Company lists · Data refreshed September 2026

Top 25 Healthcare creative agencies based in South Africa

Name: Healthcare creative agencies based in South Africa
Creator: RevenueBase
License: https://creativecommons.org/licenses/by/4.0/

Compiled by the RevenueBase Data Team Data refreshed Sep 28, 2026 313 companies tracked

RevenueBase identified 313 healthcare creative agencies headquartered in South Africa as of September 2026 and tracks 1,689 professional contacts across them, including 447 with verified work emails. Johannesburg is the largest hub.

This list covers healthcare creative agencies headquartered in South Africa, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 28, 2026 86% judged on-target in blind review

313Companies

1,689Contacts tracked

447Verified emails

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The 25 largest healthcare creative agencies based in South Africa

Ranked by team size

Top 25 of 313 healthcare creative agencies based in South Africa, ranked by team size, largest first. Data refreshed Sep 28, 2026. RevenueBase Smart Search rates how each company's information relates to healthcare creative agencies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#	Company	RevenueBase Smart Search	Headquarters	Employees	Contacts
1	Charisma Healthcare Solutions	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	501-1,000	133 contacts →
	Indirect evidence “Founded in 1992, Charisma!” Source: RevenueBase Database · checked Sep 28, 2026
2	Røering Creative KIN	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	51-200	64 contacts →
	Indirect evidence “Level 1 B-BBEE status holder as a large entity.” Source: RevenueBase Database · checked Sep 28, 2026
3	The Onshelf Group	Indirect evidence	Centurion, South AfricaHQ checked Sep 28, 2026	201-500	62 contacts →
	Indirect evidence “OnShelf Pharma is a Fast Moving Health Care Sales, Distribution and Merchandising Agency.” Source: RevenueBase Database · checked Sep 28, 2026
4	Hamiltons Advertising	Partial evidence	Brackenfell, South AfricaHQ checked Sep 28, 2026	11-50	54 contacts →
	Partial evidence “Hamiltons in Creative is a marketing and advertising company based out of Unit 25, Cornerstone Business Park, 24 London Circle, Brackengate Business Park.” Source: RevenueBase Database · checked Sep 28, 2026
5	DNA Brand Architects	Indirect evidence	Fourways, South AfricaHQ checked Sep 28, 2026	51-200	40 contacts →
	Indirect evidence “The journey of an independent agency is seldom easy; it's a path where only the resilient thrive, and for 12 glorious years, we have done just that.” Source: RevenueBase Database · checked Sep 28, 2026
6	Retroviral	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	35 contacts →
	Indirect evidence “We have a challenger mindset and through this have made more brands ‘go viral’, globally, than any other agency in Africa.” Source: RevenueBase Database · checked Sep 28, 2026
7	Lkda Strategic Creative Advertising	Partial evidence	Irene, South AfricaHQ checked Sep 28, 2026	11-50	32 contacts →
	Partial evidence “LKDA is a dynamic and strategically driven creative agency with the core focus of assisting in the growth of our clients through powerful, insightful and innovative communication…” Source: RevenueBase Database · checked Sep 28, 2026
8	WWP Group	Partial evidence	Lonehill, South AfricaHQ checked Sep 28, 2026	11-50	32 contacts →
	Partial evidence “We are a young & dynamic strategic creative agency, founded on the core values of visual and experiential storytelling, meticulous planning and flawless execution.” Source: RevenueBase Database · checked Sep 28, 2026
9	Halo Advertising	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	31 contacts →
	Indirect evidence “Halo.” Source: RevenueBase Database · checked Sep 28, 2026
10	Happy Friday Creative	Partial evidence	Century City, South AfricaHQ checked Sep 28, 2026	11-50	21 contacts →
	Partial evidence “Say hello to Happy Friday, a new people-centric creative agency obsessed with crafting creative advertising that makes our clients deliriously happy.” Source: RevenueBase Database · checked Sep 28, 2026
11	Motsepe Advertising	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	1-10	21 contacts →
	Indirect evidence “We turn advertising into compelling storytelling to connect our clients with their consumers.” Source: RevenueBase Database · checked Sep 28, 2026
12	Lesoba Difference	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	19 contacts →
	Indirect evidence “Lesoba Difference isn’t just another agency -we’re the award-winning team behind campaigns that have turned brands into household names.” Source: RevenueBase Database · checked Sep 28, 2026
13	Fishgate Advertising	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	11-50	19 contacts →
	Partial evidence “We are a creative agency that specializes in problem-solving for our clients' communication needs, guiding brands from the initial stages of logo development to the rollout and…” Source: RevenueBase Database · checked Sep 28, 2026
14	Full Circle Agency	Indirect evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	11-50	17 contacts →
	Indirect evidence “We are a full service, high energy, bold and curious marketing agency who offers a collaborative way of working.” Source: RevenueBase Database · checked Sep 28, 2026
15	Soulproviders Collective	Indirect evidence	Bryanston, South AfricaHQ checked Sep 28, 2026	11-50	17 contacts →
	Indirect evidence “We’re an edgy alternative to traditional advertising.” Source: RevenueBase Database · checked Sep 28, 2026
16	SHIFT	Indirect evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	16 contacts →
	Indirect evidence “Through unrestrained, diverse, brand-led thinking, we create authentic connections that bring you closer to your audience.” Source: RevenueBase Database · checked Sep 28, 2026
17	Just Brands Africa	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	11-50	14 contacts →
	Partial evidence “Just Brands Africa was founded in 2013 with one goal in mind, to develop magical creative experiences for brands.” Source: RevenueBase Database · checked Sep 28, 2026
18	Octane Marketing	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	11-50	14 contacts →
	Partial evidence “Octane Marketing is a full-throttle, insight-driven creative engine built for brands that want to move faster, think smarter and show up boldly in every channel that matters.” Source: RevenueBase Database · checked Sep 28, 2026
19	Holycow Creative Agency	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	14 contacts →
	Partial evidence “Holy Cow is a strategic creative agency that uses animation, video and visual storytelling to solve business problems.” Source: RevenueBase Database · checked Sep 28, 2026
20	Felix Studios PTY LTD	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	1-10	13 contacts →
	Partial evidence “Felix Studios is a creative agency that services clients from leading brands around the world in industries including luxury travel, technology, automotive, online learning, fine…” Source: RevenueBase Database · checked Sep 28, 2026
21	Creative & Stuff	Partial evidence	Sandton, South AfricaHQ checked Sep 28, 2026	11-50	11 contacts →
	Partial evidence “We’re not your typical agency-we’re a lean, mean (but super friendly) creative machine.” Source: RevenueBase Database · checked Sep 28, 2026
22	Blue Apple South Africa	Partial evidence	Johannesburg, South AfricaHQ checked Sep 28, 2026	11-50	10 contacts →
	Partial evidence “Welcome to the no-hot-air, low-maintenance creative agency that delivers the goods, smartly.” Source: RevenueBase Database · checked Sep 28, 2026
23	The Fire Tree Design Company PTY LTD	Partial evidence	Durban, South AfricaHQ checked Sep 28, 2026	11-50	10 contacts →
	Partial evidence “Advertising, Print & Signage, Social Media, Photography & Brand Development - Fire Tree's soul purpose as a marketing agency is to use our creativity and expertise to light your…” Source: RevenueBase Database · checked Sep 28, 2026
24	Reload	Partial evidence	Cape Town, South AfricaHQ checked Sep 28, 2026	11-50	10 contacts →
	Partial evidence “A BOUTIQUE CREATIVE AGENCY SERVING CLIENTS IN SOUTH AFRICA, THE UK, AND THE USA You are a marketing expert.” Source: RevenueBase Database · checked Sep 28, 2026
25	4time Creatives	Indirect evidence	City Of Tshwane, South AfricaHQ checked Sep 28, 2026	1-10	9 contacts →
	Indirect evidence “We create bold brands online.” Source: RevenueBase Database · checked Sep 28, 2026

RevenueBase Smart Search

RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: healthcare creative agencies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.

Strong evidence: The company's own public description of its business names healthcare creative agencies.
Partial evidence: Its own public description names part of healthcare creative agencies, so it works in or next to the category without describing itself that way.
Indirect evidence: The description shown does not name healthcare creative agencies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.

RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.

Showing 25 of 313 healthcare creative agencies based in South Africa

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Healthcare creative agencies based in South Africa at a glance

As of Sep 28, 2026

26.5%Verified-email coverage

5.4Average contacts per company

1-10Median size (employees)

31.6%Largest-city concentration · Johannesburg

Sep 28, 2026Page data refreshed

Companies by employee count

1-10

228

11-50

51-200

201-500

501-1,000

Email recency for this list is measured worldwide rather than for South Africa, so it is reported there. Company counts and contact totals on this page are exact for South Africa, over 313 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among healthcare creative agencies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source: The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies: Companies headquartered in South Africa whose own description of what they do matches “healthcare creative agencies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search: RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names healthcare creative agencies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude: Companies whose own description does not clearly place them among healthcare creative agencies, and records with no verified work email. Companies headquartered outside South Africa are excluded even when they keep an office there.
Match quality: In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking: Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification: Every listed company carries at least one verified work email, 447 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh: This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Corrections: Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Healthcare creative agencies by metro

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names healthcare creative agencies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many healthcare creative agencies are there based in South Africa?

RevenueBase identified 313 healthcare creative agencies headquartered in South Africa as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Charisma Healthcare Solutions, headquartered in Johannesburg, tops this list with the largest team on record.

Which city has the most healthcare creative agencies?

Johannesburg leads with 99 headquartered companies, followed by Cape Town (60) and Pretoria (21).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 447 verified decision-maker contacts tracked across these 313 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.