Company lists · Data refreshed September 2026

Top 25 Investigator-initiated trial sites based in the United States

RevenueBase identified 816 company matches for investigator-initiated trial sites associated with the United States as of September 2026 and tracks 47,342 professional contacts across them, including 19,558 with verified work emails. Miami is the largest hub.

This list covers company matches for investigator-initiated trial sites associated with the United States, found by RevenueBase SmartSearch using the meaning of business descriptions in its company graph at Exact. Ranked by professionals tracked, largest first. Rows show recorded descriptions where available, Exact search membership and the snapshot date. Data refreshed September 20, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list RevenueBase SmartSearch · Exact Recorded Sep 20, 2026 How this list was built
816Companies
47,342Contacts tracked
19,558Verified emails
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The 25 largest investigator-initiated trial sites based in the United States

Ranked by team size
Top 25 of 816 company matches for investigator-initiated trial sites based in the United States, ordered by professional contacts tracked in RevenueBase, largest first. Recorded Sep 20, 2026. The RevenueBase SmartSearch column shows Exact match membership in this saved search. Click a contact count to view that company's people. Totals use company locations recorded by RevenueBase; the displayed preview is a smaller selection.
#CompanyRevenueBase SmartSearchHeadquartersEmployeesContacts
1Exact matchWaltham, MA, United StatesHQ recorded Sep 20, 202610001+20,530 contacts →

Exact match

“The PPD™ clinical research business of Thermo Fisher Scientific, the world leader in serving science, enables customers to accelerate innovation and drug development through…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
2Exact matchRaleigh, NC, United StatesHQ recorded Sep 20, 202610001+4,708 contacts →

Exact match

“PRA is now an ICON plc company.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
3Exact matchLincoln, NE, United StatesHQ recorded Sep 20, 20261,001-5,0001,080 contacts →

Exact match

“Celerion, a leader in early clinical research, delivers Applied Translational Medicine.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
4Exact matchCovington, KY, United StatesHQ recorded Sep 20, 20261,001-5,0001,043 contacts →

Exact match

“CTI Clinical Trial and Consulting Services is a global, privately held, research service organization, delivering a complete spectrum of clinical trial and consulting services…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
5Exact matchDurham, NC, United StatesHQ recorded Sep 20, 20261,001-5,000971 contacts →

Exact match

“Velocity is the world’s leading organization of fully integrated clinical research sites.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
6Exact matchNashville, TN, United StatesHQ recorded Sep 20, 2026501-1,000868 contacts →

Exact match

“Sarah Cannon Research Institute (SCRI) is one of the world’s leading oncology research organizations, conducting community-based clinical trials.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
7Exact matchSalt Lake City, UT, United StatesHQ recorded Sep 20, 20261,001-5,000847 contacts →

Exact match

“CenExel is a leading integrated, wholly owned, nationwide clinical research site network comprised of 18 Centers of Excellence in major metropolitan areas across the U.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
8Exact matchRaleigh, NC, United StatesHQ recorded Sep 20, 20261,001-5,000758 contacts →

Exact match

“Caidya is a multi-therapeutic clinical research organization (CRO) serving innovators worldwide.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
9Exact matchHouston, TX, United StatesHQ recorded Sep 20, 2026501-1,000590 contacts →

Exact match

“DM Clinical Research is a network of clinical trial investigator sites with headquarters based out of Houston, Texas.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
10Exact matchDurham, NC, United StatesHQ recorded Sep 20, 202610001+532 contacts →

Exact match

“THIS PAGE IS NOT MONITORED.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
11Exact matchCoral Gables, FL, United StatesHQ recorded Sep 20, 2026501-1,000389 contacts →

Exact match

“Sitero is a next-generation, site-focused clinical research organization (CRO) for life sciences and institutional research organizations that helps get treatments to market safer…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
12Exact matchApex, NC, United StatesHQ recorded Sep 20, 2026501-1,000321 contacts →

Exact match

“Flourish Research is a fully integrated, multi-site clinical trial network serving sponsors and CROs across North America.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
13Exact matchAtlanta, GA, United StatesHQ recorded Sep 20, 2026201-500295 contacts →

Exact match

“Florence is a purpose-built platform that connects sponsors and sites to accelerate clinical trials, improve operational capacity, and reduce risk.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
14Exact matchMorrisville, NC, United StatesHQ recorded Sep 20, 2026201-500291 contacts →

Exact match

“Science 37 is a modern clinical research site that delivers trials directly to patients’ homes.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
15Exact matchDenver, CO, United StatesHQ recorded Sep 20, 20261,001-5,000260 contacts →

Exact match

“PCM Trials acquired EmVenio Research and Netherlands-based Clinical Trials Service in 2024.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
16Exact matchAustin, TX, United StatesHQ recorded Sep 20, 2026201-500254 contacts →

Exact match

“Elligo Health Research is an integrated research organization founded to bridge the gap between cutting-edge clinical trials and the patients who need them-an idea that sparked…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
17Exact matchColumbus, GA, United StatesHQ recorded Sep 20, 2026201-500251 contacts →

Exact match

“Centricity Research is an integrated research organization (IRO) with more than 40 wholly owned and integrated clinical research offices across North America.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
18Exact matchSan Jose, CA, United StatesHQ recorded Sep 20, 2026201-500229 contacts →

Exact match

“Since 2005, KlinEra has partnered with some of the largest pharmaceutical, biotech and device companies, providing innovative and customized clinical trial and research services.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
19Exact matchMaitland, FL, United StatesHQ recorded Sep 20, 2026201-500226 contacts →

Exact match

“Welcome to K2 Medical Research, a privately-owned clinical research facility with multiple locations in Florida, Tennessee, and Rhode Island.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
20Exact matchSan Antonio, TX, United StatesHQ recorded Sep 20, 2026501-1,000208 contacts →

Exact match

“Deeply rooted in community oncology centers globally, the START Center for Cancer Research ("START") provides patients with access to specialized Phase 1 clinical trials for novel…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
21Exact matchDenver, CO, United StatesHQ recorded Sep 20, 20261,001-5,000201 contacts →

Exact match

“EmVenio Clinical Research, a Professional Case Management subsidiary, operates from U.S.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
22Exact matchLake Worth, AZ, United StatesHQ recorded Sep 20, 2026501-1,000169 contacts →

Exact match

“Headlands Research is a leading globally integrated site organization with a mission to improve patients’ lives by advancing innovative medical therapies.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
23Exact matchOverland Park, KS, United StatesHQ recorded Sep 20, 2026201-500168 contacts →

Exact match

“Dr.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
24Exact matchAustin, TX, United StatesHQ recorded Sep 20, 202651-200166 contacts →

Exact match

“Founded in 2006, Tekton Research is a multi-specialty clinical research site organization conducting Phase 1-4 clinical trials across neurology and psychiatry, cardiometabolic…”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase
25Exact matchEdison, FL, United StatesHQ recorded Sep 20, 2026501-1,000161 contacts →

Exact match

“ERG is a leading U.S.”

Recorded in the RevenueBase company graph · Sep 20, 2026 · View company records in RevenueBase

Showing 25 of 816 investigator-initiated trial sites based in the United States

See the full list, filter by size, metro and specialty, and access 19,558 tracked professional contacts with verified work emails. Direct dials are available where recorded.

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Investigator-initiated trial sites based in the United States at a glance

As of Sep 20, 2026
41.3%Verified-email coverage
58.0Average contacts per company
11-50Median size (employees)
6.1%Largest-city concentration · Miami
Sep 20, 2026Page data refreshed

Companies by employee count

1-10
336
11-50
321
51-200
103
201-500
26
501-1,000
12
1,001-5,000
12
10001+
3

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 816 companies.

How this list was built

The recorded descriptions help you assess these company matches. Check a company’s website for its current services and locations.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Company records associated with the United States whose business descriptions match “investigator-initiated trial sites” by meaning at the Exact setting. Descriptions are compiled in the RevenueBase company graph from public websites, profiles and company information where available; they are not guaranteed quotations from the company's website.
RevenueBase SmartSearch
Describe a niche company in your own words to find businesses by meaning. Exact, Similar, Related and Broad control the breadth of RevenueBase SmartSearch. This saved list uses Exact. Each row's Exact match badge shows inclusion in that search, not an individual score or a service-quality judgment.
Public preview
The public preview omits records without a verified work email. Where headquarters information is recorded, preview rows are also filtered to this page’s location. Dataset totals and geographic summaries describe the full matched records before these preview filters.
Match quality
RevenueBase's August 25, 2026 study assessed 4,198 description/company pairs across matching settings. The publisher reports 86% good or better at Exact. This evaluates the method across queries; it does not audit this individual list. Recorded company descriptions, where available, help you judge each match yourself. Read the full methodology: how the lists are built and what the study measures.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every displayed company carries at least one verified work email. RevenueBase tracks 19,558 professional contacts with verified work emails across the full matched dataset. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
Record context
Company records and descriptions can change. Check the company's website for its current services and locations.

Frequently asked

What is RevenueBase SmartSearch?

RevenueBase SmartSearch finds niche companies by the meaning of their business descriptions in the RevenueBase company graph. Exact, Similar, Related and Broad control how closely companies must fit your description. This list uses Exact for “investigator-initiated trial sites”; each Exact match badge shows search membership, not an individual similarity or quality score.

How many investigator-initiated trial sites are there based in the United States?

RevenueBase identified 816 company matches for investigator-initiated trial sites associated with the United States as of September 2026, using the meaning of business descriptions at Exact. This is the recorded matched set in the RevenueBase company graph.

What is the largest company on this list?

PPD tops the displayed preview by professional contacts tracked in RevenueBase. Recorded headquarters appear in the company rows.

Which city has the most investigator-initiated trial sites?

Miami leads with 50 company records, followed by Houston (25) and Atlanta (15).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work limited free results with 500 credits to start. Upgrading provides access to the 19,558 professional contacts with verified work emails tracked across these 816 companies; direct dials are available where recorded.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.

Ready to reach these companies? Verified emails and direct dials for all 816 investigator-initiated trial sites based in the United States. Start with a free account, no credit card.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.