Company lists · Data refreshed September 2026

Top 25 Innovation hubs based in the United States

Name: Innovation hubs based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 20, 2026 2,554 companies tracked

RevenueBase identified 2,554 innovation hubs headquartered in the United States as of September 2026 and tracks 31,699 professional contacts across them, including 5,722 with verified work emails. New York is the largest hub.

This list covers innovation hubs headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 20, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 20, 2026 86% judged on-target in blind review

2,554Companies

31,699Contacts tracked

5,722Verified emails

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The 25 largest innovation hubs based in the United States

Ranked by team size

Top 25 of 2,554 innovation hubs based in the United States, ranked by team size, largest first. Data refreshed Sep 20, 2026. RevenueBase Smart Search rates how each company's information relates to innovation hubs: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Y Combinator	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 20, 2026	n/a	3,283 contacts →
	Indirect evidence “Y Combinator is the leading startup accelerator for entrepreneurs.” Source: RevenueBase Database · checked Sep 20, 2026
2	Microsoft For Startups	Indirect evidence	Redmond, WA, United StatesHQ checked Sep 20, 2026	10001+	1,533 contacts →
	Indirect evidence “Microsoft for Startups is a digital ecosystem removing barriers to building a company with free access to technology, coaching, and support for founders in any stage of…” Source: RevenueBase Database · checked Sep 20, 2026
3	Company	Indirect evidence	NY, United StatesHQ checked Sep 20, 2026	n/a	1,480 contacts →
	Indirect evidence “Company is a curated collection of startups, entrepreneurs, and enterprises working towards the realization of impactful ideas, together.” Source: RevenueBase Database · checked Sep 20, 2026
4	Plug And Play	Partial evidence	Sunnyvale, CA, United StatesHQ checked Sep 20, 2026	501-1,000	1,240 contacts →
	Partial evidence “Plug and Play is a global innovation platform founded in Silicon Valley in 2006.” Source: RevenueBase Database · checked Sep 20, 2026
5	PARC	Indirect evidence	Palo Alto, CA, United StatesHQ checked Sep 20, 2026	1,001-5,000	618 contacts →
	Indirect evidence “PARC is now part of SRI, an independent nonprofit research institute with deep roots in Silicon Valley that's had a profound impact on every one of our lives.” Source: RevenueBase Database · checked Sep 20, 2026
6	REM And Company	Indirect evidence	St. Louis, United StatesHQ checked Sep 20, 2026	201-500	577 contacts →
	Indirect evidence “49% of Businesses fail within their first 5 years.” Source: RevenueBase Database · checked Sep 20, 2026
7	Startup Grind	Indirect evidence	Palo Alto, CA, United StatesHQ checked Sep 20, 2026	n/a	483 contacts →
	Indirect evidence “Startup Grind is the leading global startup community dedicated to fostering the growth of early-stage companies.” Source: RevenueBase Database · checked Sep 20, 2026
8	TIE	Indirect evidence	Santa Clara, CA, United StatesHQ checked Sep 20, 2026	n/a	480 contacts →
	Indirect evidence “TiE Inc, also known as TiE Global is a non-profit organization with the mission of fostering entrepreneurship, through mentoring, networking and education.” Source: RevenueBase Database · checked Sep 20, 2026
9	Novatr	Indirect evidence	Wilmington, DE, United StatesHQ checked Sep 20, 2026	51-200	316 contacts →
	Indirect evidence “Architecture, Engineering, and Construction (AEC) is among the least digitised industries in the world.” Source: RevenueBase Database · checked Sep 20, 2026
10	CIC Cambridge Innovation Center	Partial evidence	Cambridge, MA, United StatesHQ checked Sep 20, 2026	201-500	315 contacts →
	Partial evidence “CIC is the global leader in driving innovation at scale.” Source: RevenueBase Database · checked Sep 20, 2026
11	Awesome INC	Indirect evidence	Lexington, KY, United StatesHQ checked Sep 20, 2026	n/a	279 contacts →
	Indirect evidence “Based in Lexington, Kentucky, Awesome Inc: 🤝 Grows community through events, education, and entrepreneurship Throws the largest pitch competition in the region, 5 Across Helps…” Source: RevenueBase Database · checked Sep 20, 2026
12	Wits Innovation LAB	Partial evidence	Camarillo, CA, United StatesHQ checked Sep 20, 2026	501-1,000	273 contacts →
	Partial evidence “Wits Innovation Lab is a hub of cutting-edge technology, helping businesses of all sizes-startups, SMBs, and enterprises-innovate, scale, and lead.” Source: RevenueBase Database · checked Sep 20, 2026
13	ODF	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 20, 2026	n/a	258 contacts →
	Indirect evidence “Our mission is to help more people start better startups.” Source: RevenueBase Database · checked Sep 20, 2026
14	NY Creates	Partial evidence	Albany, NY, United StatesHQ checked Sep 20, 2026	1,001-5,000	255 contacts →
	Partial evidence “The New York Center for Research, Economic Advancement, Technology, Engineering, and Science (NY Creates) is a world-leading R&D innovation hub and commercialization facilitator.” Source: RevenueBase Database · checked Sep 20, 2026
15	Bridge For Billions	Indirect evidence	New York, NY, United StatesHQ checked Sep 20, 2026	n/a	231 contacts →
	Indirect evidence “Bridge for Billions is a global social enterprise on a mission to build more inclusive and sustainable economies through early-stage entrepreneurship.” Source: RevenueBase Database · checked Sep 20, 2026
16	The Mart	Indirect evidence	Chicago, IL, United StatesHQ checked Sep 20, 2026	51-200	186 contacts →
	Indirect evidence “THE MART is the largest privately held commercial building in the United States: it encompasses 4.2 million gross square feet, spans two city blocks, rises 25 stories, and is…” Source: RevenueBase Database · checked Sep 20, 2026
17	United Technologies Research Center	Indirect evidence	East Hartford, CT, United StatesHQ checked Sep 20, 2026	501-1,000	171 contacts →
	Indirect evidence “United Technologies Research Center (UTRC) models, makes, powers, connects and secures the next generation of UTC products in order to transform entire industries and set new…” Source: RevenueBase Database · checked Sep 20, 2026
18	Aximsoft	Indirect evidence	San Ramon, CA, United StatesHQ checked Sep 20, 2026	51-200	145 contacts →
	Indirect evidence “Aximsoft facilitates startups to build the future.” Source: RevenueBase Database · checked Sep 20, 2026
19	Protocol Labs	Partial evidence	San Francisco, CA, United StatesHQ checked Sep 20, 2026	201-500	131 contacts →
	Partial evidence “Protocol Labs is an innovation network driving breakthroughs in computing to push humanity forward.” Source: RevenueBase Database · checked Sep 20, 2026
20	Genesys Systems Integrator	Indirect evidence	Kansas City, MO, United StatesHQ checked Sep 20, 2026	51-200	122 contacts →
	Indirect evidence “Established in 1997, GENESYS is a learning organization.” Source: RevenueBase Database · checked Sep 20, 2026
21	Founders, INC	Indirect evidence	San Francisco, CA, United StatesHQ checked Sep 20, 2026	n/a	116 contacts →
	Indirect evidence “sq.” Source: RevenueBase Database · checked Sep 20, 2026
22	Entrepreneurs Roundtable Accelerator	Indirect evidence	NY, United StatesHQ checked Sep 20, 2026	n/a	114 contacts →
	Indirect evidence “Entrepreneurs Roundtable Accelerator (ERA) is New York City’s leading technology accelerator and early-stage venture capital fund.” Source: RevenueBase Database · checked Sep 20, 2026
23	Biolabs	Indirect evidence	Cambridge, MA, United StatesHQ checked Sep 20, 2026	51-200	110 contacts →
	Indirect evidence “BioLabs are the premier co-working spaces for life science startups- unique places where you can test, develop and grow your game-changing ideas.” Source: RevenueBase Database · checked Sep 20, 2026
24	Vation Ventures	Indirect evidence	Denver, CO, United StatesHQ checked Sep 20, 2026	11-50	104 contacts →
	Indirect evidence “Every day we help forward-thinking leaders reshape how they innovate, providing them with access to powerful tools, technologies, and an ecosystem unlike anything currently in the…” Source: RevenueBase Database · checked Sep 20, 2026
25	Nasdaq Entrepreneurial Center	Indirect evidence	Palo Alto, CA, United StatesHQ checked Sep 20, 2026	11-50	103 contacts →
	Indirect evidence “The Nasdaq Center is an invaluable and prestigious resource for founders and leaders worldwide.” Source: RevenueBase Database · checked Sep 20, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: innovation hubs. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names innovation hubs.
Partial evidence: Its own public description names part of innovation hubs, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name innovation hubs. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 2,554 innovation hubs based in the United States

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Innovation hubs based in the United States at a glance

As of Sep 20, 2026

18.1%Verified-email coverage

12.4Average contacts per company

1-10Median size (employees)

5.1%Largest-city concentration · New York

Sep 20, 2026Page data refreshed

Companies by employee count

1-10

1,719

11-50

595

51-200

134

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 2,554 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among innovation hubs, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “innovation hubs”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names innovation hubs), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among innovation hubs, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 5,722 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Innovation hubs by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names innovation hubs, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many innovation hubs are there based in the United States?

RevenueBase identified 2,554 innovation hubs headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Y Combinator, headquartered in San Francisco, tops this list with the largest team on record.

Which city has the most innovation hubs?

New York leads with 129 headquartered companies, followed by San Francisco (116) and Los Angeles (63).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 5,722 verified decision-maker contacts tracked across these 2,554 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.