Company lists · Data refreshed September 2026
Top 25 Health information exchange companies based in the United States
RevenueBase identified 349 health information exchange companies headquartered in the United States as of September 2026 and tracks 15,041 professional contacts across them, including 7,242 with verified work emails. New York is the largest hub.
This list covers health information exchange companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 20, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest health information exchange companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 2,839 contacts → | ||||
Partial evidence “Datavant is the data collaboration platform trusted for healthcare.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 2 | 1,722 contacts → | ||||
Partial evidence “Availity is the place where healthcare finds the answers needed to shift focus back to patient care.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 3 | 706 contacts → | ||||
Partial evidence “At Surescripts, we bring healthcare together to inform and accelerate decisions, helping keep patient care on track.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 4 | 651 contacts → | ||||
Partial evidence “HealthPort Technologies is now CIOX Health.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 5 | 585 contacts → | ||||
Partial evidence “ELLKAY is a trusted enterprise data management partner, driving innovation and connectivity across the healthcare ecosystem.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 6 | 546 contacts → | ||||
Partial evidence “Verisma, trusted by clients across 50 states, is redefining how healthcare organizations manage and use health data – ensuring it’s trusted, secure and actionable for real-time…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 7 | 314 contacts → | ||||
Partial evidence “Rhapsody provides healthcare organizations with infrastructure for agent-ready interoperability so you can connect systems, reduce integration burden, and prepare your data for…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 8 | 306 contacts → | ||||
Partial evidence “Since 2006, eHealth Technologies has helped healthcare organizations close the time-to-treatment gap by delivering timely, organized, clinically relevant, specialty-specific…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 9 | 198 contacts → | ||||
Indirect evidence “In April 2023, ScanSTAT was acquired by Verisma to create a new market leader.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 10 | 192 contacts → | ||||
Strong evidence “Vyne Dental is part of the Vyne family of industry-leading information exchange, revenue acceleration and communication solutions for healthcare.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 11 | 190 contacts → | ||||
Partial evidence “For more than 25 years, CAQH supported the industry with the largest and most complete healthcare data foundation in the U.S.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 12 | 184 contacts → | ||||
Partial evidence “Connecting patients, providers, and healthcare organizations to improve lives through service and technology.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 13 | 179 contacts → | ||||
Strong evidence “Michigan Health Information Network Shared Services (MiHIN) is the statewide health information exchange, dedicated to transforming healthcare by connecting the right data to the…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 14 | 179 contacts → | ||||
Partial evidence “Our secure, scalable solutions provide critical information in a timely manner, positively impacting member outcomes while reducing administrative costs.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 15 | 141 contacts → | ||||
Strong evidence “Redox helps providers, payers, health tech vendors, EHRs, and Life Sciences power better care with real-time data exchange.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 16 | 133 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 17 | 128 contacts → | ||||
Indirect evidence “Oracle has been a leader in life sciences for more than 40 years, igniting innovation through powerful and connected research, data, and technology.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 18 | 120 contacts → | ||||
Partial evidence “AaNeel is a healthcare interoperability platform built for payers and value-based care organizations.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 19 | 117 contacts → | ||||
Strong evidence “Lantana Consulting Group provides services and software solutions for standards-based health information exchange.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 20 | 109 contacts → | ||||
Partial evidence “Health Gorilla, a designated QHIN under TEFCA, is a leading provider of interoperability solutions delivering secure, real-time access to structured, AI-ready health data.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 21 | 100 contacts → | ||||
Partial evidence “Founded in 1987, Health Level Seven (HL7) is an ANSI-accredited non-profit that empowers global health data interoperability by developing standards and enabling their adoption…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 22 | 95 contacts → | ||||
Strong evidence “The Indiana Health Information Exchange is the largest health information exchange network in the U.S, partnering with communities throughout Indiana to ensure health information…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 23 | 94 contacts → | ||||
Strong evidence “The Ohio Health Information Partnership is a non-profit entity whose mission is to assist physicians and other providers with the adoption and implement of health information…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 24 | 89 contacts → | ||||
Partial evidence “With a mission to use trust to make high-quality healthcare as accessible as a good cup of coffee, IntelliCentrics created the SEC³URE Ethos technology platform.” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
| 25 | 87 contacts → | ||||
Partial evidence “Zus is the only shared health data platform designed to accelerate healthcare data interoperability by providing easy-to-use patient data at the point of care via API, embedded…” Source: RevenueBase Database · checked Sep 20, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: health information exchange companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names health information exchange companies.
- Partial evidence
- Its own public description names part of health information exchange companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name health information exchange companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 349 health information exchange companies based in the United States
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Health information exchange companies based in the United States at a glance
As of Sep 20, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 349 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among health information exchange companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “health information exchange companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names health information exchange companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among health information exchange companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 7,242 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 20, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names health information exchange companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many health information exchange companies are there based in the United States?
RevenueBase identified 349 health information exchange companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Datavant, headquartered in New York City, tops this list with the largest team on record.
Which city has the most health information exchange companies?
New York leads with 10 headquartered companies, followed by Atlanta (9) and Austin (8).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 7,242 verified decision-maker contacts tracked across these 349 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 20, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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