Company lists · Data refreshed September 2026
Top 25 Fermentation biotechnology companies based in the United States
RevenueBase identified 307 fermentation biotechnology companies headquartered in the United States as of September 2026 and tracks 10,728 professional contacts across them, including 4,761 with verified work emails. San Diego is the largest hub.
This list covers fermentation biotechnology companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest fermentation biotechnology companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 1,536 contacts → | ||||
Indirect evidence “POET’s vision is to create a world in sync with nature.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 2 | 1,169 contacts → | ||||
Indirect evidence “Kraton develops, manufactures and markets biobased chemicals and specialty polymers that deliver exceptional value and enhance the lives of people all over the world.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 3 | 781 contacts → | ||||
Indirect evidence “Amyris is a vertically integrated biomanufacturing company that creates specialty molecules for a range of industries, including flavors and fragrances, advanced materials, beauty…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 4 | 471 contacts → | ||||
Indirect evidence “Green Plains Inc.(NASDAQ:GPRE) is a leading biorefining company advancing the transition to a low-carbon world through the production of renewable fuels and sustainable…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 5 | 334 contacts → | ||||
Indirect evidence “Established in 1995 and headquartered in Colwich, Kansas, with a regional office in Brazil, ICM provides innovative technologies, solutions and services to sustain agriculture and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 6 | 270 contacts → | ||||
Indirect evidence “Codexis is redefining what is possible in therapeutic development and manufacturing, leading the technology revolution with efficient, high-quality, and commercially proven…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 7 | 185 contacts → | ||||
Indirect evidence “We’re rethinking everything.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 8 | 173 contacts → | ||||
Indirect evidence “Gusmer Enterprises, Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 9 | 161 contacts → | ||||
Indirect evidence “The EVERY Company combines industry-leading expertise in food technology and flavor to enable the foods of tomorrow, today, for the world’s global food and beverage industries.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 10 | 152 contacts → | ||||
Indirect evidence “We are accelerating the world's transformation to sustainable materials, by replacing fossil fuel sources with plants.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 11 | 150 contacts → | ||||
Indirect evidence “At Solugen, we believe planet-scale change starts with the chemistry we use every day.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 12 | 144 contacts → | ||||
Indirect evidence “Gevo is a next-generation diversified energy company committed to fueling America’s future with cost-effective, drop-in fuels that contribute to energy security, abate carbon, and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 13 | 109 contacts → | ||||
Partial evidence “Phyton Biotech is the world’s leader in pharmaceutical plant cell fermentation (PCF®) technology.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 14 | 105 contacts → | ||||
Indirect evidence “Marquis has a 50-year-long history of driving innovation in American biofuel production, strengthening rural economies, and securing our nation’s energy future.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 15 | 101 contacts → | ||||
Indirect evidence “Scott Laboratories is a growing, family-owned wine-industry distribution company that traces its roots back to 1933.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 16 | 93 contacts → | ||||
Indirect evidence “Elemental Enzymes Ag and Turf, is a life sciences company that discovers, develops and produces innovative products to increase crop yields.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 17 | 91 contacts → | ||||
Partial evidence “Microbial Discovery Group (MDG) is a basic fermentation company with a special emphasis on Research & Development (R&D) with Bacillus; including isolation, characterization, and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 18 | 81 contacts → | ||||
Partial evidence “MycoTechnology captures the magic of fungi with the power of fermentation, developing value-added ingredient solutions for better tasting, healthier and sustainable food.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 19 | 79 contacts → | ||||
Indirect evidence “Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 20 | 66 contacts → | ||||
Strong evidence “Checkerspot is a category defining biotechnology company designing fats and oils through precision fermentation.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 21 | 65 contacts → | ||||
Indirect evidence “White Labs, Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 22 | 63 contacts → | ||||
Partial evidence “Mascoma, as one of Lallemand’s research and development centers, creates new industrial biotechnology products for the global marketplace that enable the efficient and sustainable…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 23 | 62 contacts → | ||||
Partial evidence “Locus Fermentation Solutions (Locus FS) uses patented biomanufacturing technology to deliver biological alternatives to chemicals that accelerate the profitable meeting of…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 24 | 58 contacts → | ||||
Indirect evidence “Lygos is a pioneering sustainable specialty chemicals company, leading the world’s transition toward better, cleaner, and more sustainable products.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 25 | 54 contacts → | ||||
Indirect evidence “DMC is a U.S.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: fermentation biotechnology companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names fermentation biotechnology companies.
- Partial evidence
- Its own public description names part of fermentation biotechnology companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name fermentation biotechnology companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 307 fermentation biotechnology companies based in the United States
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Fermentation biotechnology companies based in the United States at a glance
As of Sep 16, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 307 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among fermentation biotechnology companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “fermentation biotechnology companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names fermentation biotechnology companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among fermentation biotechnology companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 4,761 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names fermentation biotechnology companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many fermentation biotechnology companies are there based in the United States?
RevenueBase identified 307 fermentation biotechnology companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
POET, headquartered in Sioux Falls, tops this list with the largest team on record.
Which city has the most fermentation biotechnology companies?
San Diego leads with 8 headquartered companies, followed by Durham (7) and Chicago (6).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 4,761 verified decision-maker contacts tracked across these 307 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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