Company lists · Data refreshed September 2026

Top 25 Independent pharmacy software based in the United States

RevenueBase identified 282 independent pharmacy software headquartered in the United States as of September 2026 and tracks 9,627 professional contacts across them, including 4,201 with verified work emails and 4,274 with mobile numbers. Houston is the largest hub.

This list covers independent pharmacy software headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 3, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row Match evidence on every row Refreshed Sep 3, 2026 86% judged on-target in blind review
282Companies
9,627Contacts tracked
4,201Verified emails
4,274Mobile numbers
Unlock all 282 companies Free signup · no credit card · 500 free credits

The 25 largest independent pharmacy software based in the United States

Ranked by team size
Top 25 of 282 independent pharmacy software based in the United States, ranked by team size, largest first. Data refreshed Sep 3, 2026. Evidence rates how directly each company's own description names independent pharmacy software: strong (names it), partial (names part of it), indirect (matched on its full profile rather than the summary shown). Click a count to unlock that company's people.
#CompanyHeadquartersEmployeesContacts
1
Remedi Seniorcare PharmacyIndirect evidence
Baltimore, MD, United StatesHQ checked Sep 3, 20261,001-5,000673

“Remedi SeniorCare, a Clarest Health division, is transforming medication management for long-term care facilities including Skilled Nursing Facilities, Assisted Living/Memory Care…”

Source: company website · checked Sep 3, 2026
2
OutcomesIndirect evidence
Orlando, FL, United StatesHQ checked Sep 3, 2026501-1,000598

“Outcomes® unites technology and clinical relationships through a connected healthcare network to drive better outcomes.”

Source: company website · checked Sep 3, 2026
3
IAPartial evidence
Indianapolis, NY, United StatesHQ checked Sep 3, 2026501-1,000563

“iA® (Innovation Associates®) is a pharmacy fulfillment company that provides an integrated platform of capabilities to support centralized pharmacy fulfillment and community…”

Source: company website · checked Sep 3, 2026
4
Drfirst, INCIndirect evidence
Arlington, VA, United StatesHQ checked Sep 3, 2026201-500435

“DrFirst has been transforming medication management for 25 years, helping providers and patients navigate a complex and often fragmented healthcare system.”

Source: company website · checked Sep 3, 2026
5
Parata SystemsPartial evidence
Durham, NC, United StatesHQ checked Sep 3, 202610001+404

“At Parata, a BD company, we power pharmacies to help people lead healthier lives.”

Source: company website · checked Sep 3, 2026
6
Redsail TechnologiesPartial evidence
Spartanburg, SC, United StatesHQ checked Sep 3, 2026501-1,000354

“RedSail Technologies, LLC, is empowering pharmacy and transforming care with a network of over 11,500+ pharmacies serving more than 8 million patients monthly.”

Source: company website · checked Sep 3, 2026
7
Capsa HealthcarePartial evidence
Canal Winchester, OR, United StatesHQ checked Sep 3, 2026501-1,000272

“Across the healthcare continuum, Capsa stands out as the leader in purposefully designed, integrated solutions for pharmacy automation, medication management, and point-of-care…”

Source: company website · checked Sep 3, 2026
8Dallas, TX, United StatesHQ checked Sep 3, 202651-200272

Pharmaceutical Strategies Group (PSG) is the leading pharmacy intelligence and technology company providing cutting-edge drug cost-management solutions.”

Source: company website · checked Sep 3, 2026
9
Empirx HealthPartial evidence
Montvale, NJ, United StatesHQ checked Sep 3, 2026201-500260

“EmpiRx Health is the leading clinically-driven pharmacy benefits management (PBM) company that puts the pharmacist at the center of its unique Medication Optimization operating…”

Source: company website · checked Sep 3, 2026
10
Mckesson Specialty HealthIndirect evidence
Scottsdale, AZ, United StatesHQ checked Sep 3, 202610001+255

“McKesson Specialty Health is a company based out of 4343 North Scottsdale Road Suite 150, Scottsdale, Arizona, United States.”

Source: company website · checked Sep 3, 2026
11
AlixarxPartial evidence
Plano, TX, United StatesHQ checked Sep 3, 2026501-1,000229

“AlixaRx provides advanced pharmacy services to post‐acute healthcare facilities through a new model that leverages technology to deliver medication therapy management.”

Source: company website · checked Sep 3, 2026
12
Pdx, INCPartial evidence
Fort Worth, TX, United StatesHQ checked Sep 3, 2026501-1,000225

“A leading provider of healthcare technology for over 30 years to nearly pharmacies nationwide, our 650 person team of developers, design architects, and customer support…”

Source: company website · checked Sep 3, 2026
13Irving, TX, United StatesHQ checked Sep 3, 2026201-500172

“PioneerRx Pharmacy Software has a deep understanding of the challenges faced by independent pharmacies.”

Source: company website · checked Sep 3, 2026
14
Transaction Data SystemsStrong evidence
Orlando, MO, United StatesHQ checked Sep 3, 2026501-1,000166

“For the past 45 years, TDS has been dedicated to the success of independent pharmacy.”

Source: company website · checked Sep 3, 2026
15
PipelinerxPartial evidence
San Francisco, CA, United StatesHQ checked Sep 3, 202651-200148

“At PipelineRx our vision is for every provider and every patient to have access to high-quality pharmacy services anytime, anywhere.”

Source: company website · checked Sep 3, 2026
16
CompleterxStrong evidence
Houston, TX, United StatesHQ checked Sep 3, 2026201-500138

“CompleteRx is a leading independent provider of pharmacy management and consulting services to acute care hospitals.”

Source: company website · checked Sep 3, 2026
17
Verity SolutionsStrong evidence
Kirkland, WA, United StatesHQ checked Sep 3, 202651-200136

“Verity Solutions is an award-winning leader in software and services that optimize pharmacy supply chain outcomes for better financial results and patient care.”

Source: company website · checked Sep 3, 2026
18
Nucara PharmacyPartial evidence
Conrad, IA, United StatesHQ checked Sep 3, 2026201-500117

“Our goal is to deliver the best pharmacy value without sacrificing the quality of care prized by our patients.”

Source: company website · checked Sep 3, 2026
19
Liberty SoftwareStrong evidence
Southlake, TX, United StatesHQ checked Sep 3, 202651-200110

“Liberty Software began as an independent computer service company serving the computer needs of community pharmacies across the South.”

Source: company website · checked Sep 3, 2026
20
Macro HelixPartial evidence
Atlanta, TX, United StatesHQ checked Sep 3, 2026201-500109

“Macro Helix is focused on assisting pharmacy providers as they strive to improve financial performance, increase operating efficiencies, and maintain regulatory compliance.”

Source: company website · checked Sep 3, 2026
21
3am Technologies, LLCIndirect evidence
Joelton, TN, United StatesHQ checked Sep 3, 202611-50108

“3AM Technologies presents ServeRx and SimServeRx ServeRx™ is a complete medication management system that provides a unique closed loop solution for medication management from…”

Source: company website · checked Sep 3, 2026
22
IntelliguardIndirect evidence
Columbus, CO, United StatesHQ checked Sep 3, 202651-200104

“Intelliguard is a purpose-built healthcare technology company transforming how hospitals manage medications.”

Source: company website · checked Sep 3, 2026
23
LumistryPartial evidence
Boiling Springs, SC, United StatesHQ checked Sep 3, 202651-200103

“Lumistry serves over pharmacies globally, helping them transform their businesses to improve adherence, reduce operating costs and increase revenue.”

Source: company website · checked Sep 3, 2026
24
Pillr HealthPartial evidence
Boca Raton, FL, United StatesHQ checked Sep 3, 202651-200101

“Pillr Health is a leading provider of innovative solutions designed to optimize and streamline pharmacy operations.”

Source: company website · checked Sep 3, 2026
25
primerx.ioPartial evidence
Uniondale, NY, United StatesHQ checked Sep 3, 202651-20091

“As pharmacists play an increasingly important role in patient care, the need has never been greater for technology-based solutions that add efficiency to operations and facilitate…”

Source: company website · checked Sep 3, 2026

Showing 25 of 282 independent pharmacy software based in the United States

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Independent pharmacy software based in the United States at a glance

As of Sep 3, 2026
11-50Median size (employees)
HoustonLargest hub · 8 HQs
4,274Contacts with mobile numbers
Sep 3, 2026Data refreshed

Companies by employee count

1-10
113
11-50
93
51-200
45
201-500
13
501-1,000
12
1,001-5,000
3
10001+
2

Verified emails by last verification

0–30
0
31–60
346
61–90
2,417
90–180
1,419
180+
19

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among independent pharmacy software, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “independent pharmacy software”. Matching reads each company's description, not its industry code or its name.
What we exclude
Companies whose own description does not clearly place them among independent pharmacy software, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 4,201 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 3, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

How many independent pharmacy software are there based in the United States?

RevenueBase identified 282 independent pharmacy software headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Remedi Seniorcare Pharmacy, headquartered in Towson, tops this list with the largest team on record.

Which city has the most independent pharmacy software?

Houston leads with 8 headquartered companies, followed by New York (8) and Orlando (6).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 4,201 verified decision-maker contacts tracked across these 282 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 3, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.