Company lists · Data refreshed September 2026

Top 25 Mrna technology companies based in the United States

RevenueBase identified 132 mrna technology companies headquartered in the United States as of September 2026 and tracks 12,848 professional contacts across them, including 7,883 with verified work emails. Cambridge is the largest hub.

This list covers mrna technology companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 20, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 20, 2026 86% judged on-target in blind review
132Companies
12,848Contacts tracked
7,883Verified emails
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The 25 largest mrna technology companies based in the United States

Ranked by team size
Top 25 of 132 mrna technology companies based in the United States, ranked by team size, largest first. Data refreshed Sep 20, 2026. RevenueBase Smart Search rates how each company's information relates to mrna technology companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Partial evidenceCambridge, MA, United StatesHQ checked Sep 20, 20261,001-5,0006,319 contacts →

Partial evidence

“Moderna is a pioneer and leader in the field of mRNA medicine.”

Source: RevenueBase Database · checked Sep 20, 2026
2Indirect evidenceSomerset, NJ, United StatesHQ checked Sep 20, 20261,001-5,0002,154 contacts →

Indirect evidence

“Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies.”

Source: RevenueBase Database · checked Sep 20, 2026
3Indirect evidenceCarlsbad, CA, United StatesHQ checked Sep 20, 2026501-1,0001,313 contacts →

Indirect evidence

“For three decades, Ionis has invented medicines that bring better futures to people with serious diseases.”

Source: RevenueBase Database · checked Sep 20, 2026
4Partial evidenceSan Diego, CA, United StatesHQ checked Sep 20, 2026201-500331 contacts →

Partial evidence

“TriLink BioTechnologies, a Maravai LifeSciences company, is a global leader in nucleic acid and mRNA solutions.”

Source: RevenueBase Database · checked Sep 20, 2026
5Indirect evidenceSan Diego, CA, United StatesHQ checked Sep 20, 202651-200182 contacts →

Indirect evidence

“Founded in 2013 and based in San Diego, California, Arcturus Therapeutics Holdings Inc.(Nasdaq: ARCT) is a messenger RNA medicines company focused on the development of liver and…”

Source: RevenueBase Database · checked Sep 20, 2026
6Indirect evidenceWatertown, MA, United StatesHQ checked Sep 20, 202651-200167 contacts →

Indirect evidence

“Orna Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, is a biotechnology company reshaping RNA therapeutics.”

Source: RevenueBase Database · checked Sep 20, 2026
7Indirect evidenceRockville, MD, United StatesHQ checked Sep 20, 202651-200115 contacts →

Indirect evidence

“Ascend is gene to GMP partner with deep expertise in advanced therapy development and commercialization.”

Source: RevenueBase Database · checked Sep 20, 2026
8Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 20, 202651-200107 contacts →

Indirect evidence

“Vial is a next-generation pharma company.”

Source: RevenueBase Database · checked Sep 20, 2026
9Indirect evidenceWatertown, MA, United StatesHQ checked Sep 20, 202651-20083 contacts →

Indirect evidence

“Landmark Bio is now Artis BioSolutions.”

Source: RevenueBase Database · checked Sep 20, 2026
10Indirect evidenceSeattle, WA, United StatesHQ checked Sep 20, 202651-20080 contacts →

Indirect evidence

“ShapeTX is pioneering the field of programmable RNA medicines to repair the genetic causes of diseases.”

Source: RevenueBase Database · checked Sep 20, 2026
11Indirect evidenceEmeryville, CA, United StatesHQ checked Sep 20, 202651-20077 contacts →

Indirect evidence

“Nutcracker Therapeutics, Inc.”

Source: RevenueBase Database · checked Sep 20, 2026
12Indirect evidenceCambridge, MA, United StatesHQ checked Sep 20, 202611-5065 contacts →

Indirect evidence

“Alltrna is a clinical-stage biotechnology company unlocking tRNA biology to treat disease.”

Source: RevenueBase Database · checked Sep 20, 2026
13Indirect evidenceDurham, NC, United StatesHQ checked Sep 20, 202651-20058 contacts →

Indirect evidence

“BioSkryb Genomics is a venture-backed organization that is transforming single-cell molecular discovery and analysis.”

Source: RevenueBase Database · checked Sep 20, 2026
14Indirect evidenceCambridge, MA, United StatesHQ checked Sep 20, 202651-20055 contacts →

Indirect evidence

“Orbital Therapeutics is advancing a new generation of RNA medicines designed to reprogram cells in vivo, treating diseases at their source.”

Source: RevenueBase Database · checked Sep 20, 2026
15Indirect evidenceRio Rancho, NM, United StatesHQ checked Sep 20, 202611-5055 contacts →

Indirect evidence

“Nature's Toolbox, Inc.(NTx) is advancing the healthcare industry with their cutting-edge biomanufacturing solutions.”

Source: RevenueBase Database · checked Sep 20, 2026
16Partial evidenceWaltham, MA, United StatesHQ checked Sep 20, 202611-5050 contacts →

Partial evidence

“Orionis Biosciences is a life sciences company pioneering technological innovation in genome-scale drug discovery and tunable molecular design of novel therapeutic drug modalities.”

Source: RevenueBase Database · checked Sep 20, 2026
17Partial evidenceSan Diego, CA, United StatesHQ checked Sep 20, 202611-5049 contacts →

Partial evidence

“Eclipsebio develops first-in-class technologies, analyses, and platforms for the development of tomorrow’s RNA-based and RNA-targeting therapies.”

Source: RevenueBase Database · checked Sep 20, 2026
18Partial evidenceCambridge, MA, United StatesHQ checked Sep 20, 202651-20048 contacts →

Partial evidence

“Omega Therapeutics is a clinical-stage biotechnology company pioneering the first systematic approach of using mRNA as programmable epigenomic medicines.”

Source: RevenueBase Database · checked Sep 20, 2026
19Indirect evidenceIrvine, CA, United StatesHQ checked Sep 20, 202651-20046 contacts →

Indirect evidence

“Craif is a molecular diagnostics company leveraging miRNA and machine learning for early cancer detection.”

Source: RevenueBase Database · checked Sep 20, 2026
20Partial evidenceMadison, WI, United StatesHQ checked Sep 20, 202611-5041 contacts →

Partial evidence

“CELLSCRIPT™ provides products and technologies for making and using RNA for translation in cells for clinical research and therapeutics, including RNA comprising pseudouridine (Ψ)…”

Source: RevenueBase Database · checked Sep 20, 2026
21Indirect evidenceJupiter, FL, United StatesHQ checked Sep 20, 2026n/a38 contacts →

Indirect evidence

“Dyadic International, Inc.(Nasdaq: DYAI)- We are a global biotechnology company focused on further improving and leveraging the patented and proprietary C1 expression system to…”

Source: RevenueBase Database · checked Sep 20, 2026
22Partial evidenceCambridge, MA, United StatesHQ checked Sep 20, 202611-5036 contacts →

Partial evidence

“Pioneering tRNA therapeutics to modulate mRNA function and cure a broad range of genetic diseases.”

Source: RevenueBase Database · checked Sep 20, 2026
23Partial evidenceBurlington, VT, United StatesHQ checked Sep 20, 202651-20033 contacts →

Partial evidence

“Vernal Biosciences is a leading provider of high-purity, scalable mRNA manufacturing solutions, enabling researchers and biotech companies to accelerate the development of…”

Source: RevenueBase Database · checked Sep 20, 2026
24Indirect evidenceTucson, AZ, United StatesHQ checked Sep 20, 202651-20032 contacts →

Indirect evidence

“HTG is accelerating precision medicine from diagnosis to treatment by harnessing the power of transcriptome-wide profiling to drive translational research, clinical diagnostics…”

Source: RevenueBase Database · checked Sep 20, 2026
25Indirect evidenceCambridge, MA, United StatesHQ checked Sep 20, 202611-5031 contacts →

Indirect evidence

“Laronde is pioneering a platform that offers a completely novel way of modulating human biology.”

Source: RevenueBase Database · checked Sep 20, 2026

Showing 25 of 132 mrna technology companies based in the United States

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Mrna technology companies based in the United States at a glance

As of Sep 20, 2026
61.4%Verified-email coverage
97.3Average contacts per company
11-50Median size (employees)
18.2%Largest-city concentration · Cambridge
Sep 20, 2026Page data refreshed

Companies by employee count

1-10
60
11-50
43
51-200
19
201-500
6
501-1,000
1
1,001-5,000
3

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 132 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among mrna technology companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “mrna technology companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names mrna technology companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among mrna technology companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 7,883 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names mrna technology companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many mrna technology companies are there based in the United States?

RevenueBase identified 132 mrna technology companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Moderna, headquartered in Cambridge, tops this list with the largest team on record.

Which city has the most mrna technology companies?

Cambridge leads with 24 headquartered companies, followed by San Diego (11) and Boston (9).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 7,883 verified decision-maker contacts tracked across these 132 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.