Company lists · Data refreshed September 2026
Top 25 Interoperability and integration software companies based in the United States
RevenueBase identified 331 interoperability and integration software companies headquartered in the United States as of September 2026 and tracks 8,203 professional contacts across them, including 3,391 with verified work emails. Houston is the largest hub.
This list covers interoperability and integration software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest interoperability and integration software companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 2,491 contacts → | ||||
Indirect evidence “Connect everything to achieve anything™ #TeamBoomi” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 2 | 522 contacts → | ||||
Partial evidence “Cleo is a supply chain orchestration software company that connects, automates, and optimizes the critical processes that keep goods and data moving.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 3 | 314 contacts → | ||||
Strong evidence “Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 4 | 306 contacts → | ||||
Indirect evidence “Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 5 | 270 contacts → | ||||
Partial evidence “Blackstone eIT is a leading System Integrator (SI) and Independent Software Vendor (ISV), globally dedicated to engineering transformative enterprise solutions and intelligent…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 6 | 141 contacts → | ||||
Indirect evidence “Redox helps providers, payers, health tech vendors, EHRs, and Life Sciences power better care with real-time data exchange.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 7 | 110 contacts → | ||||
Partial evidence “CTR is a system integration company that provides technology solutions and support to all manner of businesses worldwide.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 8 | 109 contacts → | ||||
Partial evidence “Health Gorilla, a designated QHIN under TEFCA, is a leading provider of interoperability solutions delivering secure, real-time access to structured, AI-ready health data.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 9 | 105 contacts → | ||||
Indirect evidence “At APPSeCONNECT, we do more than connect apps.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 10 | 102 contacts → | ||||
Partial evidence “OpsHub is the leading provider of integration and migration solutions for the ALM, CRM, and DevOps tool chains.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 11 | 101 contacts → | ||||
Indirect evidence “We connect your business data to AI, and to everything else.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 12 | 99 contacts → | ||||
Partial evidence “Paragon is the leading integration infrastructure platform for AI.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 13 | 93 contacts → | ||||
Strong evidence “American Business Solutions Inc (ABSI) is a software integration company.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 14 | 86 contacts → | ||||
Strong evidence “Amida Technology Solutions, Inc.(Amida) is a software services company that solves the most complex challenges in data interoperability, data exchange, data governance, and data…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 15 | 80 contacts → | ||||
Partial evidence “OneHQ is a SaaS (Software as a Service) solution focused on reshaping the Insurance Distribution Industry.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 16 | 64 contacts → | ||||
Indirect evidence “ClinDCast is a full-service Healthcare IT product solutions and services company headquartered in the Wesley Chapel, Florida.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 17 | 59 contacts → | ||||
Partial evidence “Lysi is a diverse, dynamic, and versatile technology integration company specializing in the intersection of technology and business process management.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 18 | 51 contacts → | ||||
Indirect evidence “Since 2005, Intellective has been solving complex business challenges with Fortune companies across multiple industries.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 19 | 49 contacts → | ||||
Partial evidence “MindCloud is a software company that builds and maintains custom connections between your software and other platforms so you can eliminate manual data entry and start automating…” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 20 | 45 contacts → | ||||
Partial evidence “Nova Module is a leading provider of high value application integration consulting and solutions.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 21 | 45 contacts → | ||||
Partial evidence “LinkToAny powers mission-critical integrations and onboarding experiences from the smallest Commerce startups to Fortune 500 platforms such as Shopify, PayPal and Lightspeed.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 22 | 45 contacts → | ||||
Strong evidence “LogiCoy is dedicated to solving complex integration and interoperability challenges in healthcare, enabling providers to deliver seamless and efficient patient care.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 23 | 42 contacts → | ||||
Indirect evidence “THE CONCENTRIC EXPERIENCE We are a team of technology consultants and integrators helping progressive government leaders implement a roadmap to efficiency.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 24 | 42 contacts → | ||||
Partial evidence “DAn Solutions specializes in systems integration solutions for a variety of business management operations.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
| 25 | 39 contacts → | ||||
Indirect evidence “Twenty five years in healthcare IT teaches you that the hardest problems are rarely the ones on the agenda.” Source: RevenueBase Database · checked Sep 28, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: interoperability and integration software companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names interoperability and integration software companies.
- Partial evidence
- Its own public description names part of interoperability and integration software companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name interoperability and integration software companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 331 interoperability and integration software companies based in the United States
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Interoperability and integration software companies based in the United States at a glance
As of Sep 28, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 331 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among interoperability and integration software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “interoperability and integration software companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names interoperability and integration software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among interoperability and integration software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 3,391 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names interoperability and integration software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many interoperability and integration software companies are there based in the United States?
RevenueBase identified 331 interoperability and integration software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
BOOMI, headquartered in Conshohocken, tops this list with the largest team on record.
Which city has the most interoperability and integration software companies?
Houston leads with 8 headquartered companies, followed by New York (8) and Columbus (7).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 3,391 verified decision-maker contacts tracked across these 331 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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