Company lists · Data refreshed September 2026

Top 25 Medtech venture capital companies based in Chicago, United States

Name: Medtech venture capital companies based in Chicago, United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 5, 2026 53 companies tracked

RevenueBase identified 53 medtech venture capital companies headquartered in Chicago, United States as of September 2026 and tracks 503 professional contacts across them, including 200 with verified work emails. New York is the largest hub.

This list covers medtech venture capital companies headquartered in Chicago, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 5, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 5, 2026 86% judged on-target in blind review

53Companies

503Contacts tracked

200Verified emails

Unlock all 53 companies Free signup · no credit card · 500 free credits

The 25 largest medtech venture capital companies based in Chicago, United States

Ranked by team size

Top 25 of 53 medtech venture capital companies based in Chicago, United States, ranked by team size, largest first. Data refreshed Sep 5, 2026. Evidence rates how directly each company's own description names medtech venture capital companies: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#	Company	Headquarters	Employees	Contacts
1	Portal InnovationsStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	11-50	67
	“Portal Innovations is a premier venture development engine that bridges scientific ideation in life sciences, medtech, and bioinformatics through commercial proof of concept by…” Source: company website · checked Sep 5, 2026
2	Arch Venture PartnersPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	11-50	62
	“Early stage venture firm focused on life science discoveries to prevent, detect and cure disease.” Source: company website · checked Sep 5, 2026
3	HPAIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	51-200	56
	“HPA is a leading early-stage investor.” Source: company website · checked Sep 5, 2026
4	OCA VenturesStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	n/a	38
	“We're a hands-on, collaborative, and entrepreneur friendly early stage venture capital firm.” Source: company website · checked Sep 5, 2026
5	Abundant Venture PartnersPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	201-500	31
	“Abundant Venture Partners was founded on the belief that healthcare’s most important challenges are too complex for any organization to solve alone.” Source: company website · checked Sep 5, 2026
6	ValtruisIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	28
	“Valtruis invests in, builds, and partners with companies that challenge the healthcare industry’s status quo and revolutionize the way care is accessed, delivered, experienced…” Source: company website · checked Sep 5, 2026
7	2flo VenturesStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	23
	“2Flo Ventures is a startup studio and venture capital firm dedicated to accelerating impactful innovation in healthcare.” Source: company website · checked Sep 5, 2026
8	7wire VenturesPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	16
	“7wire Ventures is an early stage, healthcare venture fund.” Source: company website · checked Sep 5, 2026
9	Corazon CapitalStrong evidence	Chicago, United StatesHQ checked Sep 5, 2026	1-10	16
	“Born out of a love for building startups and a passion for backing entrepreneurs with heart, Corazon Capital (Spanish for “heart”), a leading Chicago-based venture fund, brings a…” Source: company website · checked Sep 5, 2026
10	LongjumpPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	15
	“LongJump is a first-check venture fund, based in Chicago, designed to invest in the next generation of founders.” Source: company website · checked Sep 5, 2026
11	Vcapital ManagementIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	10
	“With an in-depth focus on research and exceptional due diligence plus a 30-year track record, VCapital Management Co.” Source: company website · checked Sep 5, 2026
12	OMX VenturesStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	10
	“OMX Ventures is a venture capital firm focused on investing in a new era of bioengineering and its application for better tools, medicines, foods, industrial products, and more.” Source: company website · checked Sep 5, 2026
13	Tensility Venture PartnersIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	9
	“We seed and grow companies that will revolutionize business by delivering the promise of AI to the enterprise.” Source: company website · checked Sep 5, 2026
14	Distributed VenturesPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	8
	“Distributed Ventures backs bold founders innovating at the frontier of risk.” Source: company website · checked Sep 5, 2026
15	Sandalphon CapitalIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	8
	“Sandalphon leads, co-leads or meaningfully participates in Pre-Seed and Seed stage rounds for B2B healthtech startups Primary industries of interest: HealthTech Tech-Enabled…” Source: company website · checked Sep 5, 2026
16	Pace Healthcare CapitalStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	7
	“PACE Healthcare Capital is an early-stage venture firm investing between the coasts to accelerate digital health and healthcare technology companies that improve outcomes, expand…” Source: company website · checked Sep 5, 2026
17	Propellant VenturesStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	6
	“Propellant Ventures is Seed stage venture capital fund that invests in the growth of Chicago and the greater Midwest across a broad range of powerful, diverse, and leading-edge…” Source: company website · checked Sep 5, 2026
18	Promus VenturesStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	4
	“An experienced and globally focused venture capital company, we are split between the US and Europe.” Source: company website · checked Sep 5, 2026
19	Ranch Ventures Fund I LLCPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	4
	“Ranch Ventures Fund I LLC is an investment banking company based out of 1050 STATE ST, Chicago, Illinois, United States.” Source: company website · checked Sep 5, 2026
20	Pathway BioventuresIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	3
	“Pathway Bioventures is an early-stage life sciences fund for next-generation therapeutics, medical device, and diagnostics companies.” Source: company website · checked Sep 5, 2026
21	GEN 1 CapitalIndirect evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	3
	Source: company website · checked Sep 5, 2026
22	Knowality, LLCPartial evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	2
	“Venture services firm specializing in the acceleration of market adoption for healthcare startups.” Source: company website · checked Sep 5, 2026
23	Kleinmuntz Associates LLCStrong evidence	Chicago, IL, United StatesHQ checked Sep 5, 2026	1-10	2
	“Founded in 2013, Kleinmuntz Associates is a closely-held venture capital firm based in Chicago.” Source: company website · checked Sep 5, 2026
24	Genius GuildStrong evidence	Chicago, United StatesHQ checked Sep 5, 2026	1-10	2
	“Genius Guild, a Chicago-based venture capital firm building a new kind of venture platform focused on creating a world where everyone gets alpha-Investors, Founders, and…” Source: company website · checked Sep 5, 2026
25	K4 Capital GroupPartial evidence	Chicago, United StatesHQ checked Sep 5, 2026	1-10	1
	“At K4 Capital we focus on investing in what we know.” Source: company website · checked Sep 5, 2026

Showing 25 of 53 medtech venture capital companies based in Chicago, United States

See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 200 reachable decision-makers.

Free signup · no credit card

See all 53 companies

Medtech venture capital companies based in Chicago, United States at a glance

As of Sep 5, 2026

1-10Median size (employees)

New YorkLargest hub · 182 HQs

Contacts with mobile numbers

Sep 5, 2026Data refreshed

Companies by employee count

1-10

11-50

51-200

201-500

Email recency for this list is measured across the whole United States list rather than this city, so it is reported there. Company counts and contact totals on this page are exact for Chicago, over 53 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among medtech venture capital companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in Chicago, United States whose own description of what they do matches “medtech venture capital companies”. Matching reads each company's description, not its industry code or its name.
What we exclude: Companies whose own description does not clearly place them among medtech venture capital companies, and records with no verified work email. Companies headquartered outside Chicago are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 200 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 5, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Medtech venture capital companies by metro in the United States

Medtech venture capital companies in New York182
Medtech venture capital companies in San Francisco150
Medtech venture capital companies in Boston74
Medtech venture capital companies in Palo Alto56
Medtech venture capital companies in Chicago53
Medtech venture capital companies in Menlo Park45
Medtech venture capital companies in Los Angeles37
Medtech venture capital companies in Austin33
Medtech venture capital companies in Cambridge31
Medtech venture capital companies in San Diego31
Medtech venture capital companies in Houston25

Frequently asked

How many medtech venture capital companies are there based in Chicago, United States?

RevenueBase identified 53 medtech venture capital companies headquartered in Chicago, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Portal Innovations, headquartered in Chicago, tops this list with the largest team on record.

Which city has the most medtech venture capital companies?

New York leads with 182 headquartered companies, followed by San Francisco (150) and Boston (74).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 200 verified decision-maker contacts tracked across these 53 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 5, 2026.

Ready to reach these companies? Verified emails and direct dials for all 53 medtech venture capital companies based in Chicago, United States. Start with a free account, no credit card.

Get the full list

Related lists

Medtech venture capital companies by geography

Browse the directory

Browse: Companies home · Medtech venture capital companies in United States · All United States lists · All Medtech venture capital companies lists · New lists

About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.