Company lists · Data refreshed September 2026

Top 25 Investigator site management software companies based in the United States

RevenueBase identified 1,369 investigator site management software companies headquartered in the United States as of September 2026 and tracks 139,520 professional contacts across them, including 65,614 with verified work emails. New York is the largest hub.

This list covers investigator site management software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 28, 2026 86% judged on-target in blind review
1,369Companies
139,520Contacts tracked
65,614Verified emails
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The 25 largest investigator site management software companies based in the United States

Ranked by team size
Top 25 of 1,369 investigator site management software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 28, 2026. RevenueBase Smart Search rates how each company's information relates to investigator site management software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceWaltham, MA, United StatesHQ checked Sep 28, 202610001+20,530 contacts →

Indirect evidence

“The PPD™ clinical research business of Thermo Fisher Scientific, the world leader in serving science, enables customers to accelerate innovation and drug development through…”

Source: RevenueBase Database · checked Sep 28, 2026
2Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 28, 202610001+19,257 contacts →

Indirect evidence

“Parexel is a leading global clinical research organization (CRO) providing insights-driven Clinical and Consulting solutions to the world’s life sciences industry.”

Source: RevenueBase Database · checked Sep 28, 2026
3Indirect evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 28, 202610001+10,632 contacts →

Indirect evidence

“Fortrea (Nasdaq: FTRE) is a leading global clinical research organization (CRO) dedicated to providing innovative clinical development solutions to the life sciences industry.”

Source: RevenueBase Database · checked Sep 28, 2026
4Indirect evidenceCincinnati, OH, United StatesHQ checked Sep 28, 20265,001-10,0005,960 contacts →

Indirect evidence

“Medpace is a scientifically-driven, global, full-service clinical contract research organization (CRO) providing Phase I-IV clinical development services to the biotechnology…”

Source: RevenueBase Database · checked Sep 28, 2026
5Indirect evidencePrinceton, NJ, United StatesHQ checked Sep 28, 202610001+5,220 contacts →

Indirect evidence

“As the drug development business of Laboratory Corporation of America Holdings (Labcorp) and the world’s most comprehensive drug development #CRO service company, we have helped…”

Source: RevenueBase Database · checked Sep 28, 2026
6Indirect evidenceRaleigh, NC, United StatesHQ checked Sep 28, 202610001+4,708 contacts →

Indirect evidence

“PRA is now an ICON plc company.”

Source: RevenueBase Database · checked Sep 28, 2026
7Indirect evidencePhiladelphia, PA, United StatesHQ checked Sep 28, 20261,001-5,0003,790 contacts →

Indirect evidence

“Clario, part of Thermo Fisher Scientific, is a leading provider of endpoint data solutions to the life sciences industry.”

Source: RevenueBase Database · checked Sep 28, 2026
8Indirect evidenceResearch Triangle Park, NC, United StatesHQ checked Sep 28, 20261,001-5,0003,440 contacts →

Indirect evidence

“Worldwide Clinical Trials (Worldwide) is a global CRO serving development-driven biopharmaceutical companies, with more than 4,400 professionals operating across more than 70…”

Source: RevenueBase Database · checked Sep 28, 2026
9Indirect evidenceNew York, NY, United StatesHQ checked Sep 28, 20261,001-5,0002,704 contacts →

Indirect evidence

“Medidata is powering smarter treatments and healthier people through digital solutions to support clinical trials.”

Source: RevenueBase Database · checked Sep 28, 2026
10Indirect evidenceMorrisville, NC, United StatesHQ checked Sep 28, 20261,001-5,0002,584 contacts →

Indirect evidence

“Premier Research International LLC (Premier) is a global leader in clinical research and consulting services with expertise in driving an efficient and effective path to market…”

Source: RevenueBase Database · checked Sep 28, 2026
11Indirect evidenceBlue Bell, PA, United StatesHQ checked Sep 28, 20261,001-5,0002,083 contacts →

Indirect evidence

“For 25+ years, Signant Health has been pioneering solutions and methodologies that propel clinical research programs toward regulatory success.”

Source: RevenueBase Database · checked Sep 28, 2026
12Indirect evidenceBethesda, MD, United StatesHQ checked Sep 28, 20261,001-5,0001,781 contacts →

Indirect evidence

“Precision for Medicine is an industry-leading global clinical research services organization, purpose-built to improve the clinical research and development process for new…”

Source: RevenueBase Database · checked Sep 28, 2026
13Indirect evidenceColumbia, MD, United StatesHQ checked Sep 28, 2026501-1,0001,581 contacts →

Indirect evidence

“Advarra provides the platform, insights, and expertise that make clinical trials more efficient and connected.”

Source: RevenueBase Database · checked Sep 28, 2026
14Partial evidenceCambridge, MA, United StatesHQ checked Sep 28, 20261,001-5,0001,580 contacts →

Partial evidence

“Cytel is the world’s leading data-science CRO, driving advancements in human health through robust analytics and innovative clinical trial software.”

Source: RevenueBase Database · checked Sep 28, 2026
15Indirect evidencePrinceton, NJ, United StatesHQ checked Sep 28, 20261,001-5,0001,293 contacts →

Indirect evidence

“ERT, the global clinical endpoint technology leader, and Bioclinica, a technological and scientific leader in medical imaging, is now the combined company of Clario.”

Source: RevenueBase Database · checked Sep 28, 2026
16Indirect evidenceConshohocken, PA, United StatesHQ checked Sep 28, 20261,001-5,0001,255 contacts →

Indirect evidence

“Suvoda is a global clinical trial technology company, now strengthened by our merger with Greenphire.”

Source: RevenueBase Database · checked Sep 28, 2026
17Partial evidenceCary, NC, United StatesHQ checked Sep 28, 20261,001-5,0001,103 contacts →

Partial evidence

“WCG is a true partner to research sponsors, CROs, sites and participants in navigating the clinical research journey.”

Source: RevenueBase Database · checked Sep 28, 2026
18Indirect evidenceCovington, KY, United StatesHQ checked Sep 28, 20261,001-5,0001,043 contacts →

Indirect evidence

“CTI Clinical Trial and Consulting Services is a global, privately held, research service organization, delivering a complete spectrum of clinical trial and consulting services…”

Source: RevenueBase Database · checked Sep 28, 2026
19Partial evidenceGaithersburg, MD, United StatesHQ checked Sep 28, 20261,001-5,000990 contacts →

Partial evidence

“Navitas Life Sciences is a global Clinical Research partner with over 35 years of expertise in Clinical, Regulatory, Safety, and Data Management solutions.”

Source: RevenueBase Database · checked Sep 28, 2026
20Indirect evidenceCary, NC, United StatesHQ checked Sep 28, 20261,001-5,000977 contacts →

Indirect evidence

“Allucent is on a mission to help bring new therapies to light by solving the distinct challenges of small and mid-sized biotech companies.”

Source: RevenueBase Database · checked Sep 28, 2026
21Partial evidenceDurham, NC, United StatesHQ checked Sep 28, 20261,001-5,000971 contacts →

Partial evidence

“Velocity is the world’s leading organization of fully integrated clinical research sites.”

Source: RevenueBase Database · checked Sep 28, 2026
22Indirect evidenceRockville, MD, United StatesHQ checked Sep 28, 20261,001-5,000961 contacts →

Indirect evidence

“Emmes is a Contract Research Organization delivering complex clinical trials through therapeutic expertise, scientific rigor, and technology-enabled execution.”

Source: RevenueBase Database · checked Sep 28, 2026
23Indirect evidenceDeerfield, IL, United StatesHQ checked Sep 28, 2026501-1,000960 contacts →

Indirect evidence

“Advanced Clinical is a clinical development and strategic resourcing organization committed to providing a better clinical experience across the drug development journey.”

Source: RevenueBase Database · checked Sep 28, 2026
24Indirect evidenceDurham, NC, United StatesHQ checked Sep 28, 20261,001-5,000915 contacts →

Indirect evidence

“BioAgilytix is a leading global contract research organization focused on supporting pharmaceutical and biotech partners in all phases of drug development.”

Source: RevenueBase Database · checked Sep 28, 2026
25Indirect evidenceCanton, MI, United StatesHQ checked Sep 28, 2026501-1,000876 contacts →

Indirect evidence

“MMS Holdings (MMS) is an award-winning, data-focused clinical research organization (CRO) that supports the pharmaceutical and biotech industries with a proven, scientific…”

Source: RevenueBase Database · checked Sep 28, 2026

Showing 25 of 1,369 investigator site management software companies based in the United States

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Investigator site management software companies based in the United States at a glance

As of Sep 28, 2026
47.0%Verified-email coverage
101.9Average contacts per company
11-50Median size (employees)
3.2%Largest-city concentration · New York
Sep 28, 2026Page data refreshed

Companies by employee count

1-10
460
11-50
528
51-200
229
201-500
72
501-1,000
30
1,001-5,000
36
5,001-10,000
2
10001+
11

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 1,369 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among investigator site management software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “investigator site management software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names investigator site management software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among investigator site management software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 65,614 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names investigator site management software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many investigator site management software companies are there based in the United States?

RevenueBase identified 1,369 investigator site management software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

PPD, headquartered in Waltham, tops this list with the largest team on record.

Which city has the most investigator site management software companies?

New York leads with 44 headquartered companies, followed by Miami (37) and Houston (36).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 65,614 verified decision-maker contacts tracked across these 1,369 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.