Company lists · Data refreshed September 2026

Top 25 Life sciences venture capital firms based in San Francisco, United States

Name: Life sciences venture capital firms based in San Francisco, United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 14, 2026 170 companies tracked

RevenueBase identified 170 life sciences venture capital firms headquartered in San Francisco, United States as of September 2026 and tracks 1,998 professional contacts across them, including 713 with verified work emails. Across the United States, New York is the largest hub for this category (216 companies); San Francisco follows with 170.

This list covers life sciences venture capital firms headquartered in San Francisco, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 14, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 14, 2026 86% judged on-target in blind review

170Companies

1,998Contacts tracked

713Verified emails

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The 25 largest life sciences venture capital firms based in San Francisco, United States

Ranked by team size

Top 25 of 170 life sciences venture capital firms based in San Francisco, United States, ranked by team size, largest first. Data refreshed Sep 14, 2026. RevenueBase Smart Search rates how each company's information relates to life sciences venture capital firms: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	M12, Microsoft's Venture Fund	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	139 contacts →
	Strong evidence “M12 is Microsoft’s corporate venture capital fund.” Source: RevenueBase Database · checked Sep 14, 2026
2	Contrary	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	136 contacts →
	Indirect evidence “Contrary is a talent and research-driven investment firm.” Source: RevenueBase Database · checked Sep 14, 2026
3	Canaan	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	104 contacts →
	Strong evidence “Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas.” Source: RevenueBase Database · checked Sep 14, 2026
4	WI Harper Group	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	100 contacts →
	Strong evidence “WI Harper Group is a pioneering venture capital firm with over three decades of experience investing in transformative companies that shape the future.” Source: RevenueBase Database · checked Sep 14, 2026
5	Versant Ventures	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	61 contacts →
	Partial evidence “Versant Ventures is a leading healthcare investment firm committed to helping exceptional entrepreneurs build the next generation of great companies.” Source: RevenueBase Database · checked Sep 14, 2026
6	Blumberg Capital	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	49 contacts →
	Strong evidence “Blumberg Capital is an early and growth stage venture capital firm that partners with visionary entrepreneurs to build successful technology companies that empower individuals…” Source: RevenueBase Database · checked Sep 14, 2026
7	Cota Capital	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	48 contacts →
	Partial evidence “Cota Capital is an early-stage investment firm that builds and invests in technology companies addressing “Net New” challenges in the enterprise.” Source: RevenueBase Database · checked Sep 14, 2026
8	Crosslink Capital	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	47 contacts →
	Strong evidence “Crosslink, founded in 1989, is a premier early-stage venture capital firm with over $4.2B in assets.” Source: RevenueBase Database · checked Sep 14, 2026
9	Sosv SF & NY FKA Indiebio	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	n/a	45 contacts →
	Indirect evidence “IndieBio is now known as SOSV NY and SOSV SF.” Source: RevenueBase Database · checked Sep 14, 2026
10	Emergence Capital	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	43 contacts →
	Partial evidence “Emergence Capital invests in people who change the way the world works.” Source: RevenueBase Database · checked Sep 14, 2026
11	5am Ventures	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	43 contacts →
	Strong evidence “5AM was founded in 2002 and pursues investments in advanced life science innovations, and seeks to be diversified across the biopharmaceutical therapeutics, and platform…” Source: RevenueBase Database · checked Sep 14, 2026
12	Spark Capital	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	40 contacts →
	Partial evidence “We are Spark Capital, investors in products we love by creators we admire, including Affirm, Anthropic, Carta, Cruise, Discord, Oculus, Plaid, Postmates, Slack, Twitter, and…” Source: RevenueBase Database · checked Sep 14, 2026
13	Robust	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	n/a	36 contacts →
	Strong evidence “Robust is an early-stage, industry-agnostic venture capital firm that invests globally.” Source: RevenueBase Database · checked Sep 14, 2026
14	Define Ventures	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	29 contacts →
	Partial evidence “Define Ventures is one of the largest funds exclusively focused on early-stage digital health companies with $800 million in assets under management.” Source: RevenueBase Database · checked Sep 14, 2026
15	Ridge Ventures	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	28 contacts →
	Strong evidence “Founded in 2007, Ridge Ventures is an early stage venture capital fund investing in experienced founders redefining how the world interacts with software.” Source: RevenueBase Database · checked Sep 14, 2026
16	Altair Capital	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	27 contacts →
	Strong evidence “AltaIR Capital is an international early-stage venture investment company.” Source: RevenueBase Database · checked Sep 14, 2026
17	Yosemite	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	26 contacts →
	Partial evidence “Yosemite is an oncology-focused venture fund investing in biotech and healthcare innovations to make cancer non-lethal.” Source: RevenueBase Database · checked Sep 14, 2026
18	Marque Ventures	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	26 contacts →
	Partial evidence “At Marque Ventures, we invest in entrepreneurs building the future of American defense, manufacturing, and deep tech innovation by holistically supporting portfolio companies with…” Source: RevenueBase Database · checked Sep 14, 2026
19	The Column Group	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	25 contacts →
	Strong evidence “The Column Group (TCG) is a science-driven venture capital firm that makes significant financial and operational commitments to build early stage drug discovery companies based on…” Source: RevenueBase Database · checked Sep 14, 2026
20	Commerce Ventures	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	19 contacts →
	Strong evidence “Commerce Ventures is an early stage venture capital firm focused on investing and empowering the next generation of technology innovators in the retail and financial services…” Source: RevenueBase Database · checked Sep 14, 2026
21	BEE Partners	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	19 contacts →
	Indirect evidence “At Bee Partners, we passionately believe today’s decades-long supercycle of AI-enabled machines will transform our world via software, hardware, and biology.” Source: RevenueBase Database · checked Sep 14, 2026
22	RPV	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	19 contacts →
	Partial evidence “rpv is a fully deployed DeepTech Venture fund focused on early stage, scientifically intensive ventures.” Source: RevenueBase Database · checked Sep 14, 2026
23	Illumina Ventures	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	18 contacts →
	Partial evidence “Illumina Ventures is an independently managed firm focused on early-stage companies that are pioneering new applications of genomics and enabling precision medicine.” Source: RevenueBase Database · checked Sep 14, 2026
24	Greatpoint Ventures	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	11-50	18 contacts →
	Strong evidence “GreatPoint Ventures is an early-stage venture capital firm founded by entrepreneurs and operators who've built companies cumulatively worth $300 billion.” Source: RevenueBase Database · checked Sep 14, 2026
25	Abstract	Strong evidence	San Francisco, CA, United StatesHQ checked Sep 14, 2026	1-10	16 contacts →
	Strong evidence “Abstract is a venture capital firm based in San Francisco with $1.5 billion in assets under management.” Source: RevenueBase Database · checked Sep 14, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: life sciences venture capital firms. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names life sciences venture capital firms.
Partial evidence: Its own public description names part of life sciences venture capital firms, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name life sciences venture capital firms. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 170 life sciences venture capital firms based in San Francisco, United States

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Life sciences venture capital firms based in San Francisco, United States at a glance

As of Sep 14, 2026

35.7%Verified-email coverage

11.8Average contacts per company

1-10Median size (employees)

Sep 14, 2026Page data refreshed

Companies by employee count

1-10

132

11-50

51-200

501-1,000

10001+

Email recency for this list is measured across the whole United States list rather than for San Francisco, so it is reported there. Company counts and contact totals on this page are exact for San Francisco, over 170 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among life sciences venture capital firms, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in San Francisco, United States whose own description of what they do matches “life sciences venture capital firms”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names life sciences venture capital firms), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among life sciences venture capital firms, and records with no verified work email. Companies headquartered outside San Francisco are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 713 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 14, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Life sciences venture capital firms by metro in the United States

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names life sciences venture capital firms, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many life sciences venture capital firms are there based in San Francisco, United States?

RevenueBase identified 170 life sciences venture capital firms headquartered in San Francisco, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

M12, Microsoft's Venture Fund, headquartered in San Francisco, tops this list with the largest team on record.

Which city in the United States has the most life sciences venture capital firms?

New York leads the United States with 216 headquartered companies, followed by San Francisco (170) and Boston (107).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 713 verified decision-maker contacts tracked across these 170 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 14, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.