Company lists · Data refreshed September 2026
Top 25 Drug substance manufacturers based in the United States
RevenueBase identified 141 drug substance manufacturers headquartered in the United States as of September 2026 and tracks 6,059 professional contacts across them, including 1,684 with verified work emails. Charlotte is the largest hub.
This list covers drug substance manufacturers headquartered in the United States, matched on what each company actually does as described in its own words. Ranked by team size, largest first. Every row shows the company's own description, its RevenueBase Smart Search rating, and when it was last checked. Data refreshed September 16, 2026.
Published by RevenueBase, a B2B data infrastructure company. This list was built with RevenueBase Smart Search, the natural-language company search RevenueBase customers use to build their own targeted lists and unlock verified emails and direct dials at the companies on them. How these lists are built and judged.
The 25 largest drug substance manufacturers based in the United States
Ranked by team size| # | Company | Contacts | |||
|---|---|---|---|---|---|
| 1 | 574 contacts → | ||||
Indirect evidence “Veranova is a global leader in process development and manufacturing of active pharmaceutical ingredients (APIs), with a focus on specialty and complex chemistry for small…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 2 | 540 contacts → | ||||
Indirect evidence “Established in 2019 by SK Inc, SK pharmteco is a global contract development and manufacturing organization (CDMO) with operations across the U.S, Europe, and South Korea.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 3 | 304 contacts → | ||||
Partial evidence “For over 75 years, we have supplied the pharmaceutical industry with highly engineered products and innovative solutions that improve the formulation and delivery of drug products…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 4 | 259 contacts → | ||||
Indirect evidence “Jost Chemical Co.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 5 | 237 contacts → | ||||
Indirect evidence “Who we are: On June 9, 2017, Olon S.p.A, a leading Active Pharmaceutical Ingredients (API) contract development and manufacturing organization (CDMO) and Generics supplier…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 6 | 232 contacts → | ||||
Indirect evidence “Spectrum Chemical Mfg.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 7 | 184 contacts → | ||||
Indirect evidence “Jubilant Pharma Limited is a global integrated pharmaceutical company offering a wide range of products and services to our customers across geographies.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 8 | 177 contacts → | ||||
Indirect evidence “QCL is science driven, quality focused, and responsive.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 9 | 174 contacts → | ||||
Indirect evidence “Norwich is a leading provider of contract manufacturing and clinical services for the pharmaceuticals industry.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 10 | 152 contacts → | ||||
Partial evidence “BioSpectra Inc.(BSI), is a privately-owned manufacturer of premium pharmaceutical ingredients and bulk, cGMP fine chemicals, in service to many leading BioPharma companies around…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 11 | 148 contacts → | ||||
Partial evidence “Noramco, headquartered in Wilmington, Delaware, is a global leader in the production of controlled substances for the pharmaceutical industry, for medicines used to treat…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 12 | 141 contacts → | ||||
Indirect evidence “Apicore LLC, a wholly owned subsidiary of RK Pharma Inc is a leading process R&D and API manufacturing service provider for the worldwide pharmaceutical industry.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 13 | 116 contacts → | ||||
Indirect evidence “Ascent Pharmaceuticals, Inc, headquartered in Central Islip, New York, is a leading generic pharmaceutical company specializing in the development, manufacturing, and analysis of…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 14 | 81 contacts → | ||||
Indirect evidence “LEADING THE SUPPLY OF HIGH QUALITY GENERIC APIs 21st Century economic, social, technical and regulatory dynamics are dramatically changing the pharmaceutical world making it more…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 15 | 74 contacts → | ||||
Indirect evidence “Offering Seamless CMC Development Services Including Process Research & Development and Delivery of cGMP APIs” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 16 | 71 contacts → | ||||
Indirect evidence “Antheia is the advanced biosynthesis company transforming pharmaceutical manufacturing and innovation for the 21st century.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 17 | 56 contacts → | ||||
Partial evidence “Lacamas Laboratories manufactures and delivers high quality products at the best price possible, on time every time.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 18 | 53 contacts → | ||||
Indirect evidence “Pharm Ops Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 19 | 44 contacts → | ||||
Indirect evidence “Our mission is to deliver quality products at affordable prices – bringing value to our customer base while providing savings and choice to patients nationwide.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 20 | 44 contacts → | ||||
Indirect evidence “Wilmington PharmaTech (WPT) is a U.S-based Contract Research, Development, and Manufacturing Organization (CRDMO) providing end-to-end solutions for the pharmaceutical and…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 21 | 41 contacts → | ||||
Partial evidence “Agno Pharmaceuticals is a global CDMO supplying critical RSMs, intermediates, active pharmaceutical ingredients (APIs), highly potent APIs, sterile APIs, and sterile drug product…” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 22 | 40 contacts → | ||||
Indirect evidence “Incorporated in 2019, Sancilio & Company is wholly owned by Dr.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 23 | 35 contacts → | ||||
Partial evidence “Rapid drug development and patented advanced pharmaceutical manufacturing company providing essential medicines through scalable domestic API production.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 24 | 32 contacts → | ||||
Indirect evidence Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
| 25 | 31 contacts → | ||||
Indirect evidence “Pharmatek Laboratories, Inc.” Source: RevenueBase Database · checked Sep 16, 2026Thanks. The Data Team will review it. | |||||
RevenueBase Smart Search
RevenueBase Smart Search assesses information from a company’s LinkedIn profile, information supplied directly by the company, its website, and other publicly available sources. It uses that information to rate how closely the company relates to this list’s category: drug substance manufacturers. Every row carries its rating and the description the rating was read from, so each one can be checked rather than taken on trust.
- Strong evidence
- The company's own public description of its business names drug substance manufacturers.
- Partial evidence
- Its own public description names part of drug substance manufacturers, so it works in or next to the category without describing itself that way.
- Indirect evidence
- The description shown does not name drug substance manufacturers. The match rests on the rest of the company's public profile rather than the one sentence quoted here, so this is the rating to check first.
RevenueBase Smart Search is how these lists are built: RevenueBase's data engine and AI assemble the companies that match a category defined in a user's own words, so a list can be about what companies actually do rather than about whichever industry code they were filed under.
Showing 25 of 141 drug substance manufacturers based in the United States
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Drug substance manufacturers based in the United States at a glance
As of Sep 16, 2026Companies by employee count
Email recency for this list is measured worldwide rather than for United States, so it is reported there. Company counts and contact totals on this page are exact for United States, over 141 companies.
How this list was built
Company categories are rarely black and white. RevenueBase reads each company's own description of its business to decide whether it belongs among drug substance manufacturers, so some rows will be adjacent to the category rather than pure plays. The description and RevenueBase Smart Search rating on every row are there so you can check each match yourself.
- Source
- The RevenueBase company graph: 60 million companies and 398.9 million professional contacts resolved from primary sources, queried with RevenueBase Smart Search, the natural-language company search available to every RevenueBase user.
- What qualifies
- Companies headquartered in the United States whose own description of what they do matches “drug substance manufacturers”. Matching reads each company's description, not its industry code or its name.
- RevenueBase Smart Search
- RevenueBase Smart Search is how this list is assembled and how each row is rated. RevenueBase's data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to a category defined in a user's own words. Each row is rated strong evidence (its own description names drug substance manufacturers), partial evidence (it names part of the category) or indirect evidence (the description shown names none of it and the match rests on the rest of the company's profile). The description supporting each rating is quoted on the row.
- What we exclude
- Companies whose own description does not clearly place them among drug substance manufacturers, and records with no verified work email. Companies headquartered outside United States are excluded even when they keep an office there.
- Match quality
- In blind human judging of this matching method, 86% of matched companies were on target. Expect roughly 1 in 7 rows to be adjacent to the category rather than a pure play. Every row shows the company's own description and its RevenueBase Smart Search rating so you can judge each match yourself. Read the full methodology: how the lists are built, how the judging worked, and what the figure means.
- Ranking
- Team size, largest first: companies are ordered by the number of professionals RevenueBase tracks at each one. Employee ranges shown are reported bands, for context.
- Verification
- Every listed company carries at least one verified work email, 1,684 across the full list. Contacts re-verify on a rolling cadence, and each contact's own verification date is shown inside RevenueBase.
- Refresh
- This page's figures were pulled from the company graph on September 16, 2026. Lists refresh periodically as the graph is re-checked.
- Corrections
- Wrong category, wrong headquarters, or a company that has closed? Use “Report an issue” on any row. Reports go to the RevenueBase Data Team and feed back into the company graph.
Frequently asked
What is RevenueBase Smart Search?
RevenueBase Smart Search is how RevenueBase decides which companies belong on this list and how strongly each one fits. Its data engine and AI assess a company's LinkedIn profile, information supplied directly by the company, its website and other publicly available information, then relate it to the category the list is about. Each row is rated strong evidence when the company's own description names drug substance manufacturers, partial evidence when it names part of the category, and indirect evidence when the description shown names none of it and the match rests on the rest of the company's profile.
How many drug substance manufacturers are there based in the United States?
RevenueBase identified 141 drug substance manufacturers headquartered in the United States as of September 2026, matched on each company's own description of what it does rather than its industry code.
What is the largest company on this list?
Veranova, headquartered in Devens, tops this list with the largest team on record.
Which city has the most drug substance manufacturers?
Charlotte leads with 5 headquartered companies, followed by Wilmington (4) and Fairfield (3).
How do I get contact information for these companies?
A free RevenueBase account lets you run this exact search and work the top results, verified emails and direct dials included. Upgrading unlocks all 1,684 verified decision-maker contacts tracked across these 141 companies.
How current is this list?
The list refreshes periodically as the company graph is re-checked. This page's figures were pulled on September 16, 2026.
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About this data
RevenueBase is a B2B data infrastructure company. Its company graph covers 60 million companies and 398.9 million professional contacts, with emails verified on a rolling cadence rather than scraped once and left to decay. These company lists are generated directly from that graph with RevenueBase Smart Search, the same natural-language company search every RevenueBase user has: describe a market in plain words, get the companies that match, and add verified emails and direct dials for the people at them. It is the same data that powers RevenueBase's B2B data products, and a free account includes 500 credits to start. How these lists are built and judged.
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