · checked Sep 19, 2026
15Indirect evidenceBoston, MA, United StatesHQ checked Sep 19, 2026201-500203 contacts →

Indirect evidence

“Praxis Precision Medicines is a fully integrated, leading central nervous system (CNS) precision neuroscience biopharmaceutical company, translating insights from genetic…”

Source: RevenueBase Database · checked Sep 19, 2026
16Partial evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200192 contacts →

Partial evidence

“We are a late-stage clinical biotechnology company with a mission to make degenerative brain disorders history.”

Source: RevenueBase Database · checked Sep 19, 2026
17Partial evidenceBedford, MA, United StatesHQ checked Sep 19, 2026201-500183 contacts →

Partial evidence

“Stoke Therapeutics (Nasdaq: STOK), is a biotechnology company dedicated to restoring protein expression by harnessing the body’s potential with RNA medicine.”

Source: RevenueBase Database · checked Sep 19, 2026
18Partial evidenceSan Diego, CA, United StatesHQ checked Sep 19, 202651-200177 contacts →

Partial evidence

“Neurelis, Inc, is dedicated to innovating life-changing therapeutics that help people with neurological conditions gain greater control over their journeys.”

Source: RevenueBase Database · checked Sep 19, 2026
19Strong evidenceRedwood City, CA, United StatesHQ checked Sep 19, 202651-200177 contacts →

Strong evidence

“Adverum Biotechnologies (NASDAQ: ADVM) is a clinical-stage company that aims to establish gene therapy as a new standard of care for highly prevalent ocular diseases with the…”

Source: RevenueBase Database · checked Sep 19, 2026
20Strong evidenceBoston, MA, United StatesHQ checked Sep 19, 202651-200160 contacts →

Strong evidence

“Solid Biosciences is a precision genetic medicine company focused on advancing a portfolio of gene therapy candidates targeting rare neuromuscular and cardiac diseases, including…”

Source: RevenueBase Database · checked Sep 19, 2026
21Strong evidenceSouth San Francisco, CA, United StatesHQ checked Sep 19, 202651-200155 contacts →

Strong evidence

“Encoded Therapeutics is creating one-time, disease-modifying gene therapies for pediatric central nervous system (CNS) disorders with its cell-selective targeting and regulation…”

Source: RevenueBase Database · checked Sep 19, 2026
22Strong evidenceDallas, TX, United StatesHQ checked Sep 19, 202651-200122 contacts →

Strong evidence

“Taysha Gene Therapies is a clinical-stage biotechnology company focused on advancing adeno-associated virus (AAV)-based gene therapies for severe monogenic diseases of the central…”

Source: RevenueBase Database · checked Sep 19, 2026
23Indirect evidenceMalvern, PA, United StatesHQ checked Sep 19, 202651-200121 contacts →

Indirect evidence

“Ocugen, Inc.”

Source: RevenueBase Database · checked Sep 19, 2026
24Strong evidenceRedwood City, CA, United StatesHQ checked Sep 19, 202651-200116 contacts →

Strong evidence

“Maplight is a biopharmaceutical company discovering and developing novel therapeutics for patients with disorders of the central nervous system (CNS).”

Source: RevenueBase Database · checked Sep 19, 2026
25Strong evidenceCambridge, MA, United StatesHQ checked Sep 19, 202651-200115 contacts →

Strong evidence

“Obsidian Therapeutics is pioneering controllable cell and gene therapies to deliver transformative outcomes for patients with intractable diseases.”

Source: RevenueBase Database · checked Sep 19, 2026

Showing 25 of 405 neurodegenerative disorder gene therapy companies based in the United States

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Neurodegenerative disorder gene therapy companies based in the United States at a glance

As of Sep 19, 2026
51.3%Verified-email coverage
36.6Average contacts per company
11-50Median size (employees)
7.9%Largest-city concentration · Cambridge
Sep 19, 2026Page data refreshed

Companies by employee count

1-10
198
11-50
121
51-200
62
201-500
16
501-1,000
5
1,001-5,000
2
10001+
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 405 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among neurodegenerative disorder gene therapy companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “neurodegenerative disorder gene therapy companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names neurodegenerative disorder gene therapy companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among neurodegenerative disorder gene therapy companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 7,612 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Neurodegenerative disorder gene therapy companies by metro

  • Neurodegenerative disorder gene therapy companies in Cambridge32
  • Neurodegenerative disorder gene therapy companies in Boston29

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names neurodegenerative disorder gene therapy companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many neurodegenerative disorder gene therapy companies are there based in the United States?

RevenueBase identified 405 neurodegenerative disorder gene therapy companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Sarepta Therapeutics, headquartered in Cambridge, tops this list with the largest team on record.

Which city has the most neurodegenerative disorder gene therapy companies?

Cambridge leads with 32 headquartered companies, followed by Boston (29) and San Diego (24).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 7,612 verified decision-maker contacts tracked across these 405 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.