Company lists · Data refreshed September 2026

Top 25 Electronic trial master file software companies based in the United States

RevenueBase identified 51 electronic trial master file software companies headquartered in the United States as of September 2026 and tracks 1,302 professional contacts across them, including 259 with verified work emails. Austin is the largest hub.

This list covers electronic trial master file software companies headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 14, 2026.

Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.

How to read this list HQ checked on every row RevenueBase Smart Search rating on every row Refreshed Sep 14, 2026 86% judged on-target in blind review
51Companies
1,302Contacts tracked
259Verified emails
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The 25 largest electronic trial master file software companies based in the United States

Ranked by team size
Top 25 of 51 electronic trial master file software companies based in the United States, ranked by team size, largest first. Data refreshed Sep 14, 2026. RevenueBase Smart Search rates how each company's information relates to electronic trial master file software companies: strong evidence (its own description names it), partial (names part of it), indirect (matched on the rest of its profile rather than the description shown). Click a contact count to view that company's people.
#CompanyRevenueBase Smart SearchHeadquartersEmployeesContacts
1Indirect evidenceCleveland, OH, United StatesHQ checked Sep 14, 2026n/a455 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 14, 2026
2Partial evidenceSan Francisco, CA, United StatesHQ checked Sep 14, 202651-200177 contacts →

Partial evidence

“At Medrio, we're fueled by an ambitious vision: to improve 100 million lives by enabling secure, reliable, and efficient clinical trials.”

Source: RevenueBase Database · checked Sep 14, 2026
3Indirect evidenceMalvern, PA, United StatesHQ checked Sep 14, 2026201-500145 contacts →

Indirect evidence

Source: RevenueBase Database · checked Sep 14, 2026
4Indirect evidencePrinceton, NJ, United StatesHQ checked Sep 14, 20261,001-5,00073 contacts →

Indirect evidence

“Visit Bioclinica!”

Source: RevenueBase Database · checked Sep 14, 2026
5Indirect evidenceAustin, TX, United StatesHQ checked Sep 14, 202611-5050 contacts →

Indirect evidence

“Prelude is the only R&D platform built exclusively for animal health and nutrition.”

Source: RevenueBase Database · checked Sep 14, 2026
6Indirect evidenceFt. Lauderdale, FL, United StatesHQ checked Sep 14, 202651-20032 contacts →

Indirect evidence

“OmniComm Systems provides a critical role in enhancing patient lives by shortening time to market of essential life-saving treatments.”

Source: RevenueBase Database · checked Sep 14, 2026
7Strong evidencePrinceton, NJ, United StatesHQ checked Sep 14, 202611-5028 contacts →

Strong evidence

“WHO WE ARE Data Management 365 is an innovative software development company with profound experience in clinical trials.”

Source: RevenueBase Database · checked Sep 14, 2026
8Indirect evidenceAustin, TX, United StatesHQ checked Sep 14, 202611-5022 contacts →

Indirect evidence

“Modern eClinical tools that work the way you do.”

Source: RevenueBase Database · checked Sep 14, 2026
9Indirect evidencePhoenix, AZ, United StatesHQ checked Sep 14, 202611-5019 contacts →

Indirect evidence

“About Us Welcome to Anzu®, where cutting-edge technology meets innovative clinical data management.”

Source: RevenueBase Database · checked Sep 14, 2026
10Partial evidenceBoston, MA, United StatesHQ checked Sep 14, 202611-5016 contacts →

Partial evidence

“Yonalink provides EHR-to-EDC streaming and AI-driven CRF mapping along with other clinical trial data management solutions.”

Source: RevenueBase Database · checked Sep 14, 2026
11Indirect evidenceNashville, TN, United StatesHQ checked Sep 14, 202611-5013 contacts →

Indirect evidence

“Cloud Concinnity® is an integrated platform that centralizes, simplifies and automates control of data, communications, process management & reporting, while unlocking the value…”

Source: RevenueBase Database · checked Sep 14, 2026
12Partial evidenceCharlotte, NC, United StatesHQ checked Sep 14, 202611-5011 contacts →

Partial evidence

“We provide Clinical Data Management & EDC & SAS Programming services for clinical trials.”

Source: RevenueBase Database · checked Sep 14, 2026
13Indirect evidenceAustin, TX, United StatesHQ checked Sep 14, 202611-5010 contacts →

Indirect evidence

“Datatrak powered by Fountayn provides technology and data solutions for healthcare organizations.”

Source: RevenueBase Database · checked Sep 14, 2026
14Indirect evidenceYpsilanti, MI, United StatesHQ checked Sep 14, 20261-1010 contacts →

Indirect evidence

“DDOTS, Inc.”

Source: RevenueBase Database · checked Sep 14, 2026
15Strong evidenceOakland, CA, United StatesHQ checked Sep 14, 202611-509 contacts →

Strong evidence

Trial By Fire Solutions is an eClinical software company focusing on clinical trial management systems (CTMS).”

Source: RevenueBase Database · checked Sep 14, 2026
16Strong evidenceHopkins, MN, United StatesHQ checked Sep 14, 202611-508 contacts →

Strong evidence

“Clindex® Clinical Trial Software A Clinical Data Management System (CDMS), Clinical Trial Management System (CTMS) and Electronic Data Capture System (EDC) all in one powerful…”

Source: RevenueBase Database · checked Sep 14, 2026
17Partial evidenceWilmington, United StatesHQ checked Sep 14, 202611-507 contacts →

Partial evidence

“Intrinsic Clinical Systems is the result of decades of pharmaceutical, clinical trial, project management, and operations experience.”

Source: RevenueBase Database · checked Sep 14, 2026
18Partial evidenceUniversity Park, FL, United StatesHQ checked Sep 14, 20261-106 contacts →

Partial evidence

“A modern clinical trial management system focused on execution: clear workflows, accountable tasking, and compliance-minded documentation built for sites, sponsors, and CROs.”

Source: RevenueBase Database · checked Sep 14, 2026
19Strong evidenceWilmington, DE, United StatesHQ checked Sep 14, 202611-505 contacts →

Strong evidence

“Trialogics is a clinical trial software and service provider dedicated to meeting today’s clinical trial needs.”

Source: RevenueBase Database · checked Sep 14, 2026
20Partial evidenceCleveland, OH, United StatesHQ checked Sep 14, 202651-2004 contacts →

Partial evidence

“From the pioneers of eDocs and Complion eISF, our user-friendly electronic document management and regulatory systems are built for clinical research sites and academic medical…”

Source: RevenueBase Database · checked Sep 14, 2026
21Indirect evidencePortsmouth, NH, United StatesHQ checked Sep 14, 20261-103 contacts →

Indirect evidence

“Historically a boutique provider of hosted clinical data management systems to a limited number of “referral only” clients, Simplified Clinical has become a leader in EDC/CDMS…”

Source: RevenueBase Database · checked Sep 14, 2026
22Partial evidenceWilmington, DE, United StatesHQ checked Sep 14, 202611-503 contacts →

Partial evidence

“Right now, your Vault is filled with everything that drives your trials-documents, data, workflows, and the decisions that move them forward.”

Source: RevenueBase Database · checked Sep 14, 2026
23Partial evidenceCincinnati, OH, United StatesHQ checked Sep 14, 20261-102 contacts →

Partial evidence

“At Docutrial, we are revolutionizing the way you capture and process clinical trial data.”

Source: RevenueBase Database · checked Sep 14, 2026
24Partial evidenceSan Bernardino, CA, United StatesHQ checked Sep 14, 20261-102 contacts →

Partial evidence

“We create solutions to bridge the gap between discovery and trial.”

Source: RevenueBase Database · checked Sep 14, 2026
25Partial evidenceTampa, FL, United StatesHQ checked Sep 14, 20261-101 contacts →

Partial evidence

“Mediant Health® is the parent company of Haversac™, a next generation toolbox of clinical study software and service solutions providing new and improved user interface…”

Source: RevenueBase Database · checked Sep 14, 2026

Showing 25 of 51 electronic trial master file software companies based in the United States

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Electronic trial master file software companies based in the United States at a glance

As of Sep 14, 2026
19.9%Verified-email coverage
25.5Average contacts per company
11-50Median size (employees)
7.8%Largest-city concentration · Austin
Sep 14, 2026Page data refreshed

Companies by employee count

1-10
17
11-50
26
51-200
6
201-500
1
1,001-5,000
1

Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 51 companies.

How this list was built

Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among electronic trial master file software companies, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.

Source
The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
What qualifies
Companies headquartered in the United States whose own description of what they do matches “electronic trial master file software companies”. Matching reads each company's description, not its industry code or its name.
RevenueBase Smart Search
RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names electronic trial master file software companies), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
What we exclude
Companies whose own description does not clearly place them among electronic trial master file software companies, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
Match quality
In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
Ranking
Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
Verification
Every listed company carries at least one verified work email, 259 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
Refresh
This page's figures were pulled from the company graph on September 14, 2026. Lists refresh periodically as the graph is re-checked.
Corrections
Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.

Frequently asked

What is RevenueBase Smart Search?

RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names electronic trial master file software companies, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.

How many electronic trial master file software companies are there based in the United States?

RevenueBase identified 51 electronic trial master file software companies headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.

What is the largest company on this list?

Datatrak, headquartered in Cleveland, tops this list with the largest team on record.

Which city has the most electronic trial master file software companies?

Austin leads with 4 headquartered companies, followed by Wilmington (4) and Charlotte (3).

How do I get contact information for these companies?

A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 259 verified decision-maker contacts tracked across these 51 companies.

How current is this list?

The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 14, 2026.

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About this data

RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.