Company lists · Data refreshed September 2026
Top 25 Enzyme technology companies based in the United States
RevenueBase identified 131 enzyme technology companies headquartered in the United States as of September 2026 and tracks 3,527 professional contacts across them, including 1,796 with verified work emails. Durham is the largest hub.
This list covers enzyme technology companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 19, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest enzyme technology companies based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 270 contacts → | ||||
Partial evidence “Codexis is redefining what is possible in therapeutic development and manufacturing, leading the technology revolution with efficient, high-quality, and commercially proven…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 2 | 235 contacts → | ||||
Indirect evidence “Huvepharma is a fast growing global pharmaceutical company with a focus on developing, manufacturing and marketing human and animal health products.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 3 | 228 contacts → | ||||
Partial evidence “Watchmaker Genomics is a biotechnology company that specializes in advanced enzymology to develop precision tools for life sciences.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 4 | 150 contacts → | ||||
Indirect evidence “At Solugen, we believe planet-scale change starts with the chemistry we use every day.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 5 | 147 contacts → | ||||
Partial evidence “Extensive chemical synthesis, formulation, manufacturing, and technology expertise.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 6 | 103 contacts → | ||||
Partial evidence “Enzymedica produces cutting edge enzyme formulas that provide targeted support for digestive issues, food intolerances, cardiovascular issues, proper immune function and healthy…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 7 | 95 contacts → | ||||
Strong evidence “Diazyme uses its proprietary enzyme technologies to develop diagnostic reagents which can be used on most automated chemistry analyzers in user-friendly formats.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 8 | 93 contacts → | ||||
Partial evidence “Elemental Enzymes Ag and Turf, is a life sciences company that discovers, develops and produces innovative products to increase crop yields.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 9 | 81 contacts → | ||||
Partial evidence “Fluid Quip Technologies (FQT) is a global technology innovation leader in advanced engineering, process design, construction, and technology integration for the ethanol and…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 10 | 79 contacts → | ||||
Partial evidence “Arzeda, The Protein Design Company™, is a synthetic biology company that creates novel proteins, enzymes and specialty chemical products that compete on performance, cost and…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 11 | 54 contacts → | ||||
Strong evidence “BIO-CAT provides the very latest enzyme technology and custom formulations.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 12 | 53 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 13 | 52 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 14 | 44 contacts → | ||||
Partial evidence “EDT is a bio-industrial, value-added manufacturer of enzyme formulations employing biologically produced enzymes from renewable resources to solve traditional pulp & paper…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 15 | 36 contacts → | ||||
Indirect evidence “Worthington is a privately owned, ISO9001 Certified.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 16 | 35 contacts → | ||||
Indirect evidence “We envision a world where we continuously, sustainably, and affordably improve human life with biocatalysis.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 17 | 35 contacts → | ||||
Partial evidence “Specialty Enzymes & Probiotics is your global resource for quality enzymes and probiotics.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 18 | 29 contacts → | ||||
Indirect evidence “Alphazyme was founded in 2018 by Christopher Benoit, Stephana Petrino and Chad Decker.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 19 | 28 contacts → | ||||
Indirect evidence “Our story begins nearly 3 decades ago with a single product and an industry beginning to expand with the use of ethanol as an oxygenate to reduce carbon monoxide tailpipe…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 20 | 24 contacts → | ||||
Indirect evidence “Arbiom is committed to feeding the world in a sustainable and healthy way.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 21 | 20 contacts → | ||||
Indirect evidence “Zymtronix envisions a future where biomanufacturing is no longer limited by the constraints of cell reproduction.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 22 | 19 contacts → | ||||
Indirect evidence “Based in Columbus, GA, FERMWORX produces the next generation of high-performance biopolymer-based and bio-based fermentation products and offers product development and toll…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 23 | 19 contacts → | ||||
Indirect evidence “This company no longer exists.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 24 | 17 contacts → | ||||
Indirect evidence “Founded in 1985 in Milwaukee, Wisconsin, Molecular Biology Resources, Inc.(MBR) has earned the reputation as a world leader in biochemical manufacturing.” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
| 25 | 16 contacts → | ||||
Partial evidence “Founded in BRI is a global biotechnology company specializing in the research, development and manufacture of high-performance enzyme feed additives that help poultry and swine…” Source: RevenueBase Database · checked Sep 19, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: enzyme technology companies. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names enzyme technology companies.
- Partial evidence
- Its own public description names part of enzyme technology companies, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name enzyme technology companies. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 131 enzyme technology companies based in the United States
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Enzyme technology companies based in the United States at a glance
As of Sep 19, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 131 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among enzyme technology companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “enzyme technology companies”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names enzyme technology companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among enzyme technology companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 1,796 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 19, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names enzyme technology companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many enzyme technology companies are there based in the United States?
RevenueBase identified 131 enzyme technology companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Codexis, INC, headquartered in Redwood City, tops this list with the largest team on record.
Which city has the most enzyme technology companies?
Durham leads with 4 headquartered companies, followed by Boston (3) and Chino (3).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,796 verified decision-maker contacts tracked across these 131 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 19, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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