Company lists · Data refreshed September 2026
Top 25 Health information exchanges based in the United States
RevenueBase identified 183 health information exchanges headquartered in the United States as of September 2026 and tracks 10,241 professional contacts across them, including 5,304 with verified work emails. Columbia is the largest hub.
This list covers health information exchanges headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 20, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest health information exchanges based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 2,839 contacts → | ||||
Partial evidence “Datavant is the data collaboration platform trusted for healthcare.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 2 | 1,722 contacts → | ||||
Partial evidence “Availity is the place where healthcare finds the answers needed to shift focus back to patient care.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 3 | 706 contacts → | ||||
Partial evidence “At Surescripts, we bring healthcare together to inform and accelerate decisions, helping keep patient care on track.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 4 | 651 contacts → | ||||
Partial evidence “HealthPort Technologies is now CIOX Health.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 5 | 314 contacts → | ||||
Partial evidence “Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 6 | 306 contacts → | ||||
Partial evidence “Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 7 | 179 contacts → | ||||
Strong evidence “Michigan Health Information Network Shared Services (MiHIN) is the statewide health information exchange, dedicated to transforming healthcare by connecting the right data to the…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 8 | 141 contacts → | ||||
Strong evidence “Redox helps providers, payers, health tech vendors, EHRs, and Life Sciences power better care with real-time data exchange.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 9 | 120 contacts → | ||||
Partial evidence “AaNeel is a healthcare interoperability platform built for payers and value-based care organizations.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 10 | 117 contacts → | ||||
Strong evidence “Lantana Consulting Group provides services and software solutions for standards-based health information exchange.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 11 | 109 contacts → | ||||
Partial evidence “Health Gorilla, a designated QHIN under TEFCA, is a leading provider of interoperability solutions delivering secure, real-time access to structured, AI-ready health data.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 12 | 95 contacts → | ||||
Strong evidence “The Indiana Health Information Exchange is the largest health information exchange network in the U.S, partnering with communities throughout Indiana to ensure health information…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 13 | 94 contacts → | ||||
Strong evidence “The Ohio Health Information Partnership is a non-profit entity whose mission is to assist physicians and other providers with the adoption and implement of health information…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 14 | 87 contacts → | ||||
Partial evidence “Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 15 | 84 contacts → | ||||
Strong evidence “CRISP is a regional health information exchange (HIE) serving Maryland and the District of Columbia.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 16 | 84 contacts → | ||||
Partial evidence “HEALTHeLINK™ serves as a resource for broad health system transformation through secure data-informed decision making for individual patient care and to support community…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 17 | 81 contacts → | ||||
Strong evidence “Healthix is the largest public Health Information Exchange (HIE) in the nation, serving New York City and Long Island.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 18 | 80 contacts → | ||||
Partial evidence “The Network Where Healthcare Connects.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 19 | 76 contacts → | ||||
Indirect evidence “Formed in 2004, Ruvos is on a mission to deliver clever and efficient solutions to problems so that the world is a better place for the communities we serve.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 20 | 75 contacts → | ||||
Partial evidence “Moxe connects the healthcare ecosystem with high quality, meaningful data to drive better outcomes.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 21 | 69 contacts → | ||||
Partial evidence “Update: DataFile Technologies was acquired by ScanSTAT Technologies in April 2020, creating the largest founder-owned Release of Information and HIM company in the country.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 22 | 68 contacts → | ||||
Strong evidence “Manifest MedEx is California’s largest nonprofit health data network, powering the high-resolution, whole person data exchange needed to optimize health.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 23 | 66 contacts → | ||||
Partial evidence “New York eHealth Collaborative (NYeC, pronounced “nice”) is a non-profit organization working in partnership with the New York State Department of Health to improve healthcare…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 24 | 61 contacts → | ||||
Strong evidence “We created the first federated health information network: a powerful platform that connects disparate data silos through a single interface.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 25 | 58 contacts → | ||||
Strong evidence “In 2007 the Delaware Health Information Network (DHIN) became the first live, statewide health information network in the nation.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: health information exchanges. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names health information exchanges.
- Partial evidence
- Its own public description names part of health information exchanges, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name health information exchanges. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 183 health information exchanges based in the United States
See the full list, filter by size, metro and specialty, and get verified emails and direct dials for all 5,304 reachable decision-makers.
Free signup · no credit card
Health information exchanges based in the United States at a glance
As of Sep 20, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 183 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among health information exchanges, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “health information exchanges”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names health information exchanges), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among health information exchanges, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 5,304 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names health information exchanges, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many health information exchanges are there based in the United States?
RevenueBase identified 183 health information exchanges headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Datavant, headquartered in New York City, tops this list with the largest team on record.
Which city has the most health information exchanges?
Columbia leads with 7 headquartered companies, followed by Austin (6) and New York (5).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 5,304 verified decision-maker contacts tracked across these 183 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.
Ready to reach these companies? Verified emails and direct dials for all 183 health information exchanges based in the United States. Start with a free account, no credit card.
Download this list →Related lists
About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
More company lists
- All company lists
- Lists by location
- Lists A-Z
- New lists
- AI companies based in the United States
- Cybersecurity companies based in the United States
- Manufacturing companies based in the United States
- Media companies based in the United States
- Oil and gas companies based in the United States
- Real estate companies based in the United States