Company lists · Data refreshed September 2026
Top 25 Heart disease biotech startups based in the United States
RevenueBase identified 100 heart disease biotech startups headquartered in the United States as of September 2026 and tracks 2,249 professional contacts across them, including 707 with verified work emails. Houston is the largest hub.
This list covers heart disease biotech startups headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest heart disease biotech startups based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 440 contacts → | ||||
Indirect evidence “CV Therapeutics, Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 2 | 298 contacts → | ||||
Strong evidence “Cleerly is the company on a mission to eliminate heart attacks by creating a new standard of care for the diagnosis of heart disease.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 3 | 189 contacts → | ||||
Partial evidence “Verve Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, is developing a new class of genetic medicines for cardiovascular disease with the potential to transform…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 4 | 119 contacts → | ||||
Partial evidence “Tenaya Therapeutics is a clinical stage biotechnology company.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 5 | 94 contacts → | ||||
Indirect evidence “Building high-performance genetic technologies that transform patient lives.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 6 | 74 contacts → | ||||
Partial evidence “Cardurion Pharmaceuticals is a next generation cardiovascular company focused on the discovery and development of novel therapeutics for the treatment of heart failure and other…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 7 | 73 contacts → | ||||
Partial evidence “Fourth Frontier is a pioneering health tech company that builds and offers products and services for monitoring and improving heart health for people across the world.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 8 | 69 contacts → | ||||
Indirect evidence “We operate with a “No Analog” mindset-continually pushing boundaries, navigating new terrain and unleashing fresh thinking.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 9 | 53 contacts → | ||||
Partial evidence “Avertix is committed to advancing life-sustaining patient care and the long-term management of Advanced Cardiovascular Disease through innovation, clinical science, and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 10 | 32 contacts → | ||||
Partial evidence “Harnessing the power of immunotherapy to develop and deliver transformative medicines for patients with cardiovascular disease” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 11 | 30 contacts → | ||||
Strong evidence “Heart disease is the leading cause of death in the world.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 12 | 30 contacts → | ||||
Indirect evidence “Nuevocor, with offices in USA and Singapore, is developing genetic medicines for untreatable genetic cardiomyopathies by leveraging insights from our PrOSIA mechanobiology…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 13 | 28 contacts → | ||||
Strong evidence “Cardio Diagnostics is a biotechnology company that makes cardiovascular disease prevention and early detection more accessible, personalized, and precise.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 14 | 22 contacts → | ||||
Indirect evidence “HD Medical, Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 15 | 22 contacts → | ||||
Partial evidence “Delivering solutions for Data Driven personalized care for patients with Cardiovascular disease.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 16 | 19 contacts → | ||||
Indirect evidence “T45 Labs is a Silicon Valley-based medtech incubator and investment platform that builds acquisition-ready cardiovascular companies.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 17 | 16 contacts → | ||||
Partial evidence “On a mission to revolutionize structural heart health monitoring in the coming decade; combining biologically inspired hardware and software; with AI and Cloud Computing.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 18 | 14 contacts → | ||||
Partial evidence “Inovise Medical develops technology for heart failure monitoring.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 19 | 13 contacts → | ||||
Partial evidence “RCE.ai, an innovative artificial intelligence (AI) based medical technology company, is dedicated to early heart attack detection.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 20 | 12 contacts → | ||||
Partial evidence “AccuLine is developing CORA, a system to help primary care physicians detect coronary artery disease through a rapid, non-invasive test.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 21 | 12 contacts → | ||||
Partial evidence “SeeMedX is revolutionizing the noninvasive heart monitoring space with its patented technology that can save lives and improve patient outcomes.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 22 | 12 contacts → | ||||
Partial evidence “Vitaliti is a preventive healthtech startup focused on reducing enterprise healthcare costs while improving employee health and productivity.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 23 | 12 contacts → | ||||
Partial evidence “Mawi Heart is a digital health company that revolutionizes the way we diagnose, react and prevent the three largest causes of death in the world: heart failures, heart attacks…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 24 | 11 contacts → | ||||
Indirect evidence “Empowering Healthcare with AI.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 25 | 11 contacts → | ||||
Indirect evidence “CytoHub - Crafting Cells for Cures.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: heart disease biotech startups. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names heart disease biotech startups.
- Partial evidence
- Its own public description names part of heart disease biotech startups, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name heart disease biotech startups. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 100 heart disease biotech startups based in the United States
See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 707 reachable decision-makers.
Free signup · no credit card
Heart disease biotech startups based in the United States at a glance
As of Sep 16, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 100 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among heart disease biotech startups, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “heart disease biotech startups”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names heart disease biotech startups), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among heart disease biotech startups, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 707 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names heart disease biotech startups, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many heart disease biotech startups are there based in the United States?
RevenueBase identified 100 heart disease biotech startups headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
CV Therapeutics, headquartered in Palo Alto, tops this list with the largest team on record.
Which city has the most heart disease biotech startups?
Houston leads with 8 headquartered companies, followed by Boston (3) and Cambridge (3).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 707 verified decision-maker contacts tracked across these 100 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.
Ready to reach these companies? Verified emails and direct dials for all 100 heart disease biotech startups based in the United States. Start with a free account, no credit card.
Download this list →Related lists
Browse the directory
Browse: Companies home · All United States lists · All Heart disease biotech startups lists · New lists
About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
More company lists
- All company lists
- Lists by location
- Lists A-Z
- New lists
- AI companies based in the United States
- Cybersecurity companies based in the United States
- Manufacturing companies based in the United States
- Media companies based in the United States
- Oil and gas companies based in the United States
- Real estate companies based in the United States