Company lists · Data refreshed September 2026

Top 24 Healthcare enterprise software companies based in South Africa

Name: Healthcare enterprise software companies based in South Africa
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 28, 2026 65 companies tracked

RevenueBase identified 65 healthcare enterprise software companies headquartered in South Africa as of September 2026 and tracks 1,382 professional contacts across them, including 425 with verified work emails. Johannesburg is the largest hub.

This list covers healthcare enterprise software companies headquartered in South Africa, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 28, 2026 86% judged on-target in blind review

65Companies

1,382Contacts tracked

425Verified emails

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The 24 largest healthcare enterprise software companies based in South Africa

Ranked by team size

Top 24 of 65 healthcare enterprise software companies based in South Africa, ranked by team size, largest first. Data refreshed Sep 28, 2026. RevenueBase Smart Search rates how each company's information relates to healthcare enterprise software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Healthbridge	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	51-200	252 contacts →
	Partial evidence “Our comprehensive suite of solutions includes medical billing and clinical software, bureau services, and value-added services that free up valuable time for practitioners to…” Source: RevenueBase Database · checked Sep 28, 2026
2	Medikredit Integrated Healthcare Solutions	Indirect evidence	Sandton, South AfricaHQ checked Sep 28, 2026	201-500	215 contacts →
	Indirect evidence “With a proud track record of over 80 years, MediKredit remains the pioneer in smart technology services – from pharmacy benefit management to claims processing, data analysis and…” Source: RevenueBase Database · checked Sep 28, 2026
3	First Care Solutions	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	51-200	79 contacts →
	Indirect evidence “First Care Solutions is a medical administration and services company founded in 2007.” Source: RevenueBase Database · checked Sep 28, 2026
4	Compugroup Medical South Africa	Indirect evidence	Century City, South AfricaHQ checked Sep 28, 2026	51-200	51 contacts →
	Indirect evidence “CGM recognises the extra in the ordinary; the little things that transform the ordinary into something remarkable.” Source: RevenueBase Database · checked Sep 28, 2026
5	Spesnet Group	Partial evidence	Centurion, South AfricaHQ checked Sep 28, 2026	51-200	37 contacts →
	Partial evidence “At SpesNet, we're at the forefront of healthcare solutions for providers, insurers, administrators, and managed care organisations.” Source: RevenueBase Database · checked Sep 28, 2026
6	Lifesense	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	51-200	35 contacts →
	Partial evidence “LifeSense Group specialises in Healthcare service provision, specifically relating to Chronic Disease Management and Employee Wellness programmes.” Source: RevenueBase Database · checked Sep 28, 2026
7	Allegra Healthcare Management Solutions	Partial evidence	Pretoria, South AfricaHQ checked Sep 28, 2026	51-200	33 contacts →
	Partial evidence “At Allegra, we believe in the power of technology to improve efficiencies for healthcare providers.” Source: RevenueBase Database · checked Sep 28, 2026
8	Trifour	Partial evidence	Pretoria, South AfricaHQ checked Sep 28, 2026	51-200	25 contacts →
	Partial evidence “TriFour provides specialist Information Technology (IT) solutions and services to the healthcare market that improves patient outcomes and enhances cash flows.” Source: RevenueBase Database · checked Sep 28, 2026
9	Prime Medical Casualty Group	Partial evidence	Springs, South AfricaHQ checked Sep 28, 2026	11-50	13 contacts →
	Partial evidence “Emergency department management company, focused on the implementation of technology and innovation to improve the delivery of healthcare to patients.” Source: RevenueBase Database · checked Sep 28, 2026
10	Vertice Mobile Healthcare	Partial evidence	Pretoria, South AfricaHQ checked Sep 28, 2026	11-50	12 contacts →
	Partial evidence “Vertice Mobile Healthcare is a leading provider of comprehensive healthcare solutions, serving both public and private sectors with a focus on radiology, mobile and alternative…” Source: RevenueBase Database · checked Sep 28, 2026
11	Medicalrcs	Partial evidence	City Of Tshwane, South AfricaHQ checked Sep 28, 2026	1-10	10 contacts →
	Partial evidence “Medical RCS is a user-friendly cloud-based practice management software for medical practitioners and patients.” Source: RevenueBase Database · checked Sep 28, 2026
12	Medical EDI Services PTY LTD	Partial evidence	Margate, South AfricaHQ checked Sep 28, 2026	51-200	10 contacts →
	Partial evidence “The founders of Medical EDI Services have been developing medical billing and practice management software for the medical fraternity for the past twenty years.” Source: RevenueBase Database · checked Sep 28, 2026
13	Lifechoice	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	1-10	9 contacts →
	Partial evidence “Lifechoice is a business intelligence and clinical data warehousing consultancy established by health and technology professionals with the aim of improving healthcare in South…” Source: RevenueBase Database · checked Sep 28, 2026
14	Bookem	Strong evidence	Hout Bay, South AfricaHQ checked Sep 28, 2026	1-10	7 contacts →
	Strong evidence “Boost Your Medical Practice Efficiency and Online Visibility with Bookem’s All-in-One Integrated Healthcare Solution Bookem’s practice management and EHR software streamlines…” Source: RevenueBase Database · checked Sep 28, 2026
15	Evolve Medical Software Solutions	Indirect evidence	Centurion, South AfricaHQ checked Sep 28, 2026	51-200	7 contacts →
	Indirect evidence “Brand Our philosophy is to provide systems and service which exceed the requirements of our clients and their customers, enabling them to operate efficiently and successfully.” Source: RevenueBase Database · checked Sep 28, 2026
16	Healthcare Framework	Strong evidence	Pretoria, South AfricaHQ checked Sep 28, 2026	11-50	7 contacts →
	Strong evidence “Healthcare Framework HCF is a cloud-based healthcare software application which is used to capture clinical data, manage patient workflow, electronic medical records (EMR) and…” Source: RevenueBase Database · checked Sep 28, 2026
17	Healthware	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	1-10	6 contacts →
	Partial evidence “HealthWare Medical Technology provides a complete software solution to manage the clinical, administrative and financial requirements of any care home facility or hospital.” Source: RevenueBase Database · checked Sep 28, 2026
18	Kitrin	Partial evidence	Fourways, South AfricaHQ checked Sep 28, 2026	1-10	5 contacts →
	Partial evidence “KITRIN is a company focused on assisting business owners, including healthcare practitioners in private practice, with their operational business functions so that they can…” Source: RevenueBase Database · checked Sep 28, 2026
19	Mamello Clinical Solutions	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	5 contacts →
	Partial evidence “Founded in 2014, Mamello Clinical Solutions aims to be the most integrated, reliable and customer-driven healthcare solutions provider in South Africa.” Source: RevenueBase Database · checked Sep 28, 2026
20	Stethoscope SA	Indirect evidence	Somerset West, South AfricaHQ checked Sep 28, 2026	1-10	5 contacts →
	Indirect evidence “At Stethoscope, our focus is to revolutionize medical administration through effective management and automation.” Source: RevenueBase Database · checked Sep 28, 2026
21	Digidata	Strong evidence	Pretoria, South AfricaHQ checked Sep 28, 2026	11-50	4 contacts →
	Strong evidence “Our primary focus is to develop, deploy and support software in the healthcare industry.” Source: RevenueBase Database · checked Sep 28, 2026
22	Ikat G3 Medical Practice Software	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	3 contacts →
	Partial evidence “IKAT G3 Advanced PMA Software is dedicated to helping medical practitioners transform their administration into an efficient and profitable business process.” Source: RevenueBase Database · checked Sep 28, 2026
23	ZTI Health And Technology	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	2 contacts →
	Indirect evidence “Welcome to ZTI Health & Technology - Your Partner in Process Engineering and Health Tech Solutions ZTI Health & Technology is your premier destination for innovative Process…” Source: RevenueBase Database · checked Sep 28, 2026
24	Hugo Systems	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	1-10	1 contacts →
	Indirect evidence “Hugo Systems develops and implements medical systems to assist with the streamlining and automation of tasks within medical practices.” Source: RevenueBase Database · checked Sep 28, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: healthcare enterprise software companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names healthcare enterprise software companies.
Partial evidence: Its own public description names part of healthcare enterprise software companies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name healthcare enterprise software companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 24 of 65 healthcare enterprise software companies based in South Africa

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Healthcare enterprise software companies based in South Africa at a glance

As of Sep 28, 2026

30.8%Verified-email coverage

21.3Average contacts per company

11-50Median size (employees)

24.6%Largest-city concentration · Johannesburg

Sep 28, 2026Page data refreshed

Companies by employee count

1-10

11-50

51-200

201-500

Email recency for this list is measured worldwide rather than for South Africa, so it is reported there. Company counts and contact totals on this page are exact for South Africa, over 65 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among healthcare enterprise software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in South Africa whose own description of what they do matches “healthcare enterprise software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names healthcare enterprise software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among healthcare enterprise software companies, and records with no verified work email. Companies headquartered outside South Africa are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 425 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names healthcare enterprise software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many healthcare enterprise software companies are there based in South Africa?

RevenueBase identified 65 healthcare enterprise software companies headquartered in South Africa as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Healthbridge, headquartered in Johannesburg, tops this list with the largest team on record.

Which city has the most healthcare enterprise software companies?

Johannesburg leads with 16 headquartered companies, followed by Cape Town (9) and Pretoria (7).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 425 verified decision-maker contacts tracked across these 65 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.