Company lists · Data refreshed October 2026

Top 25 Metabolic disease biotech companies based in the United States

RevenueBase identified 361 company matches for metabolic disease biotech companies associated with the United States as of October 2026 and tracks 124,201 professional contacts across them, including 56,961 with verified work emails. San Diego is the largest hub.

This list covers company matches for metabolic disease biotech companies associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed October 18, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Oct 18, 2026 How this list was built
361Companies
124,201Contacts tracked
56,961Verified emails
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The 25 largest metabolic disease biotech companies based in the United States

Ranked by team size
Top 25 of 361 company matches for metabolic disease biotech companies based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Oct 18, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchThousand Oaks, CA, United StatesHQ recorded Oct 18, 202610001+35,725 contacts →

Exact match

“Amgen harnesses the best of biology and technology to fight the world’s toughest diseases, and make people’s lives easier, fuller and longer.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
2Exact matchSouth San Francisco, CA, United StatesHQ recorded Oct 18, 202610001+17,827 contacts →

Exact match

“About Genentech We're passionate about finding solutions for people facing the world's most difficult-to-treat conditions.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
3Exact matchTarrytown, NY, United StatesHQ recorded Oct 18, 202610001+16,852 contacts →

Exact match

“At Regeneron we believe that when the right idea finds the right team, powerful change is possible.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
4Exact matchCambridge, MA, United StatesHQ recorded Oct 18, 20265,001-10,00011,060 contacts →

Exact match

“Founded in 1978, Biogen is a leading biotechnology company that pioneers innovative science to deliver new medicines to transform patients’ lives and to create value for…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
5Exact matchBoston, MA, United StatesHQ recorded Oct 18, 20265,001-10,0008,680 contacts →

Exact match

“Vertex is a global biotechnology company that invests in scientific innovation to create transformative medicines for people with serious diseases and has made significant…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
6Exact matchBoston, MA, United StatesHQ recorded Oct 18, 20261,001-5,0006,267 contacts →

Exact match

“Alexion, AstraZeneca Rare Disease is focused on pioneering new possibilities for the rare disease community.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
7Exact matchSan Rafael, CA, United StatesHQ recorded Oct 18, 20261,001-5,0004,093 contacts →

Exact match

“Founded in 1997, BioMarin is a global biotechnology company dedicated to transforming lives through genetic discovery.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
8Exact matchSomerset, NJ, United StatesHQ recorded Oct 18, 20261,001-5,0002,220 contacts →

Exact match

“Legend Biotech is a global, commercial-stage biotechnology company developing and manufacturing novel therapies.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
9Exact matchIrving, TX, United StatesHQ recorded Oct 18, 20261,001-5,0001,681 contacts →

Exact match

“Caris Life Sciences® (Caris) is the leading next-generation TechBio company and precision medicine pioneer that is actively developing and delivering innovative solutions to…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
10Exact matchBridgewater Township, NJ, United StatesHQ recorded Oct 18, 20261,001-5,0001,656 contacts →

Exact match

“Insmed is a people-rst global biopharmaceutical company striving to deliver rst- and best-in-class therapies to transform the lives of patients facing serious diseases.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
11Exact matchNovato, CA, United StatesHQ recorded Oct 18, 20261,001-5,0001,579 contacts →

Exact match

“Leading with purpose.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
12Exact matchConshohocken, PA, United StatesHQ recorded Oct 18, 2026501-1,0001,086 contacts →

Exact match

“Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), formerly known as nonalcoholic…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
13Exact matchPalo Alto, CA, United StatesHQ recorded Oct 18, 2026501-1,000979 contacts →

Exact match

“We exist to bring transformative medicines to people living with genetic conditions.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
14Exact matchDenver, CO, United StatesHQ recorded Oct 18, 20261,001-5,000893 contacts →

Exact match

“Virta Health is on a mission to reverse metabolic disease in one billion people, and we’re already proving it’s possible.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
15Exact matchPrinceton, NJ, United StatesHQ recorded Oct 18, 2026501-1,000739 contacts →

Exact match

“Kyowa Kirin is a global specialty pharmaceutical company that applies state-of-the-art biotechnologies to discover and deliver novel medicines.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
16Exact matchLincolnshire, IL, United StatesHQ recorded Oct 18, 202610001+639 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
17Exact matchWashington, DC, United StatesHQ recorded Oct 18, 2026201-500622 contacts →

Exact match

“Vanda is a leading global biopharmaceutical company focused on the development and commercialization of innovative therapies to address high unmet medical needs and improve the…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
18Exact matchChicago, IL, United StatesHQ recorded Oct 18, 2026201-500542 contacts →

Exact match

“We're a growth-oriented biopharmaceutical company improving patient lives by developing and commercializing advanced products across a range of therapies.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
19Exact matchSan Diego, CA, United StatesHQ recorded Oct 18, 20261,001-5,000535 contacts →

Exact match

“Amylin Pharmaceuticals, a wholly owned subsidiary of Bristol- Myers Squibb, is an exceptional company of extraordinary people.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
20Exact matchSan Diego, CA, United StatesHQ recorded Oct 18, 2026201-500518 contacts →

Exact match

“Our mission is to identify, develop and deliver life-changing therapies to people living with rare disease.#InRareForLife Community Guidelines…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
21Exact matchLexington, MA, United StatesHQ recorded Oct 18, 2026201-500427 contacts →

Exact match

“Kiniksa is a biopharmaceutical company dedicated to improving the lives of patients suffering from debilitating diseases by discovering, acquiring, developing, and commercializing…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
22Exact matchFoster City, CA, United StatesHQ recorded Oct 18, 2026201-500416 contacts →

Exact match

“Mirum Pharmaceuticals is a leading rare disease company with a global footprint of approved products and a broad pipeline of investigational medicines.”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
23Exact matchAnn Arbor, MI, United StatesHQ recorded Oct 18, 2026201-500336 contacts →

Exact match

Recorded description not available.

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
24Exact matchWaltham, MA, United StatesHQ recorded Oct 18, 2026201-500335 contacts →

Exact match

“Sobi is an international specialty healthcare company dedicated to developing treatments and extensive patient support networks for people with rare and difficult to treat…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase
25Exact matchMiami, FL, United StatesHQ recorded Oct 18, 2026201-500330 contacts →

Exact match

“Summit Mission Statement: To build a viable, long-lasting health care organization that assumes full responsibility for designing, developing, trial execution and enrollment…”

Recorded in the RevenueBase company graph · Oct 18, 2026 · View company records in RevenueBase

Showing 25 of 361 metabolic disease biotech companies based in the United States

See the full list, filter by size, metro and specialty, and access 56,961 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Metabolic disease biotech companies based in the United States at a glance

As of Oct 18, 2026
45.9%Verified-email coverage
344.0Average contacts per company
11-50Median size (employees)
5.3%Largest-city concentration · San Diego
Oct 18, 2026Page data refreshed

Companies by employee count

1-10
151
11-50
111
51-200
58
201-500
19
501-1,000
5
1,001-5,000
10
5,001-10,000
2
10001+
4

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 361 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “metabolic disease biotech companies” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 56,961 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on October 18, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “metabolic disease biotech companies”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many metabolic disease biotech companies are there based in the United States?

RevenueBase identified 361 company matches for metabolic disease biotech companies associated with the United States as of October 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

AMGEN tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most metabolic disease biotech companies?

San Diego leads with 19 company records, followed by Cambridge (18) and Boston (17).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 56,961 professional contacts with verified work emails tracked across these 361 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on October 18, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.