Company lists · Data refreshed September 2026

Top 25 Interoperability software companies for healthcare based in the United States

Name: Interoperability software companies for healthcare based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 28, 2026 379 companies tracked

RevenueBase identified 379 interoperability software companies for healthcare headquartered in the United States as of September 2026 and tracks 11,965 professional contacts across them, including 5,720 with verified work emails. Atlanta is the largest hub.

This list covers interoperability software companies for healthcare headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 28, 2026 86% judged on-target in blind review

379Companies

11,965Contacts tracked

5,720Verified emails

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The 25 largest interoperability software companies for healthcare based in the United States

Ranked by team size

Top 25 of 379 interoperability software companies for healthcare based in the United States, ranked by team size, largest first. Data refreshed Sep 28, 2026. RevenueBase Smart Search rates how each company's information relates to interoperability software companies for healthcare: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Datavant	Partial evidence	New York City, NY, United StatesHQ checked Sep 28, 2026	5,001-10,000	2,839 contacts →
	Partial evidence “Datavant is the data collaboration platform trusted for healthcare.” Source: RevenueBase Database · checked Sep 28, 2026
2	Edifecs	Indirect evidence	Bellevue, WA, United StatesHQ checked Sep 28, 2026	1,001-5,000	796 contacts →
	Indirect evidence “Edifecs, a Cotiviti business, provides market-leading technology to its payer and health system customers, which serve nearly 300 million people in the U.S.” Source: RevenueBase Database · checked Sep 28, 2026
3	Surescripts	Partial evidence	Arlington, VA, United StatesHQ checked Sep 28, 2026	501-1,000	706 contacts →
	Partial evidence “At Surescripts, we bring healthcare together to inform and accelerate decisions, helping keep patient care on track.” Source: RevenueBase Database · checked Sep 28, 2026
4	Ellkay	Partial evidence	Elmwood Park, NJ, United StatesHQ checked Sep 28, 2026	501-1,000	585 contacts →
	Partial evidence “ELLKAY is a trusted enterprise data management partner, driving innovation and connectivity across the healthcare ecosystem.” Source: RevenueBase Database · checked Sep 28, 2026
5	Rhapsody	Strong evidence	Boston, MA, United StatesHQ checked Sep 28, 2026	201-500	314 contacts →
	Strong evidence “Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: RevenueBase Database · checked Sep 28, 2026
6	Ehealth Technologies	Partial evidence	Fairport, NY, United StatesHQ checked Sep 28, 2026	501-1,000	306 contacts →
	Partial evidence “Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: RevenueBase Database · checked Sep 28, 2026
7	Concord Technologies	Strong evidence	Seattle, WA, United StatesHQ checked Sep 28, 2026	51-200	278 contacts →
	Strong evidence “Concord Technologies is a leading provider of secure document exchange, intelligent document processing, and interoperability solutions to healthcare providers, payers, and other…” Source: RevenueBase Database · checked Sep 28, 2026
8	Rldatix Data Solutions Group	Partial evidence	Chicago, IL, United StatesHQ checked Sep 28, 2026	51-200	200 contacts →
	Partial evidence “RLDatix Data Solutions Group (Galen Healthcare Solutions) is an award-winning, KLAS-ranked healthcare IT technical & professional services and solutions company providing…” Source: RevenueBase Database · checked Sep 28, 2026
9	Iatricsystems	Partial evidence	Daytona Beach, FL, United StatesHQ checked Sep 28, 2026	51-200	159 contacts →
	Partial evidence “iatricSystems is a healthcare technology company dedicated to helping healthcare organizations enhance their IT investments.” Source: RevenueBase Database · checked Sep 28, 2026
10	REDOX	Indirect evidence	Madison, WI, United StatesHQ checked Sep 28, 2026	51-200	141 contacts →
	Indirect evidence “Redox helps providers, payers, health tech vendors, EHRs, and Life Sciences power better care with real-time data exchange.” Source: RevenueBase Database · checked Sep 28, 2026
11	Ravsoft Solutions INC	Strong evidence	Mclean, VA, United StatesHQ checked Sep 28, 2026	51-200	135 contacts →
	Strong evidence “At RAVSoft Solutions, we specialize in delivering cutting-edge healthcare IT solutions with a strong focus on imaging, informatics, and AI integration, utilizing interoperability…” Source: RevenueBase Database · checked Sep 28, 2026
12	Medical Informatics Engineering	Partial evidence	Fort Wayne, IN, United StatesHQ checked Sep 28, 2026	51-200	124 contacts →
	Partial evidence “Long before they were buzzwords, market segments or government incentive programs, concepts like interoperability, data liquidity, patient engagement and meaningful use were…” Source: RevenueBase Database · checked Sep 28, 2026
13	Aaneel	Strong evidence	Tampa, FL, United StatesHQ checked Sep 28, 2026	51-200	120 contacts →
	Strong evidence “AaNeel is a healthcare interoperability platform built for payers and value-based care organizations.” Source: RevenueBase Database · checked Sep 28, 2026
14	Lantana Consulting Group	Partial evidence	East Thetford, VT, United StatesHQ checked Sep 28, 2026	51-200	117 contacts →
	Partial evidence “Lantana Consulting Group provides services and software solutions for standards-based health information exchange.” Source: RevenueBase Database · checked Sep 28, 2026
15	Clinical Architecture	Partial evidence	Carmel, IN, United StatesHQ checked Sep 28, 2026	51-200	115 contacts →
	Partial evidence “Clinical Architecture is the leading provider of innovative healthcare IT solutions focused on the quality and usability of clinical information.” Source: RevenueBase Database · checked Sep 28, 2026
16	Health Gorilla	Partial evidence	Coral Gables, FL, United StatesHQ checked Sep 28, 2026	51-200	109 contacts →
	Partial evidence “Health Gorilla, a designated QHIN under TEFCA, is a leading provider of interoperability solutions delivering secure, real-time access to structured, AI-ready health data.” Source: RevenueBase Database · checked Sep 28, 2026
17	Health Level Seven International	Partial evidence	Ann Arbor, MI, United StatesHQ checked Sep 28, 2026	11-50	100 contacts →
	Partial evidence “Founded in 1987, Health Level Seven (HL7) is an ANSI-accredited non-profit that empowers global health data interoperability by developing standards and enabling their adoption…” Source: RevenueBase Database · checked Sep 28, 2026
18	Clinisync	Indirect evidence	Hilliard, OH, United StatesHQ checked Sep 28, 2026	11-50	94 contacts →
	Indirect evidence “The Ohio Health Information Partnership is a non-profit entity whose mission is to assist physicians and other providers with the adoption and implement of health information…” Source: RevenueBase Database · checked Sep 28, 2026
19	Intellicentrics	Partial evidence	Flower Mound, TX, United StatesHQ checked Sep 28, 2026	51-200	89 contacts →
	Partial evidence “With a mission to use trust to make high-quality healthcare as accessible as a good cup of coffee, IntelliCentrics created the SEC³URE Ethos technology platform.” Source: RevenueBase Database · checked Sep 28, 2026
20	ZUS Health	Strong evidence	Boston, MA, United StatesHQ checked Sep 28, 2026	51-200	87 contacts →
	Strong evidence “Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded…” Source: RevenueBase Database · checked Sep 28, 2026
21	Amida Technology Solutions	Strong evidence	Washington, DC, United StatesHQ checked Sep 28, 2026	51-200	86 contacts →
	Strong evidence “Amida Technology Solutions, Inc.(Amida) is a software services company that solves the most complex challenges in data interoperability, data exchange, data governance, and data…” Source: RevenueBase Database · checked Sep 28, 2026
22	Cerner Healthcare Private Limited	Partial evidence	Indianapolis, IN, United StatesHQ checked Sep 28, 2026	11-50	78 contacts →
	Partial evidence “Cerner Healthcare Private Limited is a biotechnology company based out of United States.” Source: RevenueBase Database · checked Sep 28, 2026
23	RUVOS	Indirect evidence	Tallahassee, FL, United StatesHQ checked Sep 28, 2026	51-200	76 contacts →
	Indirect evidence “Formed in 2004, Ruvos is on a mission to deliver clever and efficient solutions to problems so that the world is a better place for the communities we serve.” Source: RevenueBase Database · checked Sep 28, 2026
24	MOXE	Partial evidence	Madison, WI, United StatesHQ checked Sep 28, 2026	51-200	75 contacts →
	Partial evidence “Moxe connects the healthcare ecosystem with high quality, meaningful data to drive better outcomes.” Source: RevenueBase Database · checked Sep 28, 2026
25	Manifest Medex	Indirect evidence	Riverside, CA, United StatesHQ checked Sep 28, 2026	51-200	68 contacts →
	Indirect evidence “Manifest MedEx is California’s largest nonprofit health data network, powering the high-resolution, whole person data exchange needed to optimize health.” Source: RevenueBase Database · checked Sep 28, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: interoperability software companies for healthcare. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names interoperability software companies for healthcare.
Partial evidence: Its own public description names part of interoperability software companies for healthcare, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name interoperability software companies for healthcare. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 379 interoperability software companies for healthcare based in the United States

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Interoperability software companies for healthcare based in the United States at a glance

As of Sep 28, 2026

47.8%Verified-email coverage

31.6Average contacts per company

11-50Median size (employees)

2.4%Largest-city concentration · Atlanta

Sep 28, 2026Page data refreshed

Companies by employee count

1-10

130

11-50

169

51-200

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 379 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among interoperability software companies for healthcare, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “interoperability software companies for healthcare”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names interoperability software companies for healthcare), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among interoperability software companies for healthcare, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 5,720 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names interoperability software companies for healthcare, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many interoperability software companies for healthcare are there based in the United States?

RevenueBase identified 379 interoperability software companies for healthcare headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Datavant, headquartered in New York City, tops this list with the largest team on record.

Which city has the most interoperability software companies for healthcare?

Atlanta leads with 9 headquartered companies, followed by San Francisco (8) and Austin (7).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 5,720 verified decision-maker contacts tracked across these 379 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.