Company lists · Data refreshed September 2026

Top 22 Informatics companies based in Chicago, United States

RevenueBase identified 42 informatics companies headquartered in Chicago, United States as of September 2026 and tracks 3,832 professional contacts across them, including 2,077 with verified work emails. Across the United States, San Diego is the largest hub for this category (157 companies); Chicago has 42.

This list covers informatics companies headquartered in Chicago, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 14, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 14, 2026 86% judged on-target in blind review
42Companies
3,832Contacts tracked
2,077Verified emails
Explore this list → Free signup · no credit card · 500 free credits

The 22 largest informatics companies based in Chicago, United States

Ranked by team size
Top 22 of 42 informatics companies based in Chicago, United States, ranked by team size, largest first. Data refreshed Sep 14, 2026. RevenueBase Smart Search rates how each company's information relates to informatics companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261,001-5,0002,758 contacts →

Indirect evidence

“Tempus is a technology company advancing precision medicine through the practical application of artificial intelligence in healthcare.”

Source: RevenueBase Database · checked Sep 14, 2026
2Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 2026501-1,000465 contacts →

Indirect evidence

“Strategic Systems International (SSI) is Chicago-headquartered Advanced Analytics and Software Engineering firm that builds data-driven applications for Tech Companies and…”

Source: RevenueBase Database · checked Sep 14, 2026
3Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202651-20080 contacts →

Indirect evidence

“Nucleai Brings AI-powered spatial biology technology to the forefront of precision medicine to improve drug development, clinical treatment decisions, and patient outcomes.”

Source: RevenueBase Database · checked Sep 14, 2026
4Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202651-20076 contacts →

Indirect evidence

“Performalytic Corp, headquartered in Naperville, IL, is a leading implementer and thought leader of Analytics and Business Intelligence solutions for many Fortune500 companies.”

Source: RevenueBase Database · checked Sep 14, 2026
5Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5062 contacts →

Indirect evidence

“STAT Analysis Corporation (STAT) is a full-service analytical support laboratory that serves the environmental and industrial hygiene industries.”

Source: RevenueBase Database · checked Sep 14, 2026
6Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202651-20053 contacts →

Indirect evidence

“Vodori’s mission is to transform lives by bringing regulated products to market faster.”

Source: RevenueBase Database · checked Sep 14, 2026
7Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5046 contacts →

Indirect evidence

“Prenosis is transforming clinical diagnosis with artificial intelligence that leverages holistic molecular and clinical data.”

Source: RevenueBase Database · checked Sep 14, 2026
8Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5035 contacts →

Indirect evidence

“mcSquared.AI specializes in accelerating analytics for businesses seeking the quickest ROI on their cloud and big data investments.”

Source: RevenueBase Database · checked Sep 14, 2026
9Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5029 contacts →

Indirect evidence

“SimBioSys is a pioneering TechBio company leveraging artificial intelligence and biophysical modeling to harness the power of spatial biophysics to redefine precision medicine…”

Source: RevenueBase Database · checked Sep 14, 2026
10Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202651-20029 contacts →

Indirect evidence

“We are a team of data scientists, engineers, and consultants committed to harnessing the vast powers of machine learning to solve distinct problems.”

Source: RevenueBase Database · checked Sep 14, 2026
11Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5028 contacts →

Indirect evidence

“Cardio Diagnostics is a biotechnology company that makes cardiovascular disease prevention and early detection more accessible, personalized, and precise.”

Source: RevenueBase Database · checked Sep 14, 2026
12Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-5019 contacts →

Indirect evidence

“WCG KMR Group is a global leader in the provision and analysis of benchmarking and other data for the biopharmaceutical industry.”

Source: RevenueBase Database · checked Sep 14, 2026
13Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-1017 contacts →

Indirect evidence

“BiomeSense is a pioneering life sciences startup focused on harnessing the power of the gut microbiome to revolutionize personalized medicine.”

Source: RevenueBase Database · checked Sep 14, 2026
14Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-108 contacts →

Indirect evidence

“Our mandate is to accelerate the development and validation of liquid biopsy assays to improve the outcomes of patients with cancer.”

Source: RevenueBase Database · checked Sep 14, 2026
15Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-108 contacts →

Indirect evidence

“BiopharmIQ provides data and services to help sales/BD teams and investors.”

Source: RevenueBase Database · checked Sep 14, 2026
16Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-107 contacts →

Indirect evidence

“We build precision genomics platforms that enable real-time monitoring, early detection, and lasting safety for the industries that sustain us.”

Source: RevenueBase Database · checked Sep 14, 2026
17Indirect evidenceChicago, United StatesHQ checked Sep 14, 20261-107 contacts →

Indirect evidence

“Ellis Bio is a biotechnology tools company driven by a vision to revolutionize genomic technologies and make cutting-edge epigenomic tools accessible to researchers and clinicians…”

Source: RevenueBase Database · checked Sep 14, 2026
18Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202651-2005 contacts →

Indirect evidence

“Gene Matrix | Global Biotech Leader in Precision Genomics and AI Healthcare Gene Matrix is a next-generation biotechnology company transforming the landscape of healthcare through…”

Source: RevenueBase Database · checked Sep 14, 2026
19Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-104 contacts →

Indirect evidence

“Attribute Analytics is revolutionizing the food industry through cutting-edge technology that leverages sensory data.”

Source: RevenueBase Database · checked Sep 14, 2026
20Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-103 contacts →

Indirect evidence

“PersonaDx was founded on decades of paradigm-shifting metastasis research at the University of Chicago by Dr.”

Source: RevenueBase Database · checked Sep 14, 2026
21Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 202611-502 contacts →

Indirect evidence

“iSimplifyMe is an AI Infrastructure and Orchestration firm.”

Source: RevenueBase Database · checked Sep 14, 2026
22Indirect evidenceChicago, IL, United StatesHQ checked Sep 14, 20261-102 contacts →

Indirect evidence

“Bainom is developing an artificial intelligence (AI) and machine learning (ML) driven bioinformatics platform that accelerates translational biology and advances precision…”

Source: RevenueBase Database · checked Sep 14, 2026

Showing 22 of 42 informatics companies based in Chicago, United States

See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 2,077 reachable decision-makers.

Free signup · no credit card

View the full list →

Informatics companies based in Chicago, United States at a glance

As of Sep 14, 2026
54.2%Verified-email coverage
91.2Average contacts per company
1-10Median size (employees)
Sep 14, 2026Page data refreshed

Companies by employee count

1-10
23
11-50
9
51-200
8
501-1,000
1
1,001-5,000
1

Email recency for this list is measured across the whole United States list rather than for Chicago, so it is reported there. Company counts and contact totals on this page are exact for Chicago, over 42 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among informatics companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in Chicago, United States whose own description of what they do matches “informatics companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names informatics companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among informatics companies, and records with no verified work email. Companies headquartered outside Chicago are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 2,077 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 14, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names informatics companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many informatics companies are there based in Chicago, United States?

RevenueBase identified 42 informatics companies headquartered in Chicago, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Tempus AI, headquartered in Chicago, tops this list with the largest team on record.

Which city in the United States has the most informatics companies?

San Diego leads the United States with 157 headquartered companies, followed by New York (125) and San Francisco (124). Chicago has 42.

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 2,077 verified decision-maker contacts tracked across these 42 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 14, 2026.

Ready to reach these companies? Verified emails and direct dials for all 42 informatics companies based in Chicago, United States. Start with a free account, no credit card.

Download this list →

Related lists

About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.