Company lists · Data refreshed September 2026

Top 25 Mission-driven venture capital companies based in the United States

Name: Mission-driven venture capital companies based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 5, 2026 2,870 companies tracked

RevenueBase identified 2,870 mission-driven venture capital companies headquartered in the United States as of September 2026 and tracks 38,585 professional contacts across them, including 10,289 with verified work emails and 12,925 with mobile numbers. New York is the largest hub.

This list covers mission-driven venture capital companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review

2,870Companies

38,585Contacts tracked

10,289Verified emails

12,925Mobile numbers

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The 25 largest mission-driven venture capital companies based in the United States

Ranked by team size

Top 25 of 2,870 mission-driven venture capital companies based in the United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names mission-driven venture capital companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#	Company	Headquarters	Employees	Contacts
1	Y CombinatorIndirect evidence	San Francisco, CA, United StatesHQ checked Sep 5, 2026	n/a	3,283
	“Y Combinator is the leading startup accelerator for entrepreneurs.” Source: company website · checked Sep 5, 2026
2	ACCELStrong evidence	Palo Alto, CA, United StatesHQ checked Sep 5, 2026	n/a	981
	“Accel is a global venture capital firm that is the first partner to exceptional teams everywhere, from inception through all phases of private company growth.” Source: company website · checked Sep 5, 2026
3	Andreessen HorowitzStrong evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	201-500	932
	“Founded in 2009 by Marc Andreessen and Ben Horowitz, Andreessen Horowitz (known as "a16z") is a venture capital firm that backs bold entrepreneurs building the future through…” Source: company website · checked Sep 5, 2026
4	Hustle FundStrong evidence	San Francisco, CA, United StatesHQ checked Sep 5, 2026	n/a	711
	“Hustle Fund is a venture capital firm investing in hilariously-early pre-seed founders.” Source: company website · checked Sep 5, 2026
5	Lvlup VenturesStrong evidence	New York, NY, United StatesHQ checked Sep 5, 2026	1,001-5,000	610
	“LvlUp Ventures is a global venture capital firm investing in and accelerating early-stage & late-stage startups.” Source: company website · checked Sep 5, 2026
6	Primary Venture PartnersIndirect evidence	New York, NY, United StatesHQ checked Sep 5, 2026	51-200	545
	“Primary is the world's largest early stage VC firm, with a billion in assets under management and 50 full time employees.” Source: company website · checked Sep 5, 2026
7	Alumni VenturesPartial evidence	Manchester, NH, United StatesHQ checked Sep 5, 2026	51-200	411
	“Founded in 2014, we’re America’s largest venture firm for individual investors and VC investing partner to over individuals and institutions.” Source: company website · checked Sep 5, 2026
8	Bessemer Venture PartnersPartial evidence	San Francisco, CA, United StatesHQ checked Sep 5, 2026	201-500	402
	“Bessemer Venture Partners helps entrepreneurs lay strong foundations from inception to build long-standing companies.” Source: company website · checked Sep 5, 2026
9	Sequoia CapitalIndirect evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	51-200	388
	“Sequoia helps daring founders build legendary companies from idea to IPO and beyond.” Source: company website · checked Sep 5, 2026
10	Alchemist AcceleratorPartial evidence	San Francisco, CA, United StatesHQ checked Sep 5, 2026	n/a	321
	“The Alchemist Accelerator is a venture-backed initiative focused on accelerating the development of seed-stage ventures that monetize from enterprises (not consumers).” Source: company website · checked Sep 5, 2026
11	UnreasonableIndirect evidence	Boulder, CO, United StatesHQ checked Sep 5, 2026	n/a	279
	“We are an international company that supports a Fellowship for growth-stage entrepreneurs, channels exclusive deal-flow to investors, and partners with institutions to discover…” Source: company website · checked Sep 5, 2026
12	NEW Enterprise Associates NEAStrong evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	51-200	277
	“New Enterprise Associates, Inc.(NEA) is a global venture capital firm focused on helping entrepreneurs build transformational businesses across multiple stages, sectors and…” Source: company website · checked Sep 5, 2026
13	GV Google VenturesIndirect evidence	San Francisco Bay, MA, United StatesHQ checked Sep 5, 2026	51-200	276
	“GV supports innovative founders across multiple stages and sectors, from artificial intelligence and life sciences to consumer platforms, enterprise software, and frontier…” Source: company website · checked Sep 5, 2026
14	Village CapitalPartial evidence	Washington, DC, United StatesHQ checked Sep 5, 2026	n/a	232
	“Village Capital is reinventing the system to back the entrepreneurs of the future.” Source: company website · checked Sep 5, 2026
15	NEOIndirect evidence	San Francisco, CA, United StatesHQ checked Sep 5, 2026	n/a	221
	“Neo is a diverse mentorship community, startup accelerator, and VC fund.” Source: company website · checked Sep 5, 2026
16	Highland Capital PartnersStrong evidence	Cambridge, MA, United StatesHQ checked Sep 5, 2026	n/a	213
	“Founded in 1987, Highland Capital Partners is a venture capital firm focused on putting the entrepreneur first.” Source: company website · checked Sep 5, 2026
17	Kleiner PerkinsIndirect evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	n/a	205
	“For five decades, Kleiner Perkins has partnered with intrepid founders to build iconic companies that made history.” Source: company website · checked Sep 5, 2026
18	DFJStrong evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	51-200	205
	“DFJ is a venture capital firm that partners with extraordinary entrepreneurs who are changing the world.” Source: company website · checked Sep 5, 2026
19	Goahead VenturesStrong evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	n/a	204
	“GoAhead Ventures is a Venture Capital fund based in Silicon Valley managing over $250M in AUM.” Source: company website · checked Sep 5, 2026
20	First Round CapitalStrong evidence	San Francisco, PA, United StatesHQ checked Sep 5, 2026	n/a	199
	“First Round is a venture capital firm that works with founders exclusively at the earliest stages of company building, often when all they have is an “imagine if.” We fill in…” Source: company website · checked Sep 5, 2026
21	VC LABStrong evidence	Palo Alto, CA, United StatesHQ checked Sep 5, 2026	n/a	197
	“VC Lab is the world's leading venture capital accelerator.” Source: company website · checked Sep 5, 2026
22	Khosla VenturesPartial evidence	Menlo Park, CA, United StatesHQ checked Sep 5, 2026	51-200	193
	“Khosla Ventures invests in companies that are bold, early and impactful.” Source: company website · checked Sep 5, 2026
23	WeinvestPartial evidence	New York, NY, United StatesHQ checked Sep 5, 2026	501-1,000	186
	“WeInvest is a Next Generation Venture Builder that creates Early-Stage VC Funds based on a proprietary methodology to launch startups per year by leveraging a global ecosystem of…” Source: company website · checked Sep 5, 2026
24	Persist VenturesStrong evidence	Los Angeles, CA, United StatesHQ checked Sep 5, 2026	201-500	176
	“Persist Ventures is a venture studio with a mission to accelerate innovation and altruism globally.” Source: company website · checked Sep 5, 2026
25	EclipseIndirect evidence	Palo Alto, CA, United StatesHQ checked Sep 5, 2026	n/a	171
	“Eclipse invests in entrepreneurs building the next generation of companies in the physical economy, the industries that shape resilience, competitiveness, and security.” Source: company website · checked Sep 5, 2026

Showing 25 of 2,870 mission-driven venture capital companies based in the United States

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Mission-driven venture capital companies based in the United States at a glance

As of Sep 5, 2026

1-10Median size (employees)

New YorkLargest hub · 345 HQs

12,925Contacts with mobile numbers

Sep 5, 2026Data refreshed

Companies by employee count

1-10

2,235

11-50

534

51-200

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Verified emails by last verification

0–30

9,567

31–60

650

61–90

90–180

180+

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among mission-driven venture capital companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “mission-driven venture capital companies”. Matching reads each company's description, not its industry code or its name.
What we exclude: Companies whose own description does not clearly place them among mission-driven venture capital companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 10,289 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Mission-driven venture capital companies by metro

Frequently asked

How many mission-driven venture capital companies are there based in the United States?

RevenueBase identified 2,870 mission-driven venture capital companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Y Combinator, headquartered in San Francisco, tops this list with the largest team on record.

Which city has the most mission-driven venture capital companies?

New York leads with 345 headquartered companies, followed by San Francisco (332) and Los Angeles (139).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 10,289 verified decision-maker contacts tracked across these 2,870 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.