Company lists · Data refreshed September 2026

Top 18 Enterprise blockchain firms based in San Francisco, United States

RevenueBase identified 51 enterprise blockchain firms headquartered in San Francisco, United States as of September 2026 and tracks 2,486 professional contacts across them, including 455 with verified work emails. Across the United States, New York is the largest hub for this category (64 companies); San Francisco follows with 51.

This list covers enterprise blockchain firms headquartered in San Francisco, United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 28, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 28, 2026 86% judged on-target in blind review
51Companies
2,486Contacts tracked
455Verified emails
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The 18 largest enterprise blockchain firms based in San Francisco, United States

Ranked by team size
Top 18 of 51 enterprise blockchain firms based in San Francisco, United States, ranked by team size, largest first. Data refreshed Sep 28, 2026. RevenueBase Smart Search rates how each company's information relates to enterprise blockchain firms: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 2026501-1,0001,275 contacts →

Strong evidence

“Using proven crypto and blockchain technology honed over a decade, Ripple’s enterprise-grade solutions are faster, more transparent, and more cost-effective than traditional…”

Source: RevenueBase Database · checked Sep 28, 2026
2Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202651-200329 contacts →

Partial evidence

“Alchemy powers the blockchain infrastructure to accelerate the world's leading financial applications.”

Source: RevenueBase Database · checked Sep 28, 2026
3Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-50117 contacts →

Partial evidence

“Traditional blockchains were designed for human users.”

Source: RevenueBase Database · checked Sep 28, 2026
4Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5094 contacts →

Partial evidence

“Blockchain Capital was founded in 2013 with the mission of helping entrepreneurs build world-class companies and projects based on blockchain technology – providing founders with…”

Source: RevenueBase Database · checked Sep 28, 2026
5Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202651-20067 contacts →

Partial evidence

“Quantstamp is a global leader in blockchain security, on a mission to secure the future of web3.”

Source: RevenueBase Database · checked Sep 28, 2026
6Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5053 contacts →

Partial evidence

“Created by Bram Cohen, the inventor of BitTorrent, the underlying open source, public Chia blockchain provides the secure and regulatory-compliant infrastructure for One Market.”

Source: RevenueBase Database · checked Sep 28, 2026
7Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5040 contacts →

Indirect evidence

“Onboard users with wallets, build & deploy smart contracts, accept fiat with payments, and scale apps with infrastructure, on any EVM chain.”

Source: RevenueBase Database · checked Sep 28, 2026
8Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5035 contacts →

Strong evidence

“Loyyal is at the forefront of loyalty and payments innovation, offering a cutting-edge Enterprise SaaS Suite powered by patented blockchain technology.”

Source: RevenueBase Database · checked Sep 28, 2026
9Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5034 contacts →

Strong evidence

“Constellation is the world’s only Blockchain technology designed for Big Data, providing infrastructure for an open decentralized data marketplace and an enterprise-grade software…”

Source: RevenueBase Database · checked Sep 28, 2026
10Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5032 contacts →

Partial evidence

“Powerful Chain Infrastructure Work with our renowned team of experts for your custom chain, backed by our powerful enterprise-grade infrastructure.”

Source: RevenueBase Database · checked Sep 28, 2026
11Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5023 contacts →

Indirect evidence

“Eclipse is a verifiable computing company based in San Francisco, founded in 2022.”

Source: RevenueBase Database · checked Sep 28, 2026
12Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-5018 contacts →

Partial evidence

“Ambisafe is a globally recognized blockchain-based software provider.”

Source: RevenueBase Database · checked Sep 28, 2026
13Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 20261-109 contacts →

Partial evidence

“Build your WEB3 Document Issuing System on DOCCHAIN.IO, for Enterprises.”

Source: RevenueBase Database · checked Sep 28, 2026
14Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-504 contacts →

Indirect evidence

“Bridging the gap between Web2 & Web3”

Source: RevenueBase Database · checked Sep 28, 2026
15Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 2026201-5003 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 28, 2026
16Indirect evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 202611-503 contacts →

Indirect evidence

“We are a startup that cofound startups.”

Source: RevenueBase Database · checked Sep 28, 2026
17Strong evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 20261-102 contacts →

Strong evidence

“A cybersecurity company, developing a more secure, faster and scalable blockchain solution for enterprises.”

Source: RevenueBase Database · checked Sep 28, 2026
18Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 28, 20261-101 contacts →

Partial evidence

“Agrow Labs provides sustainable blockchain solutions, empowering businesses to redefine possibilities of blockchain technology.”

Source: RevenueBase Database · checked Sep 28, 2026

Showing 18 of 51 enterprise blockchain firms based in San Francisco, United States

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Enterprise blockchain firms based in San Francisco, United States at a glance

As of Sep 28, 2026
18.3%Verified-email coverage
48.7Average contacts per company
11-50Median size (employees)
Sep 28, 2026Page data refreshed

Companies by employee count

1-10
21
11-50
21
51-200
5
201-500
3
501-1,000
1

Email recency for this list is measured across the whole United States list rather than for San Francisco, so it is reported there. Company counts and contact totals on this page are exact for San Francisco, over 51 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among enterprise blockchain firms, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in San Francisco, United States whose own description of what they do matches “enterprise blockchain firms”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names enterprise blockchain firms), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among enterprise blockchain firms, and records with no verified work email. Companies headquartered outside San Francisco are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 455 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 28, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names enterprise blockchain firms, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many enterprise blockchain firms are there based in San Francisco, United States?

RevenueBase identified 51 enterprise blockchain firms headquartered in San Francisco, United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Ripple, headquartered in San Francisco, tops this list with the largest team on record.

Which city in the United States has the most enterprise blockchain firms?

New York leads the United States with 64 headquartered companies, followed by San Francisco (51) and Miami (36).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 455 verified decision-maker contacts tracked across these 51 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 28, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.