Company lists · Data refreshed September 2026
Top 25 Health information exchange software companies based in the United States
RevenueBase identified 319 health information exchange software companies headquartered in the United States as of September 2026 and tracks 25,412 professional contacts across them, including 12,732 with verified work emails and 9,337 with mobile numbers. New York is the largest hub.
This list covers health information exchange software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, how directly it supports the match, and when it was last checked. Data refreshed September 3, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase SmartSearch, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest health information exchange software companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 5,251 | ||||
“eClinicalWorks is a privately held leader in healthcare IT, providing comprehensive Electronic Health Record (EHR) and Practice Management (PM) solutions used by more than medical…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 2 | 3,400 | ||||
“MEDITECH empowers healthcare organizations everywhere to expand their vision of what’s possible with Expanse, the world’s most intuitive and interoperable EHR.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 3 | 2,863 | ||||
“Datavant is the data collaboration platform trusted for healthcare.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 4 | 2,457 | ||||
“Netsmart is an industry-leading healthcare technology organization dedicated to empowering providers to deliver value-based care to individuals and communities.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 5 | 1,713 | ||||
“Join CureMD – Innovating Healthcare, Empowering People At CureMD, we are at the forefront of healthcare innovation, driven by a passion for creating a better future.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 6 | 850 | ||||
“CPSI is a leading provider of healthcare solutions and services for community hospitals, their clinics and post-acute care facilities.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 7 | 712 | ||||
“At Surescripts, we bring healthcare together to inform and accelerate decisions, helping keep patient care on track.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 8 | 653 | ||||
“HealthPort Technologies is now CIOX Health.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 9 | 577 | ||||
“ELLKAY is a trusted enterprise data management partner, driving innovation and connectivity across the healthcare ecosystem.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 10 | 517 | ||||
“HealthMark Group is a leading provider of digital health information management solutions for healthcare providers across the country.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 11 | 313 | ||||
“Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 12 | 303 | ||||
“Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 13 | Michigan Health Information Network Shared Services MihinStrong evidence | 177 | |||
“Michigan Health Information Network Shared Services (MiHIN) is the statewide health information exchange, dedicated to transforming healthcare by connecting the right data to the…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 14 | 161 | ||||
“iatricSystems is a healthcare technology company dedicated to helping healthcare organizations enhance their IT investments.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 15 | REDOXStrong evidence | 159 | |||
“Redox helps providers, payers, health tech vendors, EHRs, and Life Sciences power better care with real-time data exchange.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 16 | 137 | ||||
“It’s time to reimagine what’s possible in healthcare.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 17 | 132 | ||||
Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 18 | 128 | ||||
“Oracle has been a leader in life sciences for more than 40 years, igniting innovation through powerful and connected research, data, and technology.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 19 | Medical Informatics EngineeringIndirect evidence | 123 | |||
“Long before they were buzzwords, market segments or government incentive programs, concepts like interoperability, data liquidity, patient engagement and meaningful use were…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 20 | 117 | ||||
“Lantana Consulting Group provides services and software solutions for standards-based health information exchange.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 21 | 106 | ||||
“Health Gorilla, a designated QHIN under TEFCA, is a leading provider of interoperability solutions delivering secure, real-time access to structured, AI-ready health data.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 22 | 95 | ||||
“The Indiana Health Information Exchange is the largest health information exchange network in the U.S, partnering with communities throughout Indiana to ensure health information…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 23 | ZUS HealthPartial evidence | 89 | |||
“Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded…” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 24 | 83 | ||||
“CRISP is a regional health information exchange (HIE) serving Maryland and the District of Columbia.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
| 25 | LeadingreachPartial evidence | 81 | |||
“The Network Where Healthcare Connects.” Source: company website · checked Sep 3, 2026Thanks. The Data Team will review it. | |||||
Showing 25 of 319 health information exchange software companies based in the United States
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Health information exchange software companies based in the United States at a glance
As of Sep 3, 2026Companies by employee count
Verified emails by last verification
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among health information exchange software companies, so some rows will be adjacent to the category rather than pure plays. The description and evidence rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase SmartSearch, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “health information exchange software companies”. Matching reads each company's description, not its industry code or its name.
- What we exclude
- Companies whose own description does not clearly place them among health information exchange software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and an evidence rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 12,732 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 3, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
How many health information exchange software companies are there based in the United States?
RevenueBase identified 319 health information exchange software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Eclinicalworks, headquartered in Pleasanton, tops this list with the largest team on record.
Which city has the most health information exchange software companies?
New York leads with 10 headquartered companies, followed by Atlanta (8) and San Francisco (7).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 12,732 verified decision-maker contacts tracked across these 319 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 3, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase SmartSearch, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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