Company lists · Data refreshed September 2026

Top 25 Healthcare interoperability software companies based in the United States

Name: Healthcare interoperability software companies based in the United States
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 3, 2026 858 companies tracked

RevenueBase identified 858 healthcare interoperability software companies headquartered in the United States as of September 2026 and tracks 48,191 professional contacts across them, including 19,620 with verified work emails and 17,983 with mobile numbers. New York is the largest hub.

This list covers healthcare interoperability software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 3, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 3, 2026 86% judged on-target in blind review

858Companies

48,191Contacts tracked

19,620Verified emails

17,983Mobile numbers

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The 25 largest healthcare interoperability software companies based in the United States

Ranked by team size

Top 25 of 858 healthcare interoperability software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 3, 2026. RevenueBase Smart Search rates how each company's information relates to healthcare interoperability software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Eclinicalworks	Partial evidence	Westborough, CA, United StatesHQ checked Sep 3, 2026	5,001-10,000	5,251 contacts →
	Partial evidence “eClinicalWorks is a privately held leader in healthcare IT, providing comprehensive Electronic Health Record (EHR) and Practice Management (PM) solutions used by more than medical…” Source: RevenueBase Database · checked Sep 3, 2026
2	Meditech	Partial evidence	Canton, MA, United StatesHQ checked Sep 3, 2026	1,001-5,000	3,400 contacts →
	Partial evidence “MEDITECH empowers healthcare organizations everywhere to expand their vision of what’s possible with Expanse, the world’s most intuitive and interoperable EHR.” Source: RevenueBase Database · checked Sep 3, 2026
3	Datavant	Partial evidence	New York City, NY, United StatesHQ checked Sep 3, 2026	5,001-10,000	2,863 contacts →
	Partial evidence “Datavant is the data collaboration platform trusted for healthcare.” Source: RevenueBase Database · checked Sep 3, 2026
4	Netsmart	Partial evidence	Overland Park, IL, United StatesHQ checked Sep 3, 2026	1,001-5,000	2,457 contacts →
	Partial evidence “Netsmart is an industry-leading healthcare technology organization dedicated to empowering providers to deliver value-based care to individuals and communities.” Source: RevenueBase Database · checked Sep 3, 2026
5	Wellsky	Partial evidence	Overland Park, KS, United StatesHQ checked Sep 3, 2026	1,001-5,000	2,000 contacts →
	Partial evidence “WellSky is one of America’s largest and most innovative healthcare technology companies leading the movement for intelligent, coordinated care.” Source: RevenueBase Database · checked Sep 3, 2026
6	Curemd	Partial evidence	New York, NY, United StatesHQ checked Sep 3, 2026	1,001-5,000	1,713 contacts →
	Partial evidence “Join CureMD – Innovating Healthcare, Empowering People At CureMD, we are at the forefront of healthcare innovation, driven by a passion for creating a better future.” Source: RevenueBase Database · checked Sep 3, 2026
7	Trizetto Healthcare Products	Indirect evidence	Teaneck, CO, United StatesHQ checked Sep 3, 2026	10001+	995 contacts →
	Indirect evidence “Cognizant (Nasdaq-100: CTSH) is one of the world's leading professional services companies, transforming clients' business, operating and technology models for the digital era.” Source: RevenueBase Database · checked Sep 3, 2026
8	Simplify Healthcare	Partial evidence	Aurora, IL, United StatesHQ checked Sep 3, 2026	501-1,000	960 contacts →
	Partial evidence “Healthcare technology company providing cloud-based AI-powered SaaS solutions for health insurance payers.” Source: RevenueBase Database · checked Sep 3, 2026
9	CPSI	Partial evidence	Emanuel, AL, United StatesHQ checked Sep 3, 2026	1,001-5,000	850 contacts →
	Partial evidence “CPSI is a leading provider of healthcare solutions and services for community hospitals, their clinics and post-acute care facilities.” Source: RevenueBase Database · checked Sep 3, 2026
10	Edifecs	Indirect evidence	Bellevue, WA, United StatesHQ checked Sep 3, 2026	1,001-5,000	808 contacts →
	Indirect evidence “Edifecs, a Cotiviti business, provides market-leading technology to its payer and health system customers, which serve nearly 300 million people in the U.S.” Source: RevenueBase Database · checked Sep 3, 2026
11	Surescripts	Partial evidence	Arlington, NC, United StatesHQ checked Sep 3, 2026	501-1,000	712 contacts →
	Partial evidence “At Surescripts, we bring healthcare together to inform and accelerate decisions, helping keep patient care on track.” Source: RevenueBase Database · checked Sep 3, 2026
12	Meditab Software INC	Partial evidence	Sacramento, CA, United StatesHQ checked Sep 3, 2026	201-500	690 contacts →
	Partial evidence “Empowering our clients with cutting edge technology to meet future healthcare needs today.” Source: RevenueBase Database · checked Sep 3, 2026
13	Mckesson Health Solutions	Partial evidence	Nashville, TN, United StatesHQ checked Sep 3, 2026	10001+	683 contacts →
	Partial evidence “Change Healthcare is inspiring a better healthcare system.” Source: RevenueBase Database · checked Sep 3, 2026
14	Healthport Technologies	Indirect evidence	Alpharetta, GA, United StatesHQ checked Sep 3, 2026	5,001-10,000	653 contacts →
	Indirect evidence “HealthPort Technologies is now CIOX Health.” Source: RevenueBase Database · checked Sep 3, 2026
15	Centauri Health Solutions, INC	Indirect evidence	Tempe, OH, United StatesHQ checked Sep 3, 2026	1,001-5,000	609 contacts →
	Indirect evidence “Centauri Health Solutions aims to attract and retain the industry’s top talent as we continue to create and deliver the most flexible and innovative tools in the market.” Source: RevenueBase Database · checked Sep 3, 2026
16	Ellkay	Partial evidence	Elmwood Park, NJ, United StatesHQ checked Sep 3, 2026	501-1,000	577 contacts →
	Partial evidence “ELLKAY is a trusted enterprise data management partner, driving innovation and connectivity across the healthcare ecosystem.” Source: RevenueBase Database · checked Sep 3, 2026
17	Verisma	Partial evidence	Alpharetta, CO, United StatesHQ checked Sep 3, 2026	1,001-5,000	546 contacts →
	Partial evidence “Verisma, trusted by clients across 50 states, is redefining how healthcare organizations manage and use health data – ensuring it’s trusted, secure and actionable for real-time…” Source: RevenueBase Database · checked Sep 3, 2026
18	Smart Data Solutions	Partial evidence	Eagan, MN, United StatesHQ checked Sep 3, 2026	501-1,000	446 contacts →
	Partial evidence “Smart Data Solutions is a healthcare technology company helping health plans, healthcare payers, and third-party administrators (TPAs) automate complex operational workflows…” Source: RevenueBase Database · checked Sep 3, 2026
19	Compugroup Medical US	Partial evidence	Richardson, TX, United StatesHQ checked Sep 3, 2026	5,001-10,000	319 contacts →
	Partial evidence “CompuGroup Medical is a global e-health provider with a comprehensive portfolio of cutting-edge IT solutions for the healthcare industry.” Source: RevenueBase Database · checked Sep 3, 2026
20	Rhapsody	Strong evidence	Boston, MA, United StatesHQ checked Sep 3, 2026	201-500	313 contacts →
	Strong evidence “Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: RevenueBase Database · checked Sep 3, 2026
21	Ehealth Technologies	Partial evidence	Fairport, PA, United StatesHQ checked Sep 3, 2026	501-1,000	303 contacts →
	Partial evidence “Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: RevenueBase Database · checked Sep 3, 2026
22	Abacus Insights	Partial evidence	Boston, MA, United StatesHQ checked Sep 3, 2026	201-500	289 contacts →
	Partial evidence “Abacus Insights is a healthcare technology leader with the only data usability platform and solutions built specifically for U.S.” Source: RevenueBase Database · checked Sep 3, 2026
23	314e Corporation	Partial evidence	Dublin, CA, United StatesHQ checked Sep 3, 2026	501-1,000	276 contacts →
	Partial evidence “314e is a Best in KLAS Healthcare IT Products and Solutions company, serving 250+ Providers, Payers, and Life Sciences companies.” Source: RevenueBase Database · checked Sep 3, 2026
24	DAS Health	Partial evidence	Tampa, TX, United StatesHQ checked Sep 3, 2026	201-500	273 contacts →
	Partial evidence “DAS Health delivers the highest value Health IT and Business Solutions for healthcare organizations all over the country.” Source: RevenueBase Database · checked Sep 3, 2026
25	Regenstrief Institute, INC	Indirect evidence	Indianapolis, IN, United StatesHQ checked Sep 3, 2026	201-500	233 contacts →
	Indirect evidence “Regenstrief Institute, Inc, an international leader in electronic medical records and health care data integration, is a medical research and development organization focused on…” Source: RevenueBase Database · checked Sep 3, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: healthcare interoperability software companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names healthcare interoperability software companies.
Partial evidence: Its own public description names part of healthcare interoperability software companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name healthcare interoperability software companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 858 healthcare interoperability software companies based in the United States

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Healthcare interoperability software companies based in the United States at a glance

As of Sep 3, 2026

40.7%Verified-email coverage

37.3%Mobile-number coverage

56.2Average contacts per company

11-50Median size (employees)

3.3%Largest-city concentration · New York

Sep 3, 2026Page data refreshed

Companies by employee count

1-10

277

11-50

362

51-200

151

201-500

501-1,000

1,001-5,000

5,001-10,000

10001+

Freshness & accuracy

How recently the business emails on this list were verified

Email last verified

00–30

1,63631–60

11,08461–90

6,73990–180

161180+

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among healthcare interoperability software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in the United States whose own description of what they do matches “healthcare interoperability software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names healthcare interoperability software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among healthcare interoperability software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 19,620 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 3, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names healthcare interoperability software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many healthcare interoperability software companies are there based in the United States?

RevenueBase identified 858 healthcare interoperability software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Eclinicalworks, headquartered in Pleasanton, tops this list with the largest team on record.

Which city has the most healthcare interoperability software companies?

New York leads with 28 headquartered companies, followed by San Francisco (15) and Austin (14).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 19,620 verified decision-maker contacts tracked across these 858 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 3, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.